产品名称：Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组-Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant

产品货号：P1128-50产品规格：50ug来源宿主：待更新保存建议：Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组-Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant-20°C背景资料：Low-Density Lipoprotein (LDL) Receptor is also known as LDLR, FH, FHC, LDLCQ2, and is a mosaic protein of ~840 amino acids (after removal of signal peptide) that mediates the endocytosis of cholesterol-rich LDL. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants (IDL). It belongs to the Low density lipoprotein receptor gene family. LDL receptor complexes are present in clathrin-coated pits (or buds) on the cell surface, which when bound to LDL-cholesterol via adaptin, are pinched off to form clathrin-coated vesicles inside the cell. This allows LDL-cholesterol to be bound and internalized in a process known as endocytosis and prevents the LDL just diffusing around the membrane surface. This occurs in all nucleated cells (not erythrocytes), but mainly in the liver which removes ~70% of LDL from the circulation. Synthesis of receptors in the cell is regulated by the level of free intracellular cholesterol; if it is in excess for the needs of the cell then the transcription of the receptor gene will be inhibited. LDL receptors are translated by ribosomes on the endoplasmic reticulum and are modified by the Golgi apparatus before travelling in vesicles to the cell surface. LDL is directly involved in the development of atherosclerosis, due to accumulation of LDL-cholesterol in the blood. Atherosclerosis is the process responsible for the majority of cardiovascular diseases.点击：Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组-Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.艾美捷科技有限公司，通过提供完整的产品和服务体系、便利的客户关系和供应链管理，为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观：“激情、敬业、学习、创新、合作、卓越”。激发我们内在的创造力，提供有竞争力的生物医学产品和服务，持续为客户创造最大价值是我们的企业使命。我们的企业愿景是成为受人尊重、世界知名的生物医学产品及服务供应商。艾美捷科技与国内外优秀的生物试剂供应商保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：AmyJet、AAT Bioquest、Abnova、Agrisera、Biovision、Biosensis、Cayman Chemical、Caisson Labs、Cytoskeleton、CytoNiChe、Epigentek、Equitech-Bio、Hycult Biotech、Jackson、LifeSensors、ProSpec、Norgen Biotek、Mabtech、Matreya、iRegene、StressMarq、ImmunoReagents、SouthernBiotech、Origene、US Biological、Solis BioDyne等，可以在第一时间为用户提供最前沿的专业资讯、完备的产品及物流服务。艾美捷服务升级，全方位实验服务项目上线啦~关键词：Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant/Human CellExp™ LDL R, Fc Tag, Human recombinant，Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组/Human CellExp™LDL R，Fc标签，人类重组，LDLR, FH, FHC, LDLCQ2