\n
\xa0
\xa0品系名称:BALB/cJGpt-Foxn1nu/Gpt
品系名称:品系名称:品系名称:品系名称:品系名称:BALB/cJGpt-Foxn1nu/GptBALB/cJGpt-Foxn1nu/GptBALB/cJGpt-BALB/cJGpt-Foxn1Foxn1Foxn1nununu/Gpt/Gpt品系类型: 自发突变品系编号:D000521
品系类型: 自发突变品系编号:品系类型: 自发突变品系编号:D000521D000521\xa0
\xa0\xa0
\xa0Foxn1(forkhead box N1)基因又称Hfh11、Fkh19,Foxn1蛋白是在胸腺上皮细胞中表达的蛋白质,是一种转录因子,参与免疫系统调节、代谢,在癌症和衰老中发挥重要的作用[1]。在人类中,该基因突变与T细胞免疫缺陷,皮肤疾病,先天性脱发和指甲营养不良相关[2-4]。Foxn1基因突变纯合小鼠(Foxn1nu)表现出毛发生长异常和胸腺上皮发育缺陷,小鼠出现无毛表型,与同窝有毛小鼠相比,毛囊数量及功能无差异,均能产生毛根和毛杆,但大多数毛杆不能正常穿透表皮,扭曲盘绕在膨胀的毛囊漏斗内。突变纯合小鼠的胸腺发育不良, \xa0 T细胞减少,缺乏细胞免疫功能。因此Foxn1基因突变纯合子小鼠又称为“裸鼠”。目前, 裸鼠模型已经广泛用于肿瘤学,免疫学,皮肤病学和移植的研究中。
Foxn1Foxn1((forkhead box N1forkhead box N1)基因又称)基因又称基因又称Hfh11Hfh11、、Fkh19Fkh19,,Foxn1Foxn1蛋白是在胸腺上皮细胞中表达的蛋白质,是一种转录因子,参与免疫系统调节、代谢,在癌症和衰老中发挥重要的作用蛋白是在胸腺上皮细胞中表达的蛋白质,是一种转录因子,参与免疫系统调节、代谢,在癌症和衰老中发挥重要的作用达的蛋白质,是一种转录因子,参与免疫系统调节、代谢,在癌症和衰老中发挥重要的作用[1][1][1][1][1]。在人类中,该基因突变与。在人类中,该基因突变与。在人类中,该基因突变与TT细胞免疫缺陷,皮肤疾病,先天性脱发和指甲营养不良相关细胞免疫缺陷,皮肤疾病,先天性脱发和指甲营养不良相关细胞免疫缺陷,皮肤疾病,先天性脱发和指甲营养不良相关[2-4][2-4][2-4][2-4][2-4]。。。Foxn1Foxn1基因突变纯合小鼠(基因突变纯合小鼠基因突变纯合小鼠(Foxn1nuFoxn1nu)表现出毛发生长异常和胸腺上皮发育缺陷,小鼠出现无毛表型,与同窝有毛小鼠相比,毛囊数量及功能无差异,均能产生毛根和毛杆,但大多数毛杆不能正常穿透表皮,扭曲盘绕在膨胀的毛囊漏斗内。突变纯合小鼠的胸腺发育不良, \xa0 )表现出毛发生长异常和胸腺上皮发育缺陷,小鼠表现出毛发生长异常和胸腺上皮发育缺陷,小鼠出现无毛表型,与同窝有毛小鼠相比,毛囊数量及功能无差异,均能产生毛根和毛杆,但大出现无毛表型,与同窝有毛小鼠相比,毛囊数量及功能无差异,均能产生毛根和毛杆,但大多数毛杆不能正常穿透表皮,扭曲盘绕在膨胀的毛囊漏斗内。突变纯合小鼠的胸腺发育不良, \xa0 多数毛杆不能正常穿透表皮,扭曲盘绕在膨胀的毛囊漏斗内。突变纯合小鼠的胸腺发育不良, \xa0 TTT细胞减少,缺乏细胞免疫功能。因此细胞减少,缺乏细胞免疫功能。因此细胞减少,缺乏细胞免疫功能。因此Foxn1Foxn1基因突变纯合子小鼠又称为“裸鼠”。目前, 裸鼠模型已经广泛用于肿瘤学,免疫学,皮肤病学和移植的研究中。基因突变纯合子小鼠又称为“裸鼠”。目前, 裸鼠模型已经广泛用于肿瘤学,免疫学,皮肤病学和移植的研究中。此品系小鼠可以应用于很多方面的支持性研究,包括:Foxn1nu相关的
此品系小鼠可以应用于很多方面的支持性研究,包括:此品系小鼠可以应用于很多方面的支持性研究,包括:此品系小鼠可以应用于很多方面的支持性研究,包括:此品系小鼠可以应用于很多方面的支持性研究,包括:此品系小鼠可以应用于很多方面的支持性研究,包括:Foxn1nuFoxn1nuFoxn1Foxn1Foxn1nununu相关的相关的相关的相关的相关的\xa0
\xa01、皮肤病学研究:皮毛结构缺陷;
11、皮肤病学研究:皮毛结构缺陷;、皮肤病学研究:皮毛结构缺陷;2、内分泌缺陷研究:肾上腺皮质缺陷,皮肤缺陷,甲状腺缺陷;
22、内分泌缺陷研究:肾上腺皮质缺陷,皮肤缺陷,甲状腺缺陷;、内分泌缺陷研究:肾上腺皮质缺陷,皮肤缺陷,甲状腺缺陷;3、免疫和炎症研究:免疫缺陷(T细胞缺乏);
33、免疫和炎症研究:免疫缺陷(、免疫和炎症研究:免疫缺陷(TT细胞缺乏);细胞缺乏);4、内部/器官研究:胸腺缺陷;
44、内部、内部//器官研究:胸腺缺陷;器官研究:胸腺缺陷;5、研究工具:癌症研究(异种移植/移植主体),免疫和炎症研究(T细胞缺乏)。
55、研究工具:癌症研究(异种移植、研究工具:癌症研究(异种移植//移植主体),免疫和炎症研究(移植主体),免疫和炎症研究(TT细胞缺乏)。细胞缺乏)。\xa0
\xa0饲料:普通饲料(6
脂肪含量)
鉴定方式:纯合子表型无毛,无需鉴定
\t配繁方式:纯合雄配杂合雌
\t配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。
\t产仔代乳情况:产仔好杂合雌鼠代乳好
\t描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增加,到5-6周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)在长到4.3w时会出现长毛(长毛高峰期),5.4w开始脱毛,6w已经脱毛干净,7.4w时♂开始反长毛这时的小鼠毛不易脱落。
\t饲料:普通饲料(6
脂肪含量)
饲料:普通饲料(6
脂肪含量)
鉴定方式:纯合子表型无毛,无需鉴定
\t鉴定方式:纯合子表型无毛,无需鉴定
鉴定方式:纯合子表型无毛,无需鉴定鉴定方式:纯合子表型无毛,无需鉴定鉴定方式:纯合子表型无毛,无需鉴定鉴定方式:纯合子表型无毛,无需鉴定鉴定方式:纯合子表型无毛,无需鉴定\t\t配繁方式:纯合雄配杂合雌
\t配繁方式:纯合雄配杂合雌
配繁方式:纯合雄配杂合雌配繁方式:纯合雄配杂合雌配繁方式:纯合雄配杂合雌配繁方式:纯合雄配杂合雌配繁方式:纯合雄配杂合雌\t\t配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。
\t配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。
配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 配繁注意:配繁雄鼠为纯合子,需进行小鼠外观挑选,预留配繁库存需筛选肉眼观察光 滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。滑不长毛小鼠保留;配繁雌鼠为杂合子,纯合子排卵异常且不代乳(可孕)。\t\t产仔代乳情况:产仔好杂合雌鼠代乳好
\t产仔代乳情况:产仔好杂合雌鼠代乳好
产仔代乳情况:产仔好杂合雌鼠代乳好产仔代乳情况:产仔好杂合雌鼠代乳好产仔代乳情况:产仔好杂合雌鼠代乳好产仔代乳情况:产仔好杂合雌鼠代乳好产仔代乳情况:产仔好杂合雌鼠代乳好\t\t描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增加,到5-6周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)在长到4.3w时会出现长毛(长毛高峰期),5.4w开始脱毛,6w已经脱毛干净,7.4w时♂开始反长毛这时的小鼠毛不易脱落。
\t描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增加,到5-6周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)在长到4.3w时会出现长毛(长毛高峰期),5.4w开始脱毛,6w已经脱毛干净,7.4w时♂开始反长毛这时的小鼠毛不易脱落。
