本公司提供科研hnRNP M/CEAR异质性核糖核蛋白M抗体，抗体质量可靠，订购hnRNP M/CEAR异质性核糖核蛋白M抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：异质性核糖核蛋白M抗体
英文名称：Anti-hnRNP M/CEAR
货号：bs-8505R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 77kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, hrs, chk
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm, such as hnRNP E1 and E2. hnRNP E1 may function in the cytoplasm as a translational regulatory protein, while hnRNP E2 stabilizes mRNA to enhance polioviral mRNA translation. hnRNP M is involved in pre-mRNA splicing and in stress-induced transient splicing arrest.Subunit : Identified in the spliceosome C complex.Subcellular Location : Nucleus, nucleolus.Similarity : Contains 3 RRM (RNA recognition motif) domains.