NCBI Gene Id: 83785
Swissprot Id: P16612-2
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant rat VEGF is a 38.5 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OPBG00477

Protein SDS-PAGE

Vegfa Recombinant Protein (Rat) (OPBG00477) using SDS-PAGE