描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增加,到描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增加,到描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0描述:皮肤眼观上为光裸的,并由此引起了人们的误解:“裸鼠”就是“体表无毛的”。 \xa0实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增实际上,裸鼠出生后大约十天左右,在头面部、颈部可见稀疏的毛发生长;随着周龄增加,到加,到加,到加,到5-65-65-65-65-6周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)在长到周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)在长到周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是周,在躯干的其他部位也可见稀疏毛发的生长。这些穿透了表皮的毛杆也是严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)严重扭曲的,而且经常在长到应有长度前就折断了,因此大家看到的都是稀疏、较短的被毛。根据繁育经验:小鼠(♂♀)在长到在长到在长到在长到4.3w4.3w4.3w4.3w4.3w时会出现长毛(长毛高峰期),时会出现长毛(长毛高峰期),时会出现长毛时会出现长毛时会出现长毛时会出现长毛(长毛高峰期),(长毛高峰期),(长毛高峰期),5.4w5.4w5.4w5.4w5.4w开始脱毛,开始脱毛,开始脱毛,开始脱毛,开始脱毛,6w6w6w6w6w已经脱毛干净,已经脱毛干净,已经脱毛干净,已经脱毛干净,已经脱毛干净,已经脱毛干净,7.4w7.4w7.4w7.4w7.4w时♂开始反长毛这时的小鼠毛不易脱落。时♂开始反长毛这时的小鼠毛不易脱落。时♂开始反长毛这时的小鼠毛不易脱落。时♂开始反长毛这时的小鼠毛不易脱落。时♂开始反长毛这时的小鼠毛不易脱落。时♂开始反长毛这时的小鼠毛不易脱落。\t\xa0
\xa0


血常规
血常规血常规血常规血常规血常规血常规Hematol
HematolHematolHematolHematolHematolHematol| \t\t\t Parameter \t\t\t | \t\t\t\t\t\t Units \t\t\t | \t\t\t\t\t\t 16W(♂) \t\t\t | \t\t\t\t\t\t 16W(♀) \t\t\t | \t\t
| \t\t\t WBC \t\t\t | \t\t\t\t\t\t 103cells/mm3 \t\t\t | \t\t\t\t\t\t 2.90±0.51 \t\t\t | \t\t\t\t\t\t 1.98±0.91 \t\t\t | \t\t
| \t\t\t RBC \t\t\t | \t\t\t\t\t\t 106cells/mm3 \t\t\t | \t\t\t\t\t\t 10.03±0.56 \t\t\t | \t\t\t\t\t\t 9.83±0.53 \t\t\t | \t\t
| \t\t\t HB \t\t\t | \t\t\t\t\t\t g/L \t\t\t | \t\t\t\t\t\t 154.55±4.75 \t\t\t | \t\t\t\t\t\t 158.71±5.95 \t\t\t | \t\t
| \t\t\t HCT \t\t\t | \t\t\t\t\t\t % \t\t\t | \t\t\t\t\t\t 55.30±2.14 \t\t\t | \t\t\t\t\t\t 56.18±2.67 \t\t\t | \t\t
| \t\t\t MCV \t\t\t | \t\t\t\t\t\t fL \t\t\t | \t\t\t\t\t\t 55.22±2.55 \t\t\t | \t\t\t\t\t\t 57.18±1.85 \t\t\t | \t\t
| \t\t\t MCH \t\t\t | \t\t\t\t\t\t Pg \t\t\t | \t\t\t\t\t\t 15.45±0.93 \t\t\t | \t\t\t\t\t\t 16.17±0.54 \t\t\t | \t\t
| \t\t\t MCHC \t\t\t | \t\t\t\t\t\t g/L \t\t\t | \t\t\t\t\t\t 279.91±8.96 \t\t\t | \t\t\t\t\t\t 282.76±6.78 \t\t\t | \t\t
| \t\t\t RDW \t\t\t | \t\t\t\t\t\t % \t\t\t | \t\t\t\t\t\t 16.68±0.79 \t\t\t | \t\t\t\t\t\t 16.77±1.04 \t\t\t | \t\t
| \t\t\t PLT \t\t\t | \t\t\t\t\t\t 103cells/mm3 \t\t\t | \t\t\t\t\t\t 868.55±101.64 \t\t\t | \t\t\t\t\t\t 790.24±168.98 \t\t\t | \t\t
| \t\t\t MPV \t\t\t | \t\t\t\t\t\t fL \t\t\t | \t\t\t\t\t\t 4.32±0.22 \t\t\t | \t\t\t\t\t\t 4.24±0.45 \t\t\t | \t\t
| \t\t\t NE# \t\t\t | \t\t\t\t\t\t 103cells/mm3 \t\t\t | \t\t\t\t\t\t 1.10±0.23 \t\t\t | \t\t\t\t\t\t 0.49±0.19 \t\t\t | \t\t
| \t\t\t NE% \t\t\t | \t\t\t\t\t\t % \t\t\t | \t\t\t\t\t\t 36.17±6.23 \t\t\t | \t\t\t\t\t\t 25.60±7.61 \t\t\t | \t\t
| \t\t\t LY# \t\t\t | \t\t\t\t\t\t 103cells/mm3 \t\t\t | \t\t\t\t\t\t 1.52±0.35 \t\t\t | \t\t\t\t\t\t 1.19±0.69 \t\t\t | \t\t
| \t\t\t LY% \t\t\t | \t\t\t\t\t\t % \t\t\t | \t\t\t\t\t\t 52.73±7.41 \t\t\t | \t\t\t\t\t\t 58.65±9.20 \t\t\t | \t\t
| \t\t\t EO# \t\t\t | \t\t\t\t\t\t 103cells/mm3 \t\t\t | \t\t\t\t\t\t 0.01±0.01 \t\t\t | \t\t\t\t\t\t 0.00±0.01 \t\t\t | \t\t
| \t\t\t EO% \t\t\t | \t\t\t\t\t\t % \t\t\t | \t\t\t\t\t\t 0.26±0.24 \t\t\t | \t\t\t\t\t\t 0.28±0.18 \t\t\t | \t\t
| \t\t\t MO# \t\t\t | \t\t\t\t\t\t 103cells/mm3 \t\t\t | \t\t\t\t\t\t 0.27±0.06 \t\t\t | \t\t\t\t\t\t 0.30±0.16 \t\t\t | \t\t
| \t\t\t MO% \t\t\t | \t\t\t\t\t\t % \t\t\t | \t\t\t\t\t\t 10.80±3.86 \t\t\t | \t\t\t\t\t\t 15.40±4.48 \t\t\t | \t\t
| \t\t\t BA# \t\t\t | \t\t\t\t\t\t 103cells/mm3 \t\t\t | \t\t\t\t\t\t 0.00±0.00 \t\t\t | \t\t\t\t\t\t 0.00±0.00 \t\t\t | \t\t
| \t\t\t BA% \t\t\t | \t\t\t\t\t\t % \t\t\t | \t\t\t\t\t\t 0.05±0.06 \t\t\t | \t\t\t\t\t\t 0.07±0.13 \t\t\t | \t\t
Parameter
\t\t\tUnits
\t\t\t16W(♂)
\t\t\t16W(♀)
\t\t\tWBC
\t\t\t103cells/mm3
\t\t\t2.90±0.51
\t\t\t1.98±0.91
\t\t\tRBC
\t\t\t106cells/mm3
\t\t\t10.03±0.56
\t\t\t9.83±0.53
\t\t\tHB
\t\t\tg/L
\t\t\t154.55±4.75
\t\t\t158.71±5.95
\t\t\tHCT
\t\t\t%
\t\t\t55.30±2.14
\t\t\t56.18±2.67
\t\t\tMCV
\t\t\tfL
\t\t\t55.22±2.55
