FITC标记的HRAS样抑制因子3抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-09-12 22:15

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-2145R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-Hrasls3/FITC
抗体名Anti-Hrasls3/FITC
标记物FITC标记
宿主Human, Mouse, Rat,
适应物种Human, Mouse, Rat,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的HRAS样抑制因子3抗体
英文名称Anti-Hrasls3/FITC
中文名称FITC标记的HRAS样抑制因子3抗体
别 名H rev 107 protein homolog; HRAS like suppressor 3; HREV107 3; HREV107; Renal carcinoma antigen NY REN 65; Adipose specific phospholipase A2; Group XVI phospholipase A2; HREV107; HRSL3_MOUSE; AdPLA; HRSL3; HRASLS3; HREV107-1; HREV107-3; H-REV107-1.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量18kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from the middle of mouse Hrasls3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
HRASLS3 specifically catalyzes the release of fatty acids from phospholipids in adipose tissue and also has a weak lysophospholipase activity. It is a tumor suppressor that may be involved in interferon-dependent cell death.

Function:
Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. N-and O-acylation activity is hardly detectable. Also has weak lysophospholipase activity.

Subunit:
Interacts with PPP2R1A; this interaction might decrease PP2A activity.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential). Cytoplasm. Cytoplasm, perinuclear region.

Tissue Specificity:
Ubiquitously expressed in normal tissues but down-regulated in primary carcinomas or in many cell lines derived from tumors. Highly expressed in white adipose tissue and in adipocytes. Expressed at lower levels in brown adipose tissue.

Similarity:
Belongs to the H-rev107 family.

Database links:

Entrez Gene: 11145 Human

Entrez Gene: 225845 Mouse

Omim: 613867 Human

SwissProt: P53816 Human

SwissProt: Q8R3U1 Mouse

Unigene: 502775 Human

Unigene: 274810 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.