A small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity. PI3K inhibitor PX-866 inhibits the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.



Optical purity: 100% by chiral HPLC
Chemical Purity: >99% by HPLC


欢迎来到www.activebiochem-china.com(Active Biochem中国)。 我们是Active Biochem在中国的官方授权经销商，Active Biochem是全球生物活性试剂行业中的领导者之一。

Active Biochem公司是由一群优秀的化学家、药理学家和临床医生组成的团队建立,专注于提供最新的生物医学研究所需的工具。