\n

\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t

英文名称\xa0 Anti-IGFBP5/IBP5\xa0

中文名称\xa0 胰岛素样生长因子结合蛋白5抗体\xa0

别\xa0\xa0\xa0 名\xa0 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.\xa0

浓\xa0\xa0\xa0 度\xa0 1mg/1ml\xa0

规 格\xa0 0.1ml/100μg\xa0 0.2ml/200μg\xa0\xa0\xa0\xa0\xa0

抗体来源\xa0 Rabbit\xa0\xa0

克隆类型\xa0 polyclonal\xa0

交叉反应\xa0 Human, Mouse, Rat, Dog, Pig, Cow, Sheep

产品类型\xa0 一抗\xa0\xa0\xa0\xa0

研究领域\xa0 肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子 糖尿病\xa0\xa0 \t\t\t

蛋白分子量\xa0 predicted molecular weight: 30kDa\xa0

性\xa0\xa0\xa0 状\xa0 Lyophilized or Liquid\xa0

免 疫 原\xa0 KLH conjugated synthetic peptide derived from human IGFBP5(101-200aa)\xa0

亚\xa0\xa0\xa0 型\xa0 IgG\xa0

纯化方法\xa0 affinity purified by Protein A\xa0

储 存 液\xa0 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide\xa0

产品应用\xa0\xa0 WB=1:100-500\xa0 ELISA=1:500-1000\xa0 IP=1:20-100\xa0 IHC-P=1:100-500\xa0 IHC-F=1:100-500\xa0 IF=1:100-500\xa0

（石蜡切片需做抗原修复）\xa0

\xa0not yet tested in other applications.

\xa0optimal dilutions/concentrations should be determined by the end user.\xa0\xa0

保存条件\xa0 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\xa0 \t\t\t

Important Note\xa0 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0

产品介绍 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.

Function : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Subcellular Location : Secreted.

Tissue Specificity : Osteosarcoma, and at lower levels in liver, kidney and brain.

Similarity : Contains 1 IGFBP N-terminal domain.

Contains 1 thyroglobulin type-1 domain.

Database links : UniProtKB/Swiss-Prot: P24593.1

生长因子和激素（ Growth Factor and Hormones）

IGFBP5胰岛素样生长因子结合蛋白5(IGFBP-5)是一种可以与胰岛素样生长因子(IGFs)结合的分泌性蛋白,其通过IGFs调节细胞的生长、分化、凋亡、黏附和运动,IGFBP-5与IGFs结合可以调节IGFs与IGF-I型受体间的相互作用,改变其促有丝分裂效应、凋亡抑制效应和促细胞运动作用。

有人认为：由于造骨细胞能表达与IGF-1受体截然不同的IGFBP-5受体，IGFBP-5本身也是一种生长因子，能够不依赖IGF-I独立作用来调节骨代谢。 \t\t\t \t\t\t\xa0

IRS-2 \xa0\xa0胰岛素受体底物-2（抗原）

IRS-3\xa0\xa0胰岛素受体底物-3（抗原）

IRS-4\xa0\xa0胰岛素受体底物-4（抗原）

IRS P53 (Insulin receptor suYTtrate P53)(多肽）\xa0\xa0

ITG-β3(Integrin β chain,β3 precursor)\xa0\xa0整合素-β3（抗原）

Leptin\xa0\xa0瘦素（多肽抗原）

Leptin receptor（long）\xa0\xa0瘦素受体（长）（抗原）

MAPK-1/2\xa0\xa0丝裂原活化蛋白激酶（抗原）

MAPKK2\xa0\xa0丝裂原活化蛋白激酶激酶

M2-PK （ pyruvate Kinase M2）\xa0\xa0丙-酮酸激酶-M2（抗原）

M2-PK （ pyruvate Kinase M2 ） \xa0\xa0丙-酮酸激酶-M2（抗原）

Melan-A/MART-1\xa0\xa0黑色素-A（抗原）

ARIP2a（Activin receptor 2A）\xa0\xa0激活素受体2A/激活素受体相互作用蛋白2a抗原

β-arrestin 1/2(beta-arrestin 1/2)\xa0\xa0β-抑制蛋白1/2抗原

ARIP2B（Activin receptor 2B）\xa0\xa0激活素受体2B/激活素受体相互作用蛋白2b抗体

MTR-1A (Melatonin receptor-1A)\xa0\xa0褪黑素受体（抗原）

MTLC (c-Myc target from laryngeal cancer cells)又称：MYC\xa0\xa0致癌基因（抗原）

N-coR1 （Nuclear receptor co-repressor 1） \xa0\xa0核受体辅助抑制因子（抗原）

\t\t\t\t\t\t\t\t\t\t\t\t\t英文名称\xa0 Anti-IGFBP5/IBP5\xa0\t\t\t\t\t\t\t中文名称\xa0 胰岛素样生长因子结合蛋白5抗体\xa0\t\t\t\t\t\t\t别\xa0\xa0\xa0 名\xa0 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.\xa0\t\t\t\t\t\t\t浓\xa0\xa0\xa0 度\xa0 1mg/1ml\xa0\t\t\t\t\t\t\t规 格\xa0 0.1ml/100μg\xa0 0.2ml/200μg\xa0\xa0\xa0\xa0\xa0\t\t\t\t\t\t\t抗体来源\xa0 Rabbit\xa0\xa0\t\t\t\t\t\t\t克隆类型\xa0 polyclonal\xa0\t\t\t\t\t\t\t交叉反应\xa0 Human, Mouse, Rat, Dog, Pig, Cow, Sheep\t\t\t\t\t\t\t产品类型\xa0 一抗\xa0\xa0\xa0\xa0\t\t\t\t\t\t\t研究领域\xa0 肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子 糖尿病\xa0\xa0
\t\t\t\t\t\t\t\t\t\t蛋白分子量\xa0 predicted molecular weight: 30kDa\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0 状\xa0 Lyophilized or Liquid\xa0\t\t\t\t\t\t\t免 疫 原\xa0 KLH conjugated synthetic peptide derived from human IGFBP5(101-200aa)\xa0\t\t\t\t\t\t\t亚\xa0\xa0\xa0 型\xa0 IgG\xa0\t\t\t\t\t\t\t纯化方法\xa0 affinity purified by Protein A\xa0\t\t\t\t\t\t\t储 存 液\xa0 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide\xa0\t\t\t\t\t\t\t产品应用\xa0\xa0 WB=1:100-500\xa0 ELISA=1:500-1000\xa0 IP=1:20-100\xa0 IHC-P=1:100-500\xa0 IHC-F=1:100-500\xa0 IF=1:100-500\xa0\t\t\t\t\t\t\t（石蜡切片需做抗原修复）\xa0\t\t\t\t\t\t\t\xa0not yet tested in other applications.\t\t\t\t\t\t\t\xa0optimal dilutions/concentrations should be determined by the end user.\xa0\xa0\t\t\t\t\t\t\t保存条件\xa0 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\xa0
\t\t\t\t\t\t\t\t\t\tImportant Note\xa0 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0\t\t\t\t\t\t\t产品介绍 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.\t\t\t\t\t\t\tFunction : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.\t\t\t\t\t\t\tSubcellular Location : Secreted.\t\t\t\t\t\t\tTissue Specificity : Osteosarcoma, and at lower levels in liver, kidney and brain.