FITC标记的细胞周期依赖性激酶抑制相关蛋白抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-11-12 17:44

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-6391R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-P15RS/FITC
抗体名Anti-P15RS/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Pig, Cow, Horse,
适应物种Human, Mouse, Rat, Pig, Cow, Horse,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的细胞周期依赖性激酶抑制相关蛋白抗体
英文名称Anti-P15RS/FITC
中文名称FITC标记的细胞周期依赖性激酶抑制相关蛋白抗体
别 名Cyclin dependent kinase 2B inhibitor related protein; Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein); Cyclin dependent kinase inhibitor 2B related protein; Cyclin dependent kinase inhibitor related protein; Hypothetical protein FLJ10656; p15INK4B related protein; Putative uncharacterized protein P15RS; Regulation of nuclear pre mRNA domain containing 1A; RPRD1A; RPR1A_HUMAN.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域细胞生物 细胞周期蛋白 激酶和磷酸酶 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Horse,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量36kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RPRD1A/P15RS
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and may have a role in cell cycle regulation 

Function:
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.

Subunit:
Associates with the RNA polymerase II complex.

Similarity:
Belongs to the UPF0400 (RTT103) family.
Contains 1 CID domain. 

Database links:

Entrez Gene: 420953 Chicken

Entrez Gene: 504355 Cow

Entrez Gene: 55197 Human

Entrez Gene: 225283 Mouse

Omim: 610347 Human

SwissProt: Q5ZM30 Chicken

SwissProt: Q0P5J9 Cow

SwissProt: Q96P16 Human

SwissProt: Q8VDS4 Mouse

Unigene: 464912 Human

Unigene: 28427 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.