\n 产品概述:Purified recombinant protein of Mouse interferon dependent positive acting transcription factor 3 gamma (cDNA clone MGC:5974 IMAGE:3601255), complete, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
蛋白长度:A DNA sequence from Mouse cDNA ORF Clone, [GM35768V], encoding Mouse full-length Irf9.
表达系统:HEK293T
种属:Mouse
标签类型:C-MYC/DDK
分子量:85.8 kDa
通用名:Isgf3g
总结:Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.[UniProtKB/Swiss-Prot Function]
形式:Liquid
浓度:>50 ug/mL as determined by microplate BCA method
纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining
储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
别名:p48, Irf-9