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| 数量 | 大量 |
| 英文名 | Recombinant Murine GM-CSF |
| 保质期 | 一年 |
| 供应商 | 上海联迈生物工程有限公司 |
| 保存条件 | -20℃或更低温度保存 |
| 规格 | 5μg |
| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| LM6006-5μg | Recombinant Murine GM-CSF | 5μg | 464.00元 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Mouse | 12981 | LM01587 | E. coli | 124aa | 14.1kDa | － |
| About this Antibody | |
| Name | Recombinant Murine GM-CSF (Recombinant Murine Granulocyte-Macrophage Colony Stimulating Factor; rMuGM-CSF)；Recombinant Mouse GM-CSF ; 重组小鼠粒细胞巨噬细胞集落刺激因子 |
| Synonyms | CSF2; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; GM-CSF; GMCSFgranulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; Molgramostin; molgramostin; sargramostim; Sargramostim |
| Purity | >98% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine FDC-P1 cells is less than 0.05ng/ml, corresponding to a specific activity of >2.0×107IU/mg. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered solution in PBS, pH7.4. |
| Endotoxin | Less than 1EU/μg of rMuGM-CSF as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is secreted by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation. It was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors and has functions of stimulates the growth and differentiation of hematopoietic precursor cells from various lineages. GM-CSF has also been reported to have a functional role on non-hematopoietic cells and can induce human endothelial cells to migrate and proliferate. Additionally, it can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. Mouse GM-CSF shares 54% sequences identity with human GM-CSF, but has no biological effects across species. GM-CSF is used as a medication to stimulate the production of white blood cells following chemotherapy and has also recently been evaluated in clinical trials for its potential as a vaccine adjuvant in HIV-infected patients. |
| Amino Acid Sequence | APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK PGQK |
| 产品编号 | 产品名称 | 包装 |
| LM6006-5μg | Recombinant Murine GM-CSF | 5μg |
| LM6006-20μg | Recombinant Murine GM-CSF | 20μg |
| LM6006-100μg | Recombinant Murine GM-CSF | 100μg |
| LM6006-1mg | Recombinant Murine GM-CSF | 1mg |
| - | 说明书 | 1份 |
