FITC标记的癌症亮氨酸拉链下调因子1抗体

¥2980
LMAI Bio
中国/美国/欧洲
2022-03-25 21:38

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-6543R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-LDOC1/FITC
抗体名Anti-LDOC1/FITC
标记物FITC标记
宿主Human, Dog, Pig, Horse, Rabbit,
适应物种Human, Dog, Pig, Horse, Rabbit,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的癌症亮氨酸拉链下调因子1抗体
英文名称Anti-LDOC1/FITC
中文名称FITC标记的癌症亮氨酸拉链下调因子1抗体
别 名BCUR1; Breast cancer up regulated 1; Breast cancer upregulated 1; Gm366; Leucine zipper down regulated in cancer 1; Leucine zipper protein down regulated in cancer cells; Leucine zipper protein down regulated in cancer cells; Mar7; Mart7; Protein LDOC1; RGD1565644; LDOC1_HUMAN .
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域肿瘤 染色质和核信号 信号转导 转录调节因子 肿瘤细胞生物标志物 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Dog, Pig, Horse, Rabbit,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量17kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human LDOC1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]. 

Function:
May have an important role in the development and/or progression of some cancers.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitously expressed with high levels in brain and thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined.

Similarity:
Belongs to the LDOC1 family.

Database links:

Entrez Gene: 23641 Human

Omim: 300402 Human

SwissProt: O95751 Human

Unigene: 45231 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.