产品英文名称：
Myelin Oligodendrocyte Glycoprotein

英文简称:
MOG

中文名称:
髓鞘少突胶质细胞糖蛋白

背景资料:
MOG is a transmembrane protein expressed on the surface of oligodendrocyte cell and on the outermost surface of myelin sheaths. MOG comprises about 0.1% of total CNS myelin protein. The MOG gene is a member of the immunoglobulin gene superfamily and is found within the MHC. The MOG gene is found on chromosome 6p21.3-p22. Myelin Oligodendrocyte Glycoprotein is a glycoprotein thought to be significant in the process of myelinization of nerves in the central nervous system （CNS）. MOG peptide （35-55） is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing- remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical， histophathologic， and immunologic similarities with multiple sclerosis （MS）， the MOG induced demyelinating encephalomyelitis may serve as a model for investigating MS.

产品描述:
Myelin Oligodendrocyte Glycoprotein is a single， non-glycosylated polypeptide chain containing 21 amino acids and having a molecular mass of 2582 Dalton， the molecular formula: C118H177N35O29S.
来源宿主:


序列:
H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH.

溶解建议:
Sterile Filtered White lyophilized （freeze-dried） powder. The protein was lyophilized with no additives. It is recommended to reconstitute the lyophilized MOG in sterile 18MΩ-cm H2O not less than 100ug/ml， which can then be further diluted to other aqueous solutions.

保存建议：
Lyophilized MOG although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution MOG should be stored at 4℃ between 2-7 days and for future use below-18℃.For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.Please prevent freeze-thaw cycles.
其他简介：

ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
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