本公司提供科研ZPI/SERPINA10丝氨酸蛋白酶抑制剂A10抗体，抗体质量可靠，订购ZPI/SERPINA10丝氨酸蛋白酶抑制剂A10抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：丝氨酸蛋白酶抑制剂A10抗体
英文名称：Anti-ZPI/SERPINA10
货号：bs-9209R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 51kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：ZPI, also known as SERPINA10 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10) or PZI, is a 444 amino acid secreted protein that functions as a Protein Z-dependent protease inhibitor. Expressed by the liver, ZPI is secreted into the plasma where, in the presence of calcium, Protein Z and phospholipids, it inhibits the activated pro-coagulation factors X and XI (Factor X and Factor XI). This inhibition helps properly regulate intravenous blood clotting. ZPI, a member of the serpin protein family, contains five potential N-linked glycosylation sites and a tyrosine at position 387 which, when disrupted, renders ZPI inactive. Defects in the gene encoding ZPI may increase susceptibility to venous thrombosis, the formation of blood clots within a vein.Subcellular Location : Secreted.Tissue Specificity : Expressed by the liver and secreted in plasma.