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TG6-10-1

CAS No. : 1415716-58-3

MCE 国际站：TG6-10-1

产品活性：TG6-10-1 是一种 EP2 拮抗剂, 低纳摩尔下有效作用于 EP2, 比作用于人 EP3, EP4 和 IP 受体选择性高 300, EP1 受体选择性高 100 倍的。

研究领域：GPCR/G Protein | Neuronal Signaling

作用靶点：5-HT Receptor | Prostaglandin Receptor

In Vitro: TG6-10-1 robustly blocks prostaglandin E2 (PGE2) (10 μM)-induced cAMP accumulation in a concentration-dependent manner in SH-SY5Y cells.

In Vivo: TG6-10-1 (5 mg/kg; i.p.; 4-30 hours) improves survival, accelerates recovery of lost weight, and improves functional recovery following status epilepticus (SE) .

相关产品：Covalent Screening Library Plus | Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | Neuronal Signaling Compound Library | Covalent Screening Library | Endocrinology Compound Library | Neurotransmitter Receptor Compound Library | Anti-Alzheimer's Disease Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Angiogenesis Related Compound Library | Prostaglandin E2 | Prostaglandin E1 | Harmine | Puerarin | SCH-23390 hydrochloride | Iloprost | GTS-21 dihydrochloride | PF-04418948 | Dihydroergotamine mesylate | Tranilast | Thioridazine hydrochloride | Risperidone | WAY-100635 Maleate | SB-269970 hydrochloride | U-46619 | Aripiprazole | Ketanserin | Amitriptyline hydrochloride | ONO-AE3-208 | Pimavanserin | Buspirone hydrochloride | E7046 | Trazodone hydrochloride | Cisapride | AH 6809 | Brexpiprazole | Latanoprost | Grapiprant | Lurasidone | Methiothepin mesylate

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