ANKRD17 Antibody
Cat#：PL0306072
Isotype:Rabbit Polyclonal IgG
Immunogen：Peptide derived from human ANKRD17.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
ANKRD17 is a 2,603 amino acid protein that contains 25 ankyrin repeats and one KH domain. ANKRD17 is expressed in bone marrow and is thought to be involved in liver development. ANKRD17 localizes to the cytoplasm and the nucleus. ANKRD17 exists as five alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 4. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Alternate Names：
ANKRD 17; ANKRD-17; Ankyrin repeat domain protein 17; Ankyrin repeat domain-containing protein 17; ANR17_HUMAN; FLJ22206; Gene trap ankyrin repeat; Gene trap ankyrin repeat protein; GTAR; KIAA0697; NY BR 16; Serologically defined breast cancer antigen NY-BR-16.
Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Pig, Cow, , Sheep
Application Notes:E: 1:500-1000 IHC: 1:100-500 IF: 1:50-200
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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