\t\t\t57.18±1.85
\t\t\tMCH
\t\t\tPg
\t\t\t15.45±0.93
\t\t\t16.17±0.54
\t\t\tMCHC
\t\t\tg/L
\t\t\t279.91±8.96
\t\t\t282.76±6.78
\t\t\tRDW
\t\t\t%
\t\t\t16.68±0.79
\t\t\t16.77±1.04
\t\t\tPLT
\t\t\t103cells/mm3
\t\t\t868.55±101.64
\t\t\t790.24±168.98
\t\t\tMPV
\t\t\tfL
\t\t\t4.32±0.22
\t\t\t4.24±0.45
\t\t\tNE#
\t\t\t103cells/mm3
\t\t\t1.10±0.23
\t\t\t0.49±0.19
\t\t\tNE%
\t\t\t%
\t\t\t36.17±6.23
\t\t\t25.60±7.61
\t\t\tLY#
\t\t\t103cells/mm3
\t\t\t1.52±0.35
\t\t\t1.19±0.69
\t\t\tLY%
\t\t\t%
\t\t\t52.73±7.41
\t\t\t58.65±9.20
\t\t\tEO#
\t\t\t103cells/mm3
\t\t\t0.01±0.01
\t\t\t0.00±0.01
\t\t\tEO%
\t\t\t%
\t\t\t0.26±0.24
\t\t\t0.28±0.18
\t\t\tMO#
\t\t\t103cells/mm3
\t\t\t0.27±0.06
\t\t\t0.30±0.16
\t\t\tMO%
\t\t\t%
\t\t\t10.80±3.86
\t\t\t15.40±4.48
\t\t\tBA#
\t\t\t103cells/mm3
\t\t\t0.00±0.00
\t\t\t0.00±0.00
\t\t\tBA%
\t\t\t%
\t\t\t0.05±0.06
\t\t\t0.07±0.13
\t\t\tParameter
\t\t\tUnits
\t\t\t16W(♂)
\t\t\t16W(♀)
\t\t\tParameter
\t\t\tParameter
ParameterParameterParameterParameter\t\t\t\t\t\tUnits
\t\t\tUnits
UnitsUnitsUnitsUnits\t\t\t\t\t\t16W(♂)
\t\t\t16W(♂)
16W(♂)16W(♂)16W(♂)16W(♂)\t\t\t\t\t\t16W(♀)
\t\t\t16W(♀)
16W(♀)16W(♀)16W(♀)16W(♀)\t\t\t\t\t\t\tWBC
\t\t\t103cells/mm3
\t\t\t2.90±0.51
\t\t\t1.98±0.91
\t\t\tWBC
\t\t\tWBC
WBCWBCWBCWBC\t\t\t\t\t\t103cells/mm3
\t\t\t103cells/mm3
103cells/mm3103cells/mm31010333cells/mm3cells/mm3\t\t\t\t\t\t2.90±0.51
\t\t\t2.90±0.51
2.90±0.512.90±0.512.90±0.512.90±0.51\t\t\t\t\t\t1.98±0.91
\t\t\t1.98±0.91
1.98±0.911.98±0.911.98±0.911.98±0.91\t\t\t\t\t\t\tRBC
\t\t\t106cells/mm3
\t\t\t10.03±0.56
\t\t\t9.83±0.53
\t\t\tRBC
\t\t\tRBC
RBCRBCRBCRBC\t\t\t\t\t\t106cells/mm3
\t\t\t106cells/mm3
106cells/mm3106cells/mm31010666cells/mm3cells/mm3\t\t\t\t\t\t10.03±0.56
\t\t\t10.03±0.56
10.03±0.5610.03±0.5610.03±0.5610.03±0.56\t\t\t\t\t\t9.83±0.53
\t\t\t9.83±0.53
9.83±0.539.83±0.539.83±0.539.83±0.53\t\t\t\t\t\t\tHB
\t\t\tg/L
\t\t\t154.55±4.75
\t\t\t158.71±5.95
\t\t\tHB
\t\t\tHB
HBHBHBHB\t\t\t\t\t\tg/L
\t\t\tg/L
g/Lg/Lg/Lg/L\t\t\t\t\t\t154.55±4.75
\t\t\t154.55±4.75
154.55±4.75154.55±4.75154.55±4.75154.55±4.75\t\t\t\t\t\t158.71±5.95
\t\t\t158.71±5.95
158.71±5.95158.71±5.95158.71±5.95158.71±5.95\t\t\t\t\t\t\tHCT
\t\t\t%
\t\t\t55.30±2.14
\t\t\t56.18±2.67
\t\t\tHCT
\t\t\tHCT
HCTHCTHCTHCT\t\t\t\t\t\t%
\t\t\t%
%%%%\t\t\t\t\t\t55.30±2.14
\t\t\t55.30±2.14
55.30±2.1455.30±2.1455.30±2.1455.30±2.14\t\t\t\t\t\t56.18±2.67
\t\t\t56.18±2.67
56.18±2.6756.18±2.6756.18±2.6756.18±2.67\t\t\t\t\t\t\tMCV
\t\t\tfL
\t\t\t55.22±2.55
\t\t\t57.18±1.85
\t\t\tMCV
\t\t\tMCV
MCVMCVMCVMCV\t\t\t\t\t\tfL
\t\t\tfL
fLfLfLfL\t\t\t\t\t\t55.22±2.55
\t\t\t55.22±2.55
55.22±2.5555.22±2.5555.22±2.5555.22±2.55\t\t\t\t\t\t57.18±1.85
\t\t\t57.18±1.85
57.18±1.8557.18±1.8557.18±1.8557.18±1.85\t\t\t\t\t\t\tMCH
\t\t\tPg
\t\t\t15.45±0.93
\t\t\t16.17±0.54
\t\t\tMCH
\t\t\tMCH
MCHMCHMCHMCH\t\t\t\t\t\tPg
\t\t\tPg
PgPgPgPg\t\t\t\t\t\t15.45±0.93
\t\t\t15.45±0.93
15.45±0.9315.45±0.9315.45±0.9315.45±0.93\t\t\t\t\t\t16.17±0.54
\t\t\t16.17±0.54
16.17±0.5416.17±0.5416.17±0.5416.17±0.54\t\t\t\t\t\t\tMCHC
\t\t\tg/L
\t\t\t279.91±8.96
\t\t\t282.76±6.78
\t\t\tMCHC
\t\t\tMCHC
MCHCMCHCMCHCMCHC\t\t\t\t\t\tg/L
\t\t\tg/L
g/Lg/Lg/Lg/L\t\t\t\t\t\t279.91±8.96
\t\t\t279.91±8.96
279.91±8.96279.91±8.96279.91±8.96279.91±8.96\t\t\t\t\t\t282.76±6.78
\t\t\t282.76±6.78
282.76±6.78282.76±6.78282.76±6.78282.76±6.78\t\t\t\t\t\t\tRDW
\t\t\t%
\t\t\t16.68±0.79
\t\t\t16.77±1.04
\t\t\tRDW
\t\t\tRDW
RDWRDWRDWRDW\t\t\t\t\t\t%
\t\t\t%
%%%%\t\t\t\t\t\t16.68±0.79
\t\t\t16.68±0.79
16.68±0.7916.68±0.7916.68±0.7916.68±0.79\t\t\t\t\t\t16.77±1.04
\t\t\t16.77±1.04
16.77±1.0416.77±1.0416.77±1.0416.77±1.04\t\t\t\t\t\t\tPLT
\t\t\t103cells/mm3
\t\t\t868.55±101.64
\t\t\t790.24±168.98
\t\t\tPLT
\t\t\tPLT
PLTPLTPLTPLT\t\t\t\t\t\t103cells/mm3
