产品货号:jlcR12733
英文名称:PLP2
中文名称:蛋白脂质蛋白2抗体
别名:A4; A4 differentiation dependent protein; A4-LSB; A4LSB; differentiation dependent protein A4; Differentiation-dependent protein A4; Intestinal membrane A4 protein; MGC126187; PLP2; PLP2_HUMAN; proteolipid protein 2 (colonic epithelium enriched); Proteolipid protein 2.
研究领域:细胞生物信号转导细胞周期蛋白细胞分化
抗体来源:Rabbit
克隆类型:Polyclonal
交叉反应: Human, Mouse, Rat, Pig, Horse, Rabbit,
产品应用:ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量:17kDa
细胞定位:细胞膜
性状:Lyophilized or Liquid
浓度:1mg/ml
免疫原:KLH conjugated synthetic peptide derived from human PLP2:1-100/152
亚型:IgG
纯化方法:affinity purified by Protein A
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :PubMed
产品介绍:This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]
Function:
May play a role in cell differentiation in the intestinal epithelium.
Subcellular Location:
Membrane.
Tissue Specificity:
Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.
Similarity:
Contains 1 MARVEL domain.
SWISS:
Q04941
Gene ID:
5355
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
