RECK antibody

Product Name RECK antibody

Catalog No PAab10074

Packing 100ul

Form liquid

Alternative Name RECK, ST15, reversion-inducing cysteine-rich protein with Kazal motifs

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Negatively regulates matrix metalloproteinase-9(MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

Immunogen reversion-inducing-cysteine-rich protein with kazal motifs

Specificity Human

Tested Application ELISA, IHC

Recommended dilution IHC: 1:20-1:200

IHC use Immunohistochemistry of paraffin-embedded human kidney using PAab10074( RECK Antibody) at dilution of 1:100

WB use

Protein Information

Gene ID 8434

Uniprot ID O95980

Calculated MW 110 kDa

Research Area cancer