本公司提供科研HSPB2热休克蛋白B2抗体，抗体质量可靠，订购HSPB2热休克蛋白B2抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：热休克蛋白B2抗体
英文名称：Anti-HSPB2
货号：bs-4782R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 20kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, dog, Rb, cow, hrs
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis.Subunit : Interacts with DMPK; may enhance its kinase activity.Subcellular Location : Cytoplasm. Nucleus. Localizes to nuclear foci.Tissue Specificity : Expressed preferentially in skeletal muscle and heart.Similarity : Belongs to the small heat shock protein (HSP20) family.