FITC标记的囊泡相关膜蛋白2抗体

¥2980
LMAI Bio
中国/美国/欧洲
2022-03-25 12:27

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-1951R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-VAMP2/FITC
抗体名Anti-VAMP2/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
适应物种Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的囊泡相关膜蛋白2抗体
英文名称Anti-VAMP2/FITC
中文名称FITC标记的囊泡相关膜蛋白2抗体
别 名Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobrevin 2; VAMP 2; VAMP-2; Vesicle associated membrane protein 2; Vesicle-associated membrane protein 2; VAMP2_HUMAN; Synaptobrevin-2.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域肿瘤 神经生物学 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量13kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human VAMP-2 (76-116aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008].

Function:
Involved in the targeting and/or fusion of transport vesicles to their target membrane.

Subunit:
Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Interacts with BVES and STX4 (By similarity). Interacts with Vnd VAPB.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Note=Neuronal synaptic vesicles.

Tissue Specificity:
Nervous system and skeletal muscle.

Similarity:
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.

Database links:

Entrez Gene: 6844 Human

Entrez Gene: 22318 Mouse

Entrez Gene: 24803 Rat

Omim: 185881 Human

SwissProt: P63027 Human

SwissProt: P63044 Mouse

SwissProt: P63045 Rat

Unigene: 25348 Human

Unigene: 28643 Mouse

Unigene: 12939 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

VAMP-2是真核生物中的一种膜受体蛋白,该蛋白在真核生物的胞吐、信号传导、胞内运输和分泌等活动中起到重要作用.