\t\t\t103cells/mm3
103cells/mm3103cells/mm31010333cells/mm3cells/mm3\t\t\t\t\t\t868.55±101.64
\t\t\t868.55±101.64
868.55±101.64868.55±101.64868.55±101.64868.55±101.64\t\t\t\t\t\t790.24±168.98
\t\t\t790.24±168.98
790.24±168.98790.24±168.98790.24±168.98790.24±168.98\t\t\t\t\t\t\tMPV
\t\t\tfL
\t\t\t4.32±0.22
\t\t\t4.24±0.45
\t\t\tMPV
\t\t\tMPV
MPVMPVMPVMPV\t\t\t\t\t\tfL
\t\t\tfL
fLfLfLfL\t\t\t\t\t\t4.32±0.22
\t\t\t4.32±0.22
4.32±0.224.32±0.224.32±0.224.32±0.22\t\t\t\t\t\t4.24±0.45
\t\t\t4.24±0.45
4.24±0.454.24±0.454.24±0.454.24±0.45\t\t\t\t\t\t\tNE#
\t\t\t103cells/mm3
\t\t\t1.10±0.23
\t\t\t0.49±0.19
\t\t\tNE#
\t\t\tNE#
NE#NE#NE#NE#\t\t\t\t\t\t103cells/mm3
\t\t\t103cells/mm3
103cells/mm3103cells/mm31010333cells/mm3cells/mm3\t\t\t\t\t\t1.10±0.23
\t\t\t1.10±0.23
1.10±0.231.10±0.231.10±0.231.10±0.23\t\t\t\t\t\t0.49±0.19
\t\t\t0.49±0.19
0.49±0.190.49±0.190.49±0.190.49±0.19\t\t\t\t\t\t\tNE%
\t\t\t%
\t\t\t36.17±6.23
\t\t\t25.60±7.61
\t\t\tNE%
\t\t\tNE%
NE%NE%NE%NE%\t\t\t\t\t\t%
\t\t\t%
%%%%\t\t\t\t\t\t36.17±6.23
\t\t\t36.17±6.23
36.17±6.2336.17±6.2336.17±6.2336.17±6.23\t\t\t\t\t\t25.60±7.61
\t\t\t25.60±7.61
25.60±7.6125.60±7.6125.60±7.6125.60±7.61\t\t\t\t\t\t\tLY#
\t\t\t103cells/mm3
\t\t\t1.52±0.35
\t\t\t1.19±0.69
\t\t\tLY#
\t\t\tLY#
LY#LY#LY#LY#\t\t\t\t\t\t103cells/mm3
\t\t\t103cells/mm3
103cells/mm3103cells/mm31010333cells/mm3cells/mm3\t\t\t\t\t\t1.52±0.35
\t\t\t1.52±0.35
1.52±0.351.52±0.351.52±0.351.52±0.35\t\t\t\t\t\t1.19±0.69
\t\t\t1.19±0.69
1.19±0.691.19±0.691.19±0.691.19±0.69\t\t\t\t\t\t\tLY%
\t\t\t%
\t\t\t52.73±7.41
\t\t\t58.65±9.20
\t\t\tLY%
\t\t\tLY%
LY%LY%LY%LY%\t\t\t\t\t\t%
\t\t\t%
%%%%\t\t\t\t\t\t52.73±7.41
\t\t\t52.73±7.41
52.73±7.4152.73±7.4152.73±7.4152.73±7.41\t\t\t\t\t\t58.65±9.20
\t\t\t58.65±9.20
58.65±9.2058.65±9.2058.65±9.2058.65±9.20\t\t\t\t\t\t\tEO#
\t\t\t103cells/mm3
\t\t\t0.01±0.01
\t\t\t0.00±0.01
\t\t\tEO#
\t\t\tEO#
EO#EO#EO#EO#\t\t\t\t\t\t103cells/mm3
\t\t\t103cells/mm3
103cells/mm3103cells/mm31010333cells/mm3cells/mm3\t\t\t\t\t\t0.01±0.01
\t\t\t0.01±0.01
0.01±0.010.01±0.010.01±0.010.01±0.01\t\t\t\t\t\t0.00±0.01
\t\t\t0.00±0.01
0.00±0.010.00±0.010.00±0.010.00±0.01\t\t\t\t\t\t\tEO%
\t\t\t%
\t\t\t0.26±0.24
\t\t\t0.28±0.18
\t\t\tEO%
\t\t\tEO%
EO%EO%EO%EO%\t\t\t\t\t\t%
\t\t\t%
%%%%\t\t\t\t\t\t0.26±0.24
\t\t\t0.26±0.24
0.26±0.240.26±0.240.26±0.240.26±0.24\t\t\t\t\t\t0.28±0.18
\t\t\t0.28±0.18
0.28±0.180.28±0.180.28±0.180.28±0.18\t\t\t\t\t\t\tMO#
\t\t\t103cells/mm3
\t\t\t0.27±0.06
\t\t\t0.30±0.16
\t\t\tMO#
\t\t\tMO#
MO#MO#MO#MO#\t\t\t\t\t\t103cells/mm3
\t\t\t103cells/mm3
103cells/mm3103cells/mm31010333cells/mm3cells/mm3\t\t\t\t\t\t0.27±0.06
\t\t\t0.27±0.06
0.27±0.060.27±0.060.27±0.060.27±0.06\t\t\t\t\t\t0.30±0.16
\t\t\t0.30±0.16
0.30±0.160.30±0.160.30±0.160.30±0.16\t\t\t\t\t\t\tMO%
\t\t\t%
\t\t\t10.80±3.86
\t\t\t15.40±4.48
\t\t\tMO%
\t\t\tMO%
MO%MO%MO%MO%\t\t\t\t\t\t%
\t\t\t%
%%%%\t\t\t\t\t\t10.80±3.86
\t\t\t10.80±3.86
10.80±3.8610.80±3.8610.80±3.8610.80±3.86\t\t\t\t\t\t15.40±4.48
\t\t\t15.40±4.48
15.40±4.4815.40±4.4815.40±4.4815.40±4.48\t\t\t\t\t\t\tBA#
\t\t\t103cells/mm3
\t\t\t0.00±0.00
\t\t\t0.00±0.00
\t\t\tBA#
\t\t\tBA#
BA#BA#BA#BA#\t\t\t\t\t\t103cells/mm3
\t\t\t103cells/mm3
103cells/mm3103cells/mm31010333cells/mm3cells/mm3\t\t\t\t\t\t0.00±0.00
\t\t\t0.00±0.00
0.00±0.000.00±0.000.00±0.000.00±0.00\t\t\t\t\t\t0.00±0.00
\t\t\t0.00±0.00
0.00±0.000.00±0.000.00±0.000.00±0.00\t\t\t\t\t\t\tBA%
\t\t\t%
\t\t\t0.05±0.06
\t\t\t0.07±0.13
\t\t\tBA%
\t\t\tBA%
BA%BA%BA%BA%\t\t\t\t\t\t%
\t\t\t%
%%%%\t\t\t\t\t\t0.05±0.06
\t\t\t0.05±0.06
0.05±0.060.05±0.060.05±0.060.05±0.06\t\t\t\t\t\t0.07±0.13
\t\t\t0.07±0.13
0.07±0.130.07±0.130.07±0.130.07±0.13\t\t\t\t\t\t\xa0
\xa0\xa0
\xa0| \t\t\t Biochemistry \t\t\t | \t\t|||
| \t\t\t Parameter \t\t\t | \t\t\t\t\t\t Units \t\t\t | \t\t\t\t\t\t 16W(♂) \t\t\t | \t\t\t\t\t\t 16W(♀) \t\t\t | \t\t
| \t\t\t ALT \t\t\t | \t\t\t\t\t\t IU/L \t\t\t | \t\t\t\t\t\t 38.22±18.39 \t\t\t | \t\t\t\t\t\t 34.39±12.17 \t\t\t | \t\t
| \t\t\t AST \t\t\t | \t\t\t\t\t\t IU/L \t\t\t | \t\t\t\t\t\t 77.39±41.29 \t\t\t | \t\t\t\t\t\t 88.57±43.22 \t\t\t | \t\t
| \t\t\t AKP \t\t\t | \t\t\t\t\t\t IU/L \t\t\t | \t\t\t\t\t\t 90.57±15.23 \t\t\t | \t\t\t\t\t\t 102.48±24.95 \t\t\t | \t\t
| \t\t\t TP \t\t\t | \t\t\t\t\t\t g/L \t\t\t | \t\t\t\t\t\t 51.62±3.02 \t\t\t | \t\t\t\t\t\t 52.09±2.33 \t\t\t | \t\t
| \t\t\t ALB \t\t\t | \t\t\t\t\t\t g/L \t\t\t | \t\t\t\t\t\t 33.16±2.34 \t\t\t | \t\t\t\t\t\t 36.84±2.19 \t\t\t | \t\t
| \t\t\t TBIL \t\t\t | \t\t\t\t\t\t μmol/L \t\t\t | \t\t\t\t\t\t 1.14±0.40 \t\t\t | \t\t\t\t\t\t 0.9±0.21 \t\t\t | \t\t
| \t\t\t GLU \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t 9.49±1.29 \t\t\t | \t\t\t\t\t\t 7.28±1.55 \t\t\t | \t\t
| \t\t\t BUN \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t 7.47±1.64 \t\t\t | \t\t\t\t\t\t 6.96±1.48 \t\t\t | \t\t
| \t\t\t CREA \t\t\t | \t\t\t\t\t\t μmol/L \t\t\t | \t\t\t\t\t\t 13.51±2.59 \t\t\t | \t\t\t\t\t\t 13.29±1.76 \t\t\t | \t\t
| \t\t\t Ca \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t 2.6±0.15 \t\t\t | \t\t\t\t\t\t 2.6±0.09 \t\t\t | \t\t
| \t\t\t P \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t 2.34±0.69 \t\t\t | \t\t\t\t\t\t 2.75±0.54 \t\t\t | \t\t
| \t\t\t Fe \t\t\t | \t\t\t\t\t\t μmol/L \t\t\t | \t\t\t\t\t\t 42.57±5.25 \t\t\t | \t\t\t\t\t\t 35.98±8.05 \t\t\t | \t\t
Biochemistry
\t\t\tParameter
\t\t\tUnits
\t\t\t16W(♂)
\t\t\t16W(♀)
\t\t\tALT
\t\t\tIU/L
\t\t\t38.22±18.39
\t\t\t34.39±12.17
\t\t\tAST
\t\t\tIU/L
\t\t\t77.39±41.29
\t\t\t88.57±43.22
\t\t\tAKP
\t\t\tIU/L
\t\t\t90.57±15.23
\t\t\t102.48±24.95
\t\t\tTP
\t\t\tg/L
\t\t\t51.62±3.02
\t\t\t52.09±2.33
\t\t\tALB
\t\t\tg/L
\t\t\t33.16±2.34
\t\t\t36.84±2.19
\t\t\tTBIL
\t\t\tμmol/L
\t\t\t1.14±0.40
\t\t\t0.9±0.21
\t\t\tGLU
\t\t\tmmol/L
\t\t\t9.49±1.29
\t\t\t7.28±1.55
\t\t\tBUN
\t\t\tmmol/L
\t\t\t7.47±1.64
\t\t\t6.96±1.48
\t\t\tCREA
\t\t\tμmol/L
\t\t\t13.51±2.59
\t\t\t13.29±1.76
\t\t\tCa
\t\t\tmmol/L
\t\t\t2.6±0.15
\t\t\t2.6±0.09
\t\t\tP
\t\t\tmmol/L
\t\t\t2.34±0.69
\t\t\t2.75±0.54
\t\t\tFe
\t\t\tμmol/L
\t\t\t42.57±5.25
\t\t\t35.98±8.05
\t\t\tBiochemistry
\t\t\tBiochemistry
\t\t\tBiochemistry
BiochemistryBiochemistryBiochemistryBiochemistryBiochemistryBiochemistry\t\t\t\t\t\t\tParameter
\t\t\tUnits
\t\t\t16W(♂)
\t\t\t16W(♀)
\t\t\tParameter
\t\t\tParameter
ParameterParameterParameterParameter\t\t\t\t\t\tUnits
\t\t\tUnits
UnitsUnitsUnitsUnits\t\t\t\t\t\t16W(♂)
\t\t\t16W(♂)
16W(♂)16W(♂)16W(♂)16W(♂)\t\t\t\t\t\t16W(♀)
\t\t\t16W(♀)
16W(♀)16W(♀)16W(♀)16W(♀)\t\t\t\t\t\t\tALT
\t\t\tIU/L
\t\t\t38.22±18.39
\t\t\t34.39±12.17
\t\t\tALT
\t\t\tALT
ALTALTALTALT\t\t\t\t\t\tIU/L
\t\t\tIU/L
IU/LIU/LIU/LIU/L\t\t\t\t\t\t38.22±18.39
\t\t\t38.22±18.39
38.22±18.3938.22±18.3938.22±18.3938.22±18.39\t\t\t\t\t\t34.39±12.17
\t\t\t34.39±12.17
34.39±12.1734.39±12.1734.39±12.1734.39±12.17\t\t\t\t\t\t\tAST
\t\t\tIU/L
\t\t\t77.39±41.29
\t\t\t88.57±43.22
\t\t\tAST
\t\t\tAST
ASTASTASTAST\t\t\t\t\t\tIU/L
\t\t\tIU/L
IU/LIU/LIU/LIU/L\t\t\t\t\t\t77.39±41.29
\t\t\t77.39±41.29
77.39±41.2977.39±41.2977.39±41.2977.39±41.29\t\t\t\t\t\t88.57±43.22
\t\t\t88.57±43.22
88.57±43.2288.57±43.2288.57±43.2288.57±43.22\t\t\t\t\t\t\tAKP
\t\t\tIU/L
\t\t\t90.57±15.23
\t\t\t102.48±24.95
\t\t\tAKP
\t\t\tAKP
AKPAKPAKPAKP\t\t\t\t\t\tIU/L
\t\t\tIU/L
IU/LIU/LIU/LIU/L\t\t\t\t\t\t90.57±15.23
\t\t\t90.57±15.23
90.57±15.2390.57±15.2390.57±15.2390.57±15.23\t\t\t\t\t\t102.48±24.95
\t\t\t102.48±24.95
102.48±24.95102.48±24.95102.48±24.95102.48±24.95\t\t\t\t\t\t\tTP
\t\t\tg/L
\t\t\t51.62±3.02
\t\t\t52.09±2.33
\t\t\tTP
\t\t\tTP
TPTPTPTP\t\t\t\t\t\tg/L
\t\t\tg/L
g/Lg/Lg/Lg/L\t\t\t\t\t\t51.62±3.02
\t\t\t51.62±3.02
51.62±3.0251.62±3.0251.62±3.0251.62±3.02\t\t\t\t\t\t52.09±2.33
\t\t\t52.09±2.33
52.09±2.3352.09±2.3352.09±2.3352.09±2.33\t\t\t\t\t\t\tALB
\t\t\tg/L
\t\t\t33.16±2.34
\t\t\t36.84±2.19
\t\t\tALB
\t\t\tALB
ALBALBALBALB\t\t\t\t\t\tg/L
\t\t\tg/L
g/Lg/Lg/Lg/L\t\t\t\t\t\t33.16±2.34
\t\t\t33.16±2.34
33.16±2.3433.16±2.3433.16±2.3433.16±2.34\t\t\t\t\t\t36.84±2.19
\t\t\t36.84±2.19
36.84±2.1936.84±2.1936.84±2.1936.84±2.19\t\t\t\t\t\t\tTBIL
\t\t\tμmol/L
\t\t\t1.14±0.40
\t\t\t0.9±0.21
\t\t\tTBIL
\t\t\tTBIL
TBILTBILTBILTBIL\t\t\t\t\t\tμmol/L
\t\t\tμmol/L
μmol/Lμmol/Lμmol/Lμmol/L\t\t\t\t\t\t1.14±0.40
\t\t\t1.14±0.40
1.14±0.401.14±0.401.14±0.401.14±0.40\t\t\t\t\t\t0.9±0.21
\t\t\t0.9±0.21
0.9±0.210.9±0.210.9±0.210.9±0.21\t\t\t\t\t\t\tGLU
\t\t\tmmol/L
\t\t\t9.49±1.29
\t\t\t7.28±1.55
\t\t\tGLU
\t\t\tGLU
GLUGLUGLUGLU\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t9.49±1.29
\t\t\t9.49±1.29
9.49±1.299.49±1.299.49±1.299.49±1.29\t\t\t\t\t\t7.28±1.55
\t\t\t7.28±1.55
7.28±1.557.28±1.557.28±1.557.28±1.55\t\t\t\t\t\t\tBUN
\t\t\tmmol/L
\t\t\t7.47±1.64
\t\t\t6.96±1.48
\t\t\tBUN
\t\t\tBUN
BUNBUNBUNBUN\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t7.47±1.64
\t\t\t7.47±1.64
7.47±1.647.47±1.647.47±1.647.47±1.64\t\t\t\t\t\t6.96±1.48
\t\t\t6.96±1.48
6.96±1.486.96±1.486.96±1.486.96±1.48\t\t\t\t\t\t\tCREA
\t\t\tμmol/L
\t\t\t13.51±2.59
\t\t\t13.29±1.76
\t\t\tCREA
\t\t\tCREA
CREACREACREACREA\t\t\t\t\t\tμmol/L
\t\t\tμmol/L
μmol/Lμmol/Lμmol/Lμmol/L\t\t\t\t\t\t13.51±2.59
\t\t\t13.51±2.59
13.51±2.5913.51±2.5913.51±2.5913.51±2.59\t\t\t\t\t\t13.29±1.76
\t\t\t13.29±1.76
13.29±1.7613.29±1.7613.29±1.7613.29±1.76\t\t\t\t\t\t\tCa
\t\t\tmmol/L
\t\t\t2.6±0.15
\t\t\t2.6±0.09
\t\t\tCa
\t\t\tCa
CaCaCaCa\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t2.6±0.15
\t\t\t2.6±0.15
2.6±0.152.6±0.152.6±0.152.6±0.15\t\t\t\t\t\t2.6±0.09
\t\t\t2.6±0.09
2.6±0.092.6±0.092.6±0.092.6±0.09\t\t\t\t\t\t\tP
\t\t\tmmol/L
\t\t\t2.34±0.69
\t\t\t2.75±0.54
\t\t\tP
\t\t\tP
PPPP\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t2.34±0.69
\t\t\t2.34±0.69
2.34±0.692.34±0.692.34±0.692.34±0.69\t\t\t\t\t\t2.75±0.54
\t\t\t2.75±0.54
2.75±0.542.75±0.542.75±0.542.75±0.54\t\t\t\t\t\t\tFe
\t\t\tμmol/L
\t\t\t42.57±5.25
\t\t\t35.98±8.05
\t\t\tFe
\t\t\tFe
FeFeFeFe\t\t\t\t\t\tμmol/L
\t\t\tμmol/L
μmol/Lμmol/Lμmol/Lμmol/L\t\t\t\t\t\t42.57±5.25
\t\t\t42.57±5.25
42.57±5.2542.57±5.2542.57±5.2542.57±5.25\t\t\t\t\t\t35.98±8.05
\t\t\t35.98±8.05
35.98±8.0535.98±8.0535.98±8.0535.98±8.05\t\t\t\t\t\t\xa0
\xa0| \t\t\t CHOl \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t 3.26±0.27 \t\t\t | \t\t\t\t\t\t 2.8±0.32 \t\t\t | \t\t
| \t\t\t TG \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t 1.01±0.56 \t\t\t | \t\t\t\t\t\t 0.5±0.16 \t\t\t | \t\t
| \t\t\t HDL-C \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t 2.48±0.23 \t\t\t | \t\t\t\t\t\t 2.01±0.20 \t\t\t | \t\t
| \t\t\t LDL-C \t\t\t | \t\t\t\t\t\t mmol/L \t\t\t | \t\t\t\t\t\t / \t\t\t | \t\t\t\t\t\t / \t\t\t | \t\t
CHOl
\t\t\tmmol/L
\t\t\t3.26±0.27
\t\t\t2.8±0.32
\t\t\tTG
\t\t\tmmol/L
\t\t\t1.01±0.56
\t\t\t0.5±0.16
\t\t\tHDL-C
\t\t\tmmol/L
\t\t\t2.48±0.23
\t\t\t2.01±0.20
\t\t\tLDL-C
\t\t\tmmol/L
\t\t\t/
\t\t\t/
\t\t\tCHOl
\t\t\tmmol/L
\t\t\t3.26±0.27
\t\t\t2.8±0.32
\t\t\tCHOl
\t\t\tCHOl
CHOlCHOlCHOlCHOl\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t3.26±0.27
\t\t\t3.26±0.27
3.26±0.273.26±0.273.26±0.273.26±0.27\t\t\t\t\t\t2.8±0.32
\t\t\t2.8±0.32
2.8±0.322.8±0.322.8±0.322.8±0.32\t\t\t\t\t\t\tTG
\t\t\tmmol/L
\t\t\t1.01±0.56
\t\t\t0.5±0.16
\t\t\tTG
\t\t\tTG
TGTGTGTG\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t1.01±0.56
\t\t\t1.01±0.56
1.01±0.561.01±0.561.01±0.561.01±0.56\t\t\t\t\t\t0.5±0.16
\t\t\t0.5±0.16
0.5±0.160.5±0.160.5±0.160.5±0.16\t\t\t\t\t\t\tHDL-C
\t\t\tmmol/L
\t\t\t2.48±0.23
\t\t\t2.01±0.20
\t\t\tHDL-C
\t\t\tHDL-C
HDL-CHDL-CHDL-CHDL-C\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t2.48±0.23
\t\t\t2.48±0.23
2.48±0.232.48±0.232.48±0.232.48±0.23\t\t\t\t\t\t2.01±0.20
\t\t\t2.01±0.20
2.01±0.202.01±0.202.01±0.202.01±0.20\t\t\t\t\t\t\tLDL-C
\t\t\tmmol/L
\t\t\t/
\t\t\t/
\t\t\tLDL-C
\t\t\tLDL-C
LDL-CLDL-CLDL-CLDL-C\t\t\t\t\t\tmmol/L
\t\t\tmmol/L
mmol/Lmmol/Lmmol/Lmmol/L\t\t\t\t\t\t/
\t\t\t/
////\t\t\t\t\t\t/
\t\t\t/
////\t\t\t\t\t\t\xa0
\xa0流式细胞
流式细胞流式细胞流式细胞流式细胞流式细胞流式细胞\xa0
\xa0| \t\t\t Flow cytometr \t\t\t | \t\t|||||
| \t\t\t \xa0 \t\t\tParameter \t\t\t | \t\t\t\t\t\t \xa0 \t\t\tUnits \t\t\t | \t\t\t\t\t\t spleen \t\t\t | \t\t\t\t\t\t blood \t\t\t | \t\t||
| \t\t\t 9W/♂ \t\t\t | \t\t\t\t\t\t 9W/♀ \t\t\t | \t\t\t\t\t\t 9W/♂ \t\t\t | \t\t\t\t\t\t 9W/♀ \t\t\t | \t\t||
| \t\t\t B cells \t\t\t | \t\t\t\t\t\t \xa0 \t\t\t% of leukocytes \t\t\t | \t\t\t\t\t\t 79.55 \t\t\t | \t\t\t\t\t\t 74.43 \t\t\t | \t\t\t\t\t\t 48.55 \t\t\t | \t\t\t\t\t\t 30.30 \t\t\t | \t\t
| \t\t\t NK cells \t\t\t | \t\t\t\t\t\t 7.75 \t\t\t | \t\t\t\t\t\t 11.12 \t\t\t | \t\t\t\t\t\t 7.23 \t\t\t | \t\t\t\t\t\t 19.13 \t\t\t | \t\t|
| \t\t\t T cells \t\t\t | \t\t\t\t\t\t 0.35 \t\t\t | \t\t\t\t\t\t 0.54 \t\t\t | \t\t\t\t\t\t 0.38 \t\t\t | \t\t\t\t\t\t 0.84 \t\t\t | \t\t|
| \t\t\t immature B \t\t\t | \t\t\t\t\t\t \xa0 \t\t\t% of B cells \t\t\t | \t\t\t\t\t\t 51.23 \t\t\t | \t\t\t\t\t\t 45.30 \t\t\t | \t\t\t\t\t\t 41.28 \t\t\t | \t\t\t\t\t\t 23.37 \t\t\t | \t\t
| \t\t\t mature B \t\t\t | \t\t\t\t\t\t 28.38 \t\t\t | \t\t\t\t\t\t 29.30 \t\t\t | \t\t\t\t\t\t 7.58 \t\t\t | \t\t\t\t\t\t 7.17 \t\t\t | \t\t|
| \t\t\t CD4+ T \t\t\t | \t\t\t\t\t\t \xa0 \t\t\t% of T cells \t\t\t | \t\t\t\t\t\t 13.69 \t\t\t | \t\t\t\t\t\t 4.50 \t\t\t | \t\t\t\t\t\t 7.40 \t\t\t | \t\t\t\t\t\t 1.99 \t\t\t | \t\t
| \t\t\t CD8+ T \t\t\t | \t\t\t\t\t\t 39.83 \t\t\t | \t\t\t\t\t\t 45.63 \t\t\t | \t\t\t\t\t\t 46.55 \t\t\t | \t\t\t\t\t\t 49.40 \t\t\t | \t\t|
Flow cytometr
\t\t\t\xa0
\t\t\tParameter
\t\t\t\xa0
\t\t\tUnits
\t\t\tspleen
\t\t\tblood
\t\t\t9W/♂
\t\t\t9W/♀
\t\t\t9W/♂
\t\t\t9W/♀
\t\t\tB cells
\t\t\t\xa0
\t\t\t% of leukocytes
\t\t\t79.55
\t\t\t74.43
\t\t\t48.55
\t\t\t30.30
\t\t\tNK cells
\t\t\t7.75
\t\t\t11.12
\t\t\t7.23
\t\t\t19.13
\t\t\tT cells
\t\t\t0.35
\t\t\t0.54
\t\t\t0.38
\t\t\t0.84
\t\t\timmature B
\t\t\t\xa0
\t\t\t% of B cells
\t\t\t51.23
\t\t\t45.30
\t\t\t41.28
\t\t\t23.37
\t\t\tmature B
\t\t\t28.38
\t\t\t29.30
\t\t\t7.58
\t\t\t7.17
\t\t\tCD4+ T
\t\t\t\xa0
\t\t\t% of T cells
\t\t\t13.69
\t\t\t4.50
\t\t\t7.40
\t\t\t1.99
\t\t\tCD8+ T
\t\t\t39.83
\t\t\t45.63
\t\t\t46.55
\t\t\t49.40
\t\t\tFlow cytometr
\t\t\tFlow cytometr
\t\t\tFlow cytometr
Flow cytometrFlow cytometrFlow cytometrFlow cytometrFlow cytometrFlow cytometr\t\t\t\t\t\t\t\xa0
\t\t\tParameter
\t\t\t\xa0
\t\t\tUnits
\t\t\tspleen
\t\t\tblood
\t\t\t\xa0
\t\t\tParameter
\t\t\t\xa0
\xa0\t\t\tParameter
ParameterParameterParameterParameter\t\t\t\t\t\t\xa0
\t\t\tUnits
\t\t\t\xa0
\xa0\t\t\tUnits
UnitsUnitsUnitsUnits\t\t\t\t\t\tspleen
\t\t\tspleen
spleenspleenspleenspleen\t\t\t\t\t\tblood
\t\t\tblood
bloodbloodbloodblood\t\t\t\t\t\t\t9W/♂
\t\t\t9W/♀
\t\t\t9W/♂
\t\t\t9W/♀
\t\t\t9W/♂
\t\t\t9W/♂
9W/♂9W/♂9W/♂9W/♂\t\t\t\t\t\t9W/♀
\t\t\t9W/♀
9W/♀9W/♀9W/♀9W/♀\t\t\t\t\t\t9W/♂
\t\t\t9W/♂
9W/♂9W/♂9W/♂9W/♂\t\t\t\t\t\t9W/♀
\t\t\t9W/♀
9W/♀9W/♀9W/♀9W/♀\t\t\t\t\t\t\tB cells
\t\t\t\xa0
\t\t\t% of leukocytes
\t\t\t79.55
\t\t\t74.43
\t\t\t48.55
\t\t\t30.30
\t\t\tB cells
\t\t\tB cells
B cellsB cellsB cellsB cells\t\t\t\t\t\t\xa0
\t\t\t% of leukocytes
