FITC标记的谷氨酸脱羧酶65+谷氨酸脱羧酶67抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-09-18 13:58

上海联迈生物工程有限公司

我要认领
上海联迈生物工程有限公司
周经理
13052188602 021-67680335
shlmai@163.com
产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-13263R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-GAD65 + GAD67/FITC
抗体名Anti-GAD65 + GAD67/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
适应物种Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围ICC=1:50-200 IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的谷氨酸脱羧酶65+谷氨酸脱羧酶67抗体
英文名称Anti-GAD65 + GAD67/FITC
中文名称FITC标记的谷氨酸脱羧酶65+谷氨酸脱羧酶67抗体
别 名65 kDa glutamic acid decarboxylase; DCE 2; DCE2; GAD 2; GAD 65; GAD-2; GAD-65;GAD 65, GAD2; Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa); Glutamate Decarboxylase 2; Glutamate Decarboxylase 65; Glutamate decarboxylase 65 kDa isoform; Glutamic Acid Decarboxylase 2; Glutamic Acid Decarboxylase 65; DCE1_HUMAN; DCE2_HUMAN.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域细胞生物 神经生物学 细胞类型标志物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量65+67kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GAD65 + GAD67
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.

Function:
Catalyzes the production of GABA. 

Subcellular Location:
Cytoplasm; cytosol. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.

Similarity:
Belongs to the group II decarboxylase family. 

Database links:

Entrez Gene: 2572 Human

Entrez Gene: 14417 Mouse

Entrez Gene: 24380 Rat

Omim: 138275 Human

SwissProt: Q05329 Human

SwissProt: Q5VZ29 Human

SwissProt: Q5VZ30 Human

SwissProt: P48320 Mouse

SwissProt: Q548L4 Mouse

SwissProt: Q05683 Rat

Unigene: 231829 Human

Unigene: 4784 Mouse

Unigene: 29951 Rat

Entrez Gene: 2571 Human

Entrez Gene: 14415 Mouse

Entrez Gene: 24379 Rat

Omim: 605363 Human

SwissProt: Q99259 Human

SwissProt: P48318 Mouse

SwissProt: P18088 Rat

Unigene: 420036 Human

Unigene: 272120 Mouse

Unigene: 91245 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.