\t\t\t\t\t\t\tSimilarity : Contains 1 IGFBP N-terminal domain.\t\t\t\t\t\t\tContains 1 thyroglobulin type-1 domain.\t\t\t\t\t\t\tDatabase links : UniProtKB/Swiss-Prot: P24593.1\t\t\t\t\t\t\t生长因子和激素（ Growth Factor and Hormones）\t\t\t\t\t\t\tIGFBP5胰岛素样生长因子结合蛋白5(IGFBP-5)是一种可以与胰岛素样生长因子(IGFs)结合的分泌性蛋白,其通过IGFs调节细胞的生长、分化、凋亡、黏附和运动,IGFBP-5与IGFs结合可以调节IGFs与IGF-I型受体间的相互作用,改变其促有丝分裂效应、凋亡抑制效应和促细胞运动作用。\t\t\t\t\t\t\t有人认为：由于造骨细胞能表达与IGF-1受体截然不同的IGFBP-5受体，IGFBP-5本身也是一种生长因子，能够不依赖IGF-I独立作用来调节骨代谢。
\t\t\t
\t\t\t\xa0\t\t\t\t\t\t\tIRS-2 \xa0\xa0胰岛素受体底物-2（抗原）\t\t\t\t\t\t\tIRS-3\xa0\xa0胰岛素受体底物-3（抗原）\t\t\t\t\t\t\tIRS-4\xa0\xa0胰岛素受体底物-4（抗原）\t\t\t\t\t\t\tIRS P53 (Insulin receptor suYTtrate P53)(多肽）\xa0\xa0\t\t\t\t\t\t\tITG-β3(Integrin β chain,β3 precursor)\xa0\xa0整合素-β3（抗原）\t\t\t\t\t\t\tLeptin\xa0\xa0瘦素（多肽抗原）\t\t\t\t\t\t\tLeptin receptor（long）\xa0\xa0瘦素受体（长）（抗原）\t\t\t\t\t\t\tMAPK-1/2\xa0\xa0丝裂原活化蛋白激酶（抗原）\t\t\t\t\t\t\tMAPKK2\xa0\xa0丝裂原活化蛋白激酶激酶\t\t\t\t\t\t\tM2-PK （ pyruvate Kinase M2）\xa0\xa0丙-酮酸激酶-M2（抗原）\t\t\t\t\t\t\tM2-PK （ pyruvate Kinase M2 ） \xa0\xa0丙-酮酸激酶-M2（抗原）\t\t\t\t\t\t\tMelan-A/MART-1\xa0\xa0黑色素-A（抗原）\t\t\t\t\t\t\tARIP2a（Activin receptor 2A）\xa0\xa0激活素受体2A/激活素受体相互作用蛋白2a抗原\t\t\t\t\t\t\tβ-arrestin 1/2(beta-arrestin 1/2)\xa0\xa0β-抑制蛋白1/2抗原\t\t\t\t\t\t\tARIP2B（Activin receptor 2B）\xa0\xa0激活素受体2B/激活素受体相互作用蛋白2b抗体\t\t\t\t\t\t\tMTR-1A (Melatonin receptor-1A)\xa0\xa0褪黑素受体（抗原）\t\t\t\t\t\t\tMTLC (c-Myc target from laryngeal cancer cells)又称：MYC\xa0\xa0致癌基因（抗原）\t\t\t\t\t\t\tN-coR1 （Nuclear receptor co-repressor 1） \xa0\xa0核受体辅助抑制因子（抗原）\t\t\t\t\t\t\t\t英文名称\xa0 Anti-IGFBP5/IBP5\xa0\t\t\t\t\t英文名称\xa0 Anti-IGFBP5/IBP5\xa0英文名称\xa0 Anti-IGFBP5/IBP5\xa0英文名称\xa0 Anti-IGFBP5/IBP5\xa0英文名称\xa0 Anti-IGFBP5/IBP5\xa0\t\t\t\t\t\t\t中文名称\xa0 胰岛素样生长因子结合蛋白5抗体\xa0\t\t\t\t\t中文名称\xa0 胰岛素样生长因子结合蛋白5抗体\xa0中文名称\xa0 胰岛素样生长因子结合蛋白5抗体\xa0中文名称\xa0 胰岛素样生长因子结合蛋白5抗体\xa0中文名称\xa0 胰岛素样生长因子结合蛋白5抗体\xa0\t\t\t\t\t\t\t别\xa0\xa0\xa0 名\xa0 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.\xa0\t\t\t\t\t别\xa0\xa0\xa0 名\xa0 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.\xa0别\xa0\xa0\xa0 名\xa0 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.\xa0别\xa0\xa0\xa0 名\xa0 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.\xa0别\xa0\xa0\xa0 名\xa0 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.\xa0\t\t\t\t\t\t\t浓\xa0\xa0\xa0 度\xa0 1mg/1ml\xa0\t\t\t\t\t浓\xa0\xa0\xa0 度\xa0 1mg/1ml\xa0浓\xa0\xa0\xa0 度\xa0 1mg/1ml\xa0浓\xa0\xa0\xa0 度\xa0 1mg/1ml\xa0浓\xa0\xa0\xa0 度\xa0 1mg/1ml\xa0\t\t\t\t\t\t\t规 格\xa0 0.1ml/100μg\xa0 0.2ml/200μg\xa0\xa0\xa0\xa0\xa0\t\t\t\t\t规 格\xa0 0.1ml/100μg\xa0 0.2ml/200μg\xa0\xa0\xa0\xa0\xa0规 格\xa0 0.1ml/100μg\xa0 0.2ml/200μg\xa0\xa0\xa0\xa0\xa0规 格\xa0 0.1ml/100μg\xa0 0.2ml/200μg\xa0\xa0\xa0\xa0\xa0规 格\xa0 0.1ml/100μg\xa0 0.2ml/200μg\xa0\xa0\xa0\xa0\xa0\t\t\t\t\t\t\t抗体来源\xa0 Rabbit\xa0\xa0\t\t\t\t\t抗体来源\xa0 Rabbit\xa0\xa0抗体来源\xa0 Rabbit\xa0\xa0抗体来源\xa0 Rabbit\xa0\xa0抗体来源\xa0 Rabbit\xa0\xa0\t\t\t\t\t\t\t克隆类型\xa0 polyclonal\xa0\t\t\t\t\t克隆类型\xa0 polyclonal\xa0克隆类型\xa0 polyclonal\xa0克隆类型\xa0 polyclonal\xa0克隆类型\xa0 polyclonal\xa0\t\t\t\t\t\t\t交叉反应\xa0 Human, Mouse, Rat, Dog, Pig, Cow, Sheep\t\t\t\t\t交叉反应\xa0 Human, Mouse, Rat, Dog, Pig, Cow, Sheep交叉反应\xa0 Human, Mouse, Rat, Dog, Pig, Cow, Sheep交叉反应\xa0 Human, Mouse, Rat, Dog, Pig, Cow, Sheep交叉反应\xa0 Human, Mouse, Rat, Dog, Pig, Cow, Sheep\t\t\t\t\t\t\t产品类型\xa0 一抗\xa0\xa0\xa0\xa0\t\t\t\t\t产品类型\xa0 一抗\xa0\xa0\xa0\xa0产品类型\xa0 一抗\xa0\xa0\xa0\xa0产品类型\xa0 一抗\xa0\xa0\xa0\xa0产品类型\xa0 一抗\xa0\xa0\xa0\xa0\t\t\t\t\t\t\t研究领域\xa0 肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子 糖尿病\xa0\xa0
\t\t\t\t\t\t\t\t研究领域\xa0 肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子 糖尿病\xa0\xa0
\t\t\t研究领域\xa0 肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子 糖尿病\xa0\xa0
\t\t\t研究领域\xa0 肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子 糖尿病\xa0\xa0
\t\t\t研究领域\xa0 肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子 糖尿病\xa0\xa0
\t\t\t\t\t\t\t\t\t\t蛋白分子量\xa0 predicted molecular weight: 30kDa\xa0\t\t\t\t\t蛋白分子量\xa0 predicted molecular weight: 30kDa\xa0蛋白分子量\xa0 predicted molecular weight: 30kDa\xa0蛋白分子量\xa0 predicted molecular weight: 30kDa\xa0蛋白分子量\xa0 predicted molecular weight: 30kDa\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0 状\xa0 Lyophilized or Liquid\xa0\t\t\t\t\t性\xa0\xa0\xa0 状\xa0 Lyophilized or Liquid\xa0性\xa0\xa0\xa0 状\xa0 Lyophilized or Liquid\xa0性\xa0\xa0\xa0 状\xa0 Lyophilized or Liquid\xa0性\xa0\xa0\xa0 状\xa0 Lyophilized or Liquid\xa0\t\t\t\t\t\t\t免 疫 原\xa0 KLH conjugated synthetic peptide derived from human IGFBP5(101-200aa)\xa0\t\t\t\t\t免 疫 原\xa0 KLH conjugated synthetic peptide derived from human IGFBP5(101-200aa)\xa0免 疫 原\xa0 KLH conjugated synthetic peptide derived from human IGFBP5(101-200aa)\xa0免 疫 原\xa0 KLH conjugated synthetic peptide derived from human IGFBP5(101-200aa)\xa0免 疫 原\xa0 KLH conjugated synthetic peptide derived from human IGFBP5(101-200aa)\xa0\t\t\t\t\t\t\t亚\xa0\xa0\xa0 型\xa0 IgG\xa0\t\t\t\t\t亚\xa0\xa0\xa0 型\xa0 IgG\xa0亚\xa0\xa0\xa0 型\xa0 IgG\xa0亚\xa0\xa0\xa0 型\xa0 IgG\xa0亚\xa0\xa0\xa0 型\xa0 IgG\xa0\t\t\t\t\t\t\t纯化方法\xa0 affinity purified by Protein A\xa0\t\t\t\t\t纯化方法\xa0 affinity purified by Protein A\xa0纯化方法\xa0 affinity purified by Protein A\xa0纯化方法\xa0 affinity purified by Protein A\xa0纯化方法\xa0 affinity