FAM134B antibody antibody

¥1380 - 2200
康朗生物
中国/美国/德国
2021-09-13 04:41

上海康朗生物科技有限公司

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上海康朗生物科技有限公司
蔡盼
18217752821 021-61998208
shklbio@163.com
产品属性
供应商上海康朗生物科技有限公司
数量大量
目录编号kl-13136R
克隆性多克隆
抗原来源Rabbit
保质期12个月
抗体英文名FAM134B antibody antibody
抗体名FAM134B蛋白抗体
宿主Rabbit
适应物种Human, Mouse, Rat, Cow, Rabbit,
免疫原KLH conjugated synthetic peptide derived from human FAM134B:210-310/497
亚型IgG
形态冻干粉或液体
应用范围ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
浓度1mg/ml
保存条件-20 °C
规格100ul 200ul
产品说明
FAM134B antibody
中文名称FAM134B蛋白抗体
别 名F134B_HUMAN; FAM134B; family with sequence similarity 134 member B; HSAN2B; JK 1; JK1; Protein FAM134B.
规格价格100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书100ul 200ul
研究领域细胞生物 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Rabbit,
产品应用ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量55kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FAM134B:210-310/497
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:
Required for long-term survival of nociceptive and autonomic ganglion neurons.

Function:
Required for long-term survival of nociceptive and autonomic ganglion neurons. 

Subcellular Location:
Golgi apparatus; cis-Golgi network membrane.

DISEASE:
Defects in FAM134B are the cause of hereditary sensory and autonomic neuropathy type 2B (HSAN2B) [MIM:613115]. A form of hereditary sensory and autonomic neuropathy, a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN2B is an autosomal recessive disorder characterized by impairment of pain, temperature and touch sensation. Onset occurs in the first or second decade, with impaired nociception and progressive mutilating ulceration of the hands and feet with osteomyelitis and acroosteolysis. Amputations of the hands and feet are common. Autonomic dysfunction includes hyperhidrosis, urinary incontinence, and slow pupillary light response.

Similarity:
Belongs to the FAM134 family.

SWISS:
Q9H6L5

Gene ID:
54463

Database links:

Entrez Gene: 54463 Human

Entrez Gene: 66270 Mouse

Entrez Gene: 619558 Rat

Omim: 613114 Human

SwissProt: Q9H6L5 Human

SwissProt: Q8VE91 Mouse

SwissProt: Q5FVM3 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品图片
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM134B) Polyclonal Antibody, Unconjugated (bs-13136R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM134B) Polyclonal Antibody, Unconjugated (bs-13136R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

Paraformaldehyde-fixed, paraffin embedded (Mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM134B) Polyclonal Antibody, Unconjugated (bs-13136R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; 
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
Incubation: Anti-FAM134B Polyclonal Antibody, Unconjugated(bs-13136R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining