关键词：NF2;神经纤维瘤蛋白2 ;神经纤维瘤蛋白2 ;NF2; SCH; Merlin; Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin

中文名称：神经纤维瘤蛋白2 (phospho Ser518)多克隆抗体/NF2 (phospho Ser518) Polyclonal Antibody

英文名称：NF2 (phospho Ser518) Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP55364.pdf

产品描述：兔抗-神经纤维瘤蛋白2 (phospho Ser518) 多克隆抗体

NF2 encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

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