【Molecular Wt.】42 kDa

【Description】Selectins, also designated SELL antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Lex as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

【Species Reactivity】Human

【Tested applications】WB;ICC

【Antibody type】Mouse monoclonal Antibody

【Immunogen】Recombinant protein

【Positive control】Human CD62L recombinant protein, CD62L -hIgGFc transfected HEK293 cell lysate, Hela, MCF-7.

【Conjugate】Non-conjugated

【Alternative names】A.11 antibody
AI528707 antibody
CD62 antigen ligand antibody
CD62 antigen-like family member L antibody
CD62L antibody
gp90-MEL antibody
IgA nephropathy, susceptibility to, included antibody
L Selectin antibody
L-selectin antibody
LAM-1 antibody
LAM1 antibody
LECAM1 antibody
LEU8 antibody
Leukocyte adhesion molecule 1 antibody
Leukocyte surface antigen Leu-8 antibody
Leukocyte-endothelial cell adhesion molecule 1 antibody
Lnhr antibody
LSEL antibody
Ly-22 antibody
Ly-m22 antibody
Lyam-1 antibody
LYAM1 antibody
LYAM1_HUMAN antibody
Lymph node homing receptor antibody
Lymphocyte adhesion molecule 1 antibody
Lymphocyte antigen 22 antibody
Lymphocyte surface MEL-14 antigen antibody
MEL-14 antibody
Pln homing receptor antibody
PLNHR antibody
Selectin L antibody
Selectin, lymphocyte antibody
SELL antibody
TQ1 antibody

【Form】Liquid

【Stroage】Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

【Stroage Buffer】1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

【Isotype】IgG1

【Purity】Protein A purified.

【Subcellular location】Membrane.

【Background References】1. Gallatin WM et al. A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. J Immunol 177:5-9 (2006).
2. Chen BJ et al. Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease. Blood 103:1534-41 (2004).

【DatasheetURL】http://www.huabio.com/upload/EM1707-76.pdf

【Uniprot ID】P14151(Human)

【Raised in】Mouse

【Clone No.】