【Molecular Wt.】45 kDa

【Description】Over 100 cell surface markers have been identified through the use of monoclonal antibodies. Many of these markers have proven useful in identifying specific subpopulations of cells within mixed colonies. Accordingly, these molecules have been assigned a "cluster of differentiation" (CD) designation. One such marker, designated Thy-1 (also referred to as CDw90), is a phosphatidyl-anchored cell surface glycoprotein which, when coexpressed with CD34 on cells from normal human bone marrow, identifies a subpopulation that includes putative hematopoietic, pleuripotent stem cells. Thy-1+ cells from bone marrow have been implicated in syngeneic graft versus host disease and may serve to regulate autoreactivity after bone marrow transplant.

【Species Reactivity】Human

【Tested applications】WB;ICC/IF;IHC

【Antibody type】Recombinant Rabbit monoclonal Antibody

【Immunogen】recombinant protein

【Positive control】HUVEC, MCF-7, Hela, HepG2, PC-12, human tonsil tissue, human lung cancer tissue, human spleen tissue, human kidney tissue.

【Conjugate】Non-conjugated

【Alternative names】CD7 antibody
CD90 antibody
CD90 antigen antibody
CDw90 antibody
FLJ33325 antibody
MGC128895 antibody
T25 antibody
Theta antigen antibody
Thy 1 antibody
Thy 1 cell surface antigen antibody
Thy 1 membrane glycoprotein antibody
Thy 1 T cell antigen antibody
Thy 1.2 antibody
Thy-1 antigen antibody
Thy-1 membrane glycoprotein antibody
Thy1 antibody
Thy1 antigen antibody
Thy1 T cell antigen antibody
Thy1.1 antibody
Thy1.2 antibody
THY1_HUMAN antibody
Thymus cell antigen 1, theta antibody

【Form】Liquid

【Stroage】Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

【Stroage Buffer】1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

【Isotype】IgG

【Purity】Protein A purified.

【Subcellular location】Cell membrane.

【Background References】1. Chen WC et al. Cancer stem cell marker CD90 inhibits ovarian cancer formation via 3 integrin. Int J Oncol 49:1881-1889 (2016).
2. Du M et al. Acellular dermal matrix loading with bFGF achieves similar acceleration of bone regeneration to BMP-2 via differential effects on recruitment, proliferation and sustained osteodifferentiation of mesenchymal stem cells. Mater Sci Eng C Mater Biol Appl 70:62-70 (2017).

【DatasheetURL】http://www.huabio.com/upload/ET1702-92.pdf

【Uniprot ID】P04216(Human)

【Raised in】Rabbit

【Clone No.】JF10-09