Recombinant Murine FGF-Basic
产品编号:
AF-450-33
别名:
Fibroblast Growth, Factor-basic, FGF-2, HBGF-2, Prostatropin
描述:
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant murine FGF-basic is a 16.2 kDa protein consisting of 145 amino acid residues. Manufactured using all non-animal reagents.
氨基酸序列:
MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
原产国:
USA
仅用于研究。不适用于诊断或治疗。
