Isgf3g (BC005435) Mouse Recombinant Protein

¥7106
LeadingBiology
美国
2022-07-02 10:16

安诺伦(北京)生物科技有限公司

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\n 产品概述:Purified recombinant protein of Mouse interferon dependent positive acting transcription factor 3 gamma (cDNA clone MGC:5974 IMAGE:3601255), complete, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

蛋白长度:A DNA sequence from Mouse cDNA ORF Clone, [GM35768V], encoding Mouse full-length Irf9.

表达系统:HEK293T

种属:Mouse

标签类型:C-MYC/DDK

分子量:85.8 kDa

通用名:Isgf3g

总结:Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.[UniProtKB/Swiss-Prot Function]

形式:Liquid

浓度:>50 ug/mL as determined by microplate BCA method

纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

别名:p48, Irf-9