关键词：ERα;雌激素受体α ;雌激素受体α ;ESR1; ESR; NR3A1; Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1

中文名称：雌激素受体α (phospho S雌激素受体305)多克隆抗体/ERα (phospho Ser305) Polyclonal Antibody

英文名称：ERα (phospho Ser305) Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP54175.pdf

产品描述：兔抗-雌激素受体α (phospho S雌激素受体305) 多克隆抗体

ESR1 encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The estrogen receptor 1 localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

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