purified by Protein A\xa0\t\t\t\t\t\t\t储 存 液\xa0 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide\xa0\t\t\t\t\t储 存 液\xa0 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide\xa0储 存 液\xa0 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide\xa0储 存 液\xa0 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide\xa0储 存 液\xa0 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide\xa0\t\t\t\t\t\t\t产品应用\xa0\xa0 WB=1:100-500\xa0 ELISA=1:500-1000\xa0 IP=1:20-100\xa0 IHC-P=1:100-500\xa0 IHC-F=1:100-500\xa0 IF=1:100-500\xa0\t\t\t\t\t产品应用\xa0\xa0 WB=1:100-500\xa0 ELISA=1:500-1000\xa0 IP=1:20-100\xa0 IHC-P=1:100-500\xa0 IHC-F=1:100-500\xa0 IF=1:100-500\xa0产品应用\xa0\xa0 WB=1:100-500\xa0 ELISA=1:500-1000\xa0 IP=1:20-100\xa0 IHC-P=1:100-500\xa0 IHC-F=1:100-500\xa0 IF=1:100-500\xa0产品应用\xa0\xa0 WB=1:100-500\xa0 ELISA=1:500-1000\xa0 IP=1:20-100\xa0 IHC-P=1:100-500\xa0 IHC-F=1:100-500\xa0 IF=1:100-500\xa0产品应用\xa0\xa0 WB=1:100-500\xa0 ELISA=1:500-1000\xa0 IP=1:20-100\xa0 IHC-P=1:100-500\xa0 IHC-F=1:100-500\xa0 IF=1:100-500\xa0\t\t\t\t\t\t\t（石蜡切片需做抗原修复）\xa0\t\t\t\t\t（石蜡切片需做抗原修复）\xa0（石蜡切片需做抗原修复）\xa0（石蜡切片需做抗原修复）\xa0（石蜡切片需做抗原修复）\xa0\t\t\t\t\t\t\t\xa0not yet tested in other applications.\t\t\t\t\t\xa0not yet tested in other applications.\xa0not yet tested in other applications.\xa0not yet tested in other applications.\xa0not yet tested in other applications.\t\t\t\t\t\t\t\xa0optimal dilutions/concentrations should be determined by the end user.\xa0\xa0\t\t\t\t\t\xa0optimal dilutions/concentrations should be determined by the end user.\xa0\xa0\xa0optimal dilutions/concentrations should be determined by the end user.\xa0\xa0\xa0optimal dilutions/concentrations should be determined by the end user.\xa0\xa0\xa0optimal dilutions/concentrations should be determined by the end user.\xa0\xa0\t\t\t\t\t\t\t保存条件\xa0 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\xa0
\t\t\t\t\t\t\t\t保存条件\xa0 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\xa0
\t\t\t保存条件\xa0 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\xa0
\t\t\t保存条件\xa0 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\xa0
\t\t\t保存条件\xa0 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\xa0
\t\t\t\t\t\t\t\t\t\tImportant Note\xa0 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0\t\t\t\t\tImportant Note\xa0 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0Important Note\xa0 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0Important Note\xa0 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0Important Note\xa0 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0\t\t\t\t\t\t\t产品介绍 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.\t\t\t\t\t产品介绍 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.产品介绍 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.产品介绍 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.产品介绍 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.\t\t\t\t\t\t\tFunction : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.\t\t\t\t\tFunction : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.Function : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.Function : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.Function : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.\t\t\t\t\t\t\tSubcellular Location : Secreted.\t\t\t\t\tSubcellular Location : Secreted.Subcellular Location : Secreted.Subcellular Location : Secreted.Subcellular Location : Secreted.\t\t\t\t\t\t\tTissue Specificity : Osteosarcoma, and at lower levels in liver, kidney and brain.\t\t\t\t\tTissue Specificity : Osteosarcoma, and at lower levels in liver, kidney and brain.Tissue Specificity : Osteosarcoma, and at lower levels in liver, kidney and brain.Tissue Specificity : Osteosarcoma, and at lower levels in liver, kidney and brain.Tissue Specificity : Osteosarcoma, and at lower levels in liver, kidney and brain.\t\t\t\t\t\t\tSimilarity : Contains 1 IGFBP N-terminal domain.\t\t\t\t\tSimilarity : Contains 1 IGFBP N-terminal domain.Similarity : Contains 1 IGFBP N-terminal domain.Similarity : Contains 1 IGFBP N-terminal domain.Similarity : Contains 1 IGFBP N-terminal domain.\t\t\t\t\t\t\tContains 1 thyroglobulin type-1 domain.\t\t\t\t\tContains 1 thyroglobulin type-1 domain.Contains 1 thyroglobulin type-1 domain.Contains 1 thyroglobulin type-1 domain.Contains 1 thyroglobulin type-1 domain.\t\t\t\t\t\t\tDatabase links : UniProtKB/Swiss-Prot: P24593.1\t\t\t\t\tDatabase links : UniProtKB/Swiss-Prot: P24593.1Database links : UniProtKB/Swiss-Prot: P24593.1Database links : UniProtKB/Swiss-Prot: P24593.1Database links : UniProtKB/Swiss-Prot: P24593.1\t\t\t\t\t\t\t生长因子和激素（ Growth Factor and Hormones）\t\t\t\t\t生长因子和激素（ Growth Factor and Hormones）生长因子和激素（ Growth Factor and Hormones）生长因子和激素（ Growth Factor and Hormones）生长因子和激素（ Growth Factor and Hormones）\t\t\t\t\t\t\tIGFBP5胰岛素样生长因子结合蛋白5(IGFBP-5)是一种可以与胰岛素样生长因子(IGFs)结合的分泌性蛋白,其通过IGFs调节细胞的生长、分化、凋亡、黏附和运动,IGFBP-5与IGFs结合可以调节IGFs与IGF-I型受体间的相互作用,改变其促有丝分裂效应、凋亡抑制效应和促细胞运动作用。\t\t\t\t\tIGFBP5胰岛素样生长因子结合蛋白5(IGFBP-5)是一种可以与胰岛素样生长因子(IGFs)结合的分泌性蛋白,其通过IGFs调节细胞的生长、分化、凋亡、黏附和运动,IGFBP-5与IGFs结合可以调节IGFs与IGF-I型受体间的相互作用,改变其促有丝分裂效应、凋亡抑制效应和促细胞运动作用。IGFBP5胰岛素样生长因子结合蛋白5(IGFBP-5)是一种可以与胰岛素样生长因子(IGFs)结合的分泌性蛋白,其通过IGFs调节细胞的生长、分化、凋亡、黏附和运动,IGFBP-5与IGFs结合可以调节IGFs与IGF-I型受体间的相互作用,改变其促有丝分裂效应、凋亡抑制效应和促细胞运动作用。