本公司提供科研KIF3A驱动蛋白家族蛋白3抗体，抗体质量可靠，订购KIF3A驱动蛋白家族蛋白3抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：驱动蛋白家族蛋白3抗体
英文名称：Anti-KIF3A
货号：bs-11211R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 80kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, hrs, pig, dog, cow, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.Function : Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.Subunit : Belongs to the kinesin-like protein family. Kinesin II subfamily.Contains 1 kinesin-motor domain.Subcellular Location : Cytoplasm, cytoskeleton (Probable). Cell projection, cilium (By similarity).Similarity : Belongs to the kinesin-like protein family. Kinesin II subfamily.Contains 1 kinesin-motor domain.