表皮生长因子抗体(小鼠)产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

表皮生长因子抗体(小鼠)产品介绍

表皮生长因子是一种小肽,由53个氨基酸残基组成, 是类EGF大家族的一个成员,是一种多功能的生长因子,在体内体外都对多种组织细胞有强烈的促分裂作用。EGF同应答细胞表面的特异受体结合,一旦结合,便促进受体二聚化并使细胞质位点磷酸化。被激活的受体至少可与5种具有不同信号序列的蛋白结合,进行信号转导,在翻译水平上对蛋白质的合成起调节作用。此外EGF可提高细胞内DNA拓扑异构酶活性,也可促进一些与增殖有关的基因表达,如myc 、fos等。
EGF exerts its signals through the EGF Receptor and its hetero-oligomerization partners, members of the ErbB family. The Receptors are transmembrane tyrosine kinases which are activated as a consequence of ligand-induced dimerization. Every EGF molecule has two receptor-binding sites, so the activated ligand-receptor complex consists of two molecules of EGF and two receptor molecules. Receptor autophosphorylation activates the intrinsic kinase activity towards heterologous substrates, as well as creating docking sites for adapter proteins to bind and nucleate signaling complexes that activate the Ras, PI3 Kinase and PLC pathways. Overexpression of the EGF Receptor is typical in most solid tumors

xy-11305R RFC2复制激活因子C2抗体
xy-11273R REAB淋巴细胞受体相关蛋白抗体
xy-3023R phospho-RUNX1 (Ser249)磷酸化急性髓细胞白血病1蛋白抗体
xy-3551R RIPK3受体结合丝氨酸苏氨酸激酶3抗体
xym-0855M Insulin (1G11)胰岛素单克隆抗体
xy-3558R phospho-Rb (Ser249)磷酸化视网膜母细胞瘤相关蛋白1抗体
xy-3378R Phospho-Rb (Ser608)磷酸化视网膜母细胞瘤相关蛋白1抗体
xy-9452R RGS4精神分裂症相关蛋白9抗体
xy-6391R RPRD1A细胞周期依赖性激酶抑制相关蛋白抗体
xy-7682R RBM38RNA结合蛋白38抗体
xy-7692R Relaxin 1松弛肽/松弛素抗体
xy-7693R Renalase肾胺酶抗体
xy-9243R RNF20环指蛋白20抗体
xy-9322R RanBP1RAN结合蛋白1抗体
xy-3791R RAE1mRNA结合蛋白抗体
xy-2125R RNF126环指蛋白126抗体
xym-2025M RBC(G2H4)小鼠抗人红细胞单克隆抗体
xy-1501R TIG2视黄酸受体应答蛋白2抗体
xy-1504R RAP1A抗Rap1A抗体
xy-6703R RAB7RAS癌基因相关蛋白RAB7抗体
xy-7827R RCLc-Myc应答蛋白抗体
xy-8307R RAB6BRAS癌基因相关蛋白RAB6B抗体
xy-7826R RABGAP1Rab蛋白GTP酶激活蛋白1抗体
xy-5774R RELM beta结肠癌相关基因蛋白抗体（resistin-like β）
xy-5490R phospho-Ron(Tyr1238)磷酸化原癌基因c-Met相关酪氨酸激酶抗体
xy-9172R RNF6环指蛋白6抗体
xy-5972R Ribonuclease 6核糖核酸酶6抗体
xy-5683R Phospho-RASGRF1 (Ser929)磷酸化Ras特异性鸟嘌呤核苷酸释放因子1
xy-5657R phospho-RAD9(Ser380)磷酸化细胞周期检查控制蛋白质抗体
表皮生长因子抗体(小鼠)