NCBI Gene Id: 1072; 12631; 29271
Swissprot Id: P23528
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004] - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OASG01697

Jurkat

Western Blot using Jurkat