IGFBP5胰岛素样生长因子结合蛋白5(IGFBP-5)是一种可以与胰岛素样生长因子(IGFs)结合的分泌性蛋白,其通过IGFs调节细胞的生长、分化、凋亡、黏附和运动,IGFBP-5与IGFs结合可以调节IGFs与IGF-I型受体间的相互作用,改变其促有丝分裂效应、凋亡抑制效应和促细胞运动作用。IGFBP5胰岛素样生长因子结合蛋白5(IGFBP-5)是一种可以与胰岛素样生长因子(IGFs)结合的分泌性蛋白,其通过IGFs调节细胞的生长、分化、凋亡、黏附和运动,IGFBP-5与IGFs结合可以调节IGFs与IGF-I型受体间的相互作用,改变其促有丝分裂效应、凋亡抑制效应和促细胞运动作用。\t\t\t\t\t\t\t有人认为：由于造骨细胞能表达与IGF-1受体截然不同的IGFBP-5受体，IGFBP-5本身也是一种生长因子，能够不依赖IGF-I独立作用来调节骨代谢。
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\t\t\t\xa0\t\t\t\t\t有人认为：由于造骨细胞能表达与IGF-1受体截然不同的IGFBP-5受体，IGFBP-5本身也是一种生长因子，能够不依赖IGF-I独立作用来调节骨代谢。
\t\t\t
\t\t\t\xa0有人认为：由于造骨细胞能表达与IGF-1受体截然不同的IGFBP-5受体，IGFBP-5本身也是一种生长因子，能够不依赖IGF-I独立作用来调节骨代谢。
\t\t\t有人认为：由于造骨细胞能表达与IGF-1受体截然不同的IGFBP-5受体，IGFBP-5本身也是一种生长因子，能够不依赖IGF-I独立作用来调节骨代谢。
\t\t\t有人认为：由于造骨细胞能表达与IGF-1受体截然不同的IGFBP-5受体，IGFBP-5本身也是一种生长因子，能够不依赖IGF-I独立作用来调节骨代谢。
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\t\t\t\xa0\t\t\t\t\t\t\tIRS-2 \xa0\xa0胰岛素受体底物-2（抗原）\t\t\t\t\tIRS-2 \xa0\xa0胰岛素受体底物-2（抗原）IRS-2 \xa0\xa0胰岛素受体底物-2（抗原）IRS-2 \xa0\xa0胰岛素受体底物-2（抗原）IRS-2 \xa0\xa0胰岛素受体底物-2（抗原）\t\t\t\t\t\t\tIRS-3\xa0\xa0胰岛素受体底物-3（抗原）\t\t\t\t\tIRS-3\xa0\xa0胰岛素受体底物-3（抗原）IRS-3\xa0\xa0胰岛素受体底物-3（抗原）IRS-3\xa0\xa0胰岛素受体底物-3（抗原）IRS-3\xa0\xa0胰岛素受体底物-3（抗原）\t\t\t\t\t\t\tIRS-4\xa0\xa0胰岛素受体底物-4（抗原）\t\t\t\t\tIRS-4\xa0\xa0胰岛素受体底物-4（抗原）IRS-4\xa0\xa0胰岛素受体底物-4（抗原）IRS-4\xa0\xa0胰岛素受体底物-4（抗原）IRS-4\xa0\xa0胰岛素受体底物-4（抗原）\t\t\t\t\t\t\tIRS P53 (Insulin receptor suYTtrate P53)(多肽）\xa0\xa0\t\t\t\t\tIRS P53 (Insulin receptor suYTtrate P53)(多肽）\xa0\xa0IRS P53 (Insulin receptor suYTtrate P53)(多肽）\xa0\xa0IRS P53 (Insulin receptor suYTtrate P53)(多肽）\xa0\xa0IRS P53 (Insulin receptor suYTtrate P53)(多肽）\xa0\xa0\t\t\t\t\t\t\tITG-β3(Integrin β chain,β3 precursor)\xa0\xa0整合素-β3（抗原）\t\t\t\t\tITG-β3(Integrin β chain,β3 precursor)\xa0\xa0整合素-β3（抗原）ITG-β3(Integrin β chain,β3 precursor)\xa0\xa0整合素-β3（抗原）ITG-β3(Integrin β chain,β3 precursor)\xa0\xa0整合素-β3（抗原）ITG-β3(Integrin β chain,β3 precursor)\xa0\xa0整合素-β3（抗原）\t\t\t\t\t\t\tLeptin\xa0\xa0瘦素（多肽抗原）\t\t\t\t\tLeptin\xa0\xa0瘦素（多肽抗原）Leptin\xa0\xa0瘦素（多肽抗原）Leptin\xa0\xa0瘦素（多肽抗原）Leptin\xa0\xa0瘦素（多肽抗原）\t\t\t\t\t\t\tLeptin receptor（long）\xa0\xa0瘦素受体（长）（抗原）\t\t\t\t\tLeptin receptor（long）\xa0\xa0瘦素受体（长）（抗原）Leptin receptor（long）\xa0\xa0瘦素受体（长）（抗原）Leptin receptor（long）\xa0\xa0瘦素受体（长）（抗原）Leptin receptor（long）\xa0\xa0瘦素受体（长）（抗原）\t\t\t\t\t\t\tMAPK-1/2\xa0\xa0丝裂原活化蛋白激酶（抗原）\t\t\t\t\tMAPK-1/2\xa0\xa0丝裂原活化蛋白激酶（抗原）MAPK-1/2\xa0\xa0丝裂原活化蛋白激酶（抗原）MAPK-1/2\xa0\xa0丝裂原活化蛋白激酶（抗原）MAPK-1/2\xa0\xa0丝裂原活化蛋白激酶（抗原）\t\t\t\t\t\t\tMAPKK2\xa0\xa0丝裂原活化蛋白激酶激酶\t\t\t\t\tMAPKK2\xa0\xa0丝裂原活化蛋白激酶激酶MAPKK2\xa0\xa0丝裂原活化蛋白激酶激酶MAPKK2\xa0\xa0丝裂原活化蛋白激酶激酶MAPKK2\xa0\xa0丝裂原活化蛋白激酶激酶\t\t\t\t\t\t\tM2-PK （ pyruvate Kinase M2）\xa0\xa0丙-酮酸激酶-M2（抗原）\t\t\t\t\tM2-PK （ pyruvate Kinase M2）\xa0\xa0丙-酮酸激酶-M2（抗原）M2-PK （ pyruvate Kinase M2）\xa0\xa0丙-酮酸激酶-M2（抗原）M2-PK （ pyruvate Kinase M2）\xa0\xa0丙-酮酸激酶-M2（抗原）M2-PK （ pyruvate Kinase M2）\xa0\xa0丙-酮酸激酶-M2（抗原）\t\t\t\t\t\t\tM2-PK （ pyruvate Kinase M2 ） \xa0\xa0丙-酮酸激酶-M2（抗原）\t\t\t\t\tM2-PK （ pyruvate Kinase M2 ） \xa0\xa0丙-酮酸激酶-M2（抗原）M2-PK （ pyruvate Kinase M2 ） \xa0\xa0丙-酮酸激酶-M2（抗原）M2-PK （ pyruvate Kinase M2 ） \xa0\xa0丙-酮酸激酶-M2（抗原）M2-PK （ pyruvate Kinase M2 ） \xa0\xa0丙-酮酸激酶-M2（抗原）\t\t\t\t\t\t\tMelan-A/MART-1\xa0\xa0黑色素-A（抗原）\t\t\t\t\tMelan-A/MART-1\xa0\xa0黑色素-A（抗原）Melan-A/MART-1\xa0\xa0黑色素-A（抗原）Melan-A/MART-1\xa0\xa0黑色素-A（抗原）Melan-A/MART-1\xa0\xa0黑色素-A（抗原）\t\t\t\t\t\t\tARIP2a（Activin receptor 2A）\xa0\xa0激活素受体2A/激活素受体相互作用蛋白2a抗原\t\t\t\t\tARIP2a（Activin receptor 2A）\xa0\xa0激活素受体2A/激活素受体相互作用蛋白2a抗原ARIP2a（Activin receptor 2A）\xa0\xa0激活素受体2A/激活素受体相互作用蛋白2a抗原ARIP2a（Activin receptor 2A）\xa0\xa0激活素受体2A/激活素受体相互作用蛋白2a抗原ARIP2a（Activin receptor 2A）\xa0\xa0激活素受体2A/激活素受体相互作用蛋白2a抗原\t\t\t\t\t\t\tβ-arrestin 1/2(beta-arrestin 1/2)\xa0\xa0β-抑制蛋白1/2抗原\t\t\t\t\tβ-arrestin 1/2(beta-arrestin 1/2)\xa0\xa0β-抑制蛋白1/2抗原β-arrestin 1/2(beta-arrestin 1/2)\xa0\xa0β-抑制蛋白1/2抗原β-arrestin 1/2(beta-arrestin 1/2)\xa0\xa0β-抑制蛋白1/2抗原β-arrestin 1/2(beta-arrestin 1/2)\xa0\xa0β-抑制蛋白1/2抗原\t\t\t\t\t\t\tARIP2B（Activin receptor 2B）\xa0\xa0激活素受体2B/激活素受体相互作用蛋白2b抗体\t\t\t\t\tARIP2B（Activin receptor 2B）\xa0\xa0激活素受体2B/激活素受体相互作用蛋白2b抗体ARIP2B（Activin receptor 2B）\xa0\xa0激活素受体2B/激活素受体相互作用蛋白2b抗体ARIP2B（Activin receptor 2B）\xa0\xa0激活素受体2B/激活素受体相互作用蛋白2b抗体ARIP2B（Activin receptor 2B）\xa0\xa0激活素受体2B/激活素受体相互作用蛋白2b抗体\t\t\t\t\t\t\tMTR-1A (Melatonin receptor-1A)\xa0\xa0褪黑素受体（抗原）\t\t\t\t\tMTR-1A (Melatonin receptor-1A)\xa0\xa0褪黑素受体（抗原）MTR-1A (Melatonin receptor-1A)\xa0\xa0褪黑素受体（抗原）MTR-1A (Melatonin receptor-1A)\xa0\xa0褪黑素受体（抗原）MTR-1A (Melatonin receptor-1A)\xa0\xa0褪黑素受体（抗原）\t\t\t\t\t\t\tMTLC (c-Myc target from laryngeal cancer cells)又称：MYC\xa0\xa0致癌基因（抗原）\t\t\t\t\tMTLC (c-Myc target from laryngeal cancer cells)又称：MYC\xa0\xa0致癌基因（抗原）MTLC (c-Myc target from laryngeal cancer cells)又称：MYC\xa0\xa0致癌基因（抗原）MTLC (c-Myc target from laryngeal cancer cells)又称：MYC\xa0\xa0致癌基因（抗原）MTLC (c-Myc target from laryngeal cancer cells)又称：MYC\xa0\xa0致癌基因（抗原）\t\t\t\t\t\t\tN-coR1 （Nuclear receptor co-repressor 1） \xa0\xa0核受体辅助抑制因子（抗原）\t\t\t\t\tN-coR1 （Nuclear receptor co-repressor 1） \xa0\xa0核受体辅助抑制因子（抗原）N-coR1 （Nuclear receptor co-repressor 1） \xa0\xa0核受体辅助抑制因子（抗原）N-coR1 （Nuclear receptor co-repressor 1） \xa0\xa0核受体辅助抑制因子（抗原）N-coR1 （Nuclear receptor co-repressor 1） \xa0\xa0核受体辅助抑制因子（抗原）