\t\t\t\xa0
\xa0\t\t\t% of leukocytes
% of leukocytes% of leukocytes% of leukocytes% of leukocytes\t\t\t\t\t\t79.55
\t\t\t79.55
79.5579.5579.5579.55\t\t\t\t\t\t74.43
\t\t\t74.43
74.4374.4374.4374.43\t\t\t\t\t\t48.55
\t\t\t48.55
48.5548.5548.5548.55\t\t\t\t\t\t30.30
\t\t\t30.30
30.3030.3030.3030.30\t\t\t\t\t\t\tNK cells
\t\t\t7.75
\t\t\t11.12
\t\t\t7.23
\t\t\t19.13
\t\t\tNK cells
\t\t\tNK cells
NK cellsNK cellsNK cellsNK cells\t\t\t\t\t\t7.75
\t\t\t7.75
7.757.757.757.75\t\t\t\t\t\t11.12
\t\t\t11.12
11.1211.1211.1211.12\t\t\t\t\t\t7.23
\t\t\t7.23
7.237.237.237.23\t\t\t\t\t\t19.13
\t\t\t19.13
19.1319.1319.1319.13\t\t\t\t\t\t\tT cells
\t\t\t0.35
\t\t\t0.54
\t\t\t0.38
\t\t\t0.84
\t\t\tT cells
\t\t\tT cells
T cellsT cellsT cellsT cells\t\t\t\t\t\t0.35
\t\t\t0.35
0.350.350.350.35\t\t\t\t\t\t0.54
\t\t\t0.54
0.540.540.540.54\t\t\t\t\t\t0.38
\t\t\t0.38
0.380.380.380.38\t\t\t\t\t\t0.84
\t\t\t0.84
0.840.840.840.84\t\t\t\t\t\t\timmature B
\t\t\t\xa0
\t\t\t% of B cells
\t\t\t51.23
\t\t\t45.30
\t\t\t41.28
\t\t\t23.37
\t\t\timmature B
\t\t\timmature B
immature Bimmature Bimmature Bimmature B\t\t\t\t\t\t\xa0
\t\t\t% of B cells
\t\t\t\xa0
\xa0\t\t\t% of B cells
% of B cells% of B cells% of B cells% of B cells\t\t\t\t\t\t51.23
\t\t\t51.23
51.2351.2351.2351.23\t\t\t\t\t\t45.30
\t\t\t45.30
45.3045.3045.3045.30\t\t\t\t\t\t41.28
\t\t\t41.28
41.2841.2841.2841.28\t\t\t\t\t\t23.37
\t\t\t23.37
23.3723.3723.3723.37\t\t\t\t\t\t\tmature B
\t\t\t28.38
\t\t\t29.30
\t\t\t7.58
\t\t\t7.17
\t\t\tmature B
\t\t\tmature B
mature Bmature Bmature Bmature B\t\t\t\t\t\t28.38
\t\t\t28.38
28.3828.3828.3828.38\t\t\t\t\t\t29.30
\t\t\t29.30
29.3029.3029.3029.30\t\t\t\t\t\t7.58
\t\t\t7.58
7.587.587.587.58\t\t\t\t\t\t7.17
\t\t\t7.17
7.177.177.177.17\t\t\t\t\t\t\tCD4+ T
\t\t\t\xa0
\t\t\t% of T cells
\t\t\t13.69
\t\t\t4.50
\t\t\t7.40
\t\t\t1.99
\t\t\tCD4+ T
\t\t\tCD4+ T
CD4+ TCD4+ TCD4+ TCD4+ T\t\t\t\t\t\t\xa0
\t\t\t% of T cells
\t\t\t\xa0
\xa0\t\t\t% of T cells
% of T cells% of T cells% of T cells% of T cells\t\t\t\t\t\t13.69
\t\t\t13.69
13.6913.6913.6913.69\t\t\t\t\t\t4.50
\t\t\t4.50
4.504.504.504.50\t\t\t\t\t\t7.40
\t\t\t7.40
7.407.407.407.40\t\t\t\t\t\t1.99
\t\t\t1.99
1.991.991.991.99\t\t\t\t\t\t\tCD8+ T
\t\t\t39.83
\t\t\t45.63
\t\t\t46.55
\t\t\t49.40
\t\t\tCD8+ T
\t\t\tCD8+ T
CD8+ TCD8+ TCD8+ TCD8+ T\t\t\t\t\t\t39.83
\t\t\t39.83
39.8339.8339.8339.83\t\t\t\t\t\t45.63
\t\t\t45.63
45.6345.6345.6345.63\t\t\t\t\t\t46.55
\t\t\t46.55
46.5546.5546.5546.55\t\t\t\t\t\t49.40
\t\t\t49.40
49.4049.4049.4049.40\t\t\t\t\t\t\xa0
\xa0参考文献
参考文献参考文献参考文献参考文献参考文献参考文献Craig S, Nowell¤a, Nicholas Bredenkamp, Ste ′phanie Tete ′lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):1–16.
\tLili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:5836–5847.
\tDarnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):57–64.
\t?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:1206–1215.
\tCraig S, Nowell¤a, Nicholas Bredenkamp, Ste ′phanie Tete ′lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):1–16.
\tCraig S, Nowell¤a, Nicholas Bredenkamp, Ste ′phanie Tete ′lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):1–16.
Craig S, Nowell¤a, Nicholas Bredenkamp, Ste ′phanie Tete ′lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):1–16.Craig S, Nowell¤a, Nicholas Bredenkamp, Ste ′phanie Tete ′lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):1–16.Craig S, NowellCraig S, NowellCraig S, Nowell¤¤¤¤a, Nicholas Bredenkamp, Ste a, Nicholas Bredenkamp, Ste a, Nicholas Bredenkamp, Ste ′′′′phanie Tete phanie Tete phanie Tete ′′′′lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):lin, et al., Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence. PLoS Genetics 2011, 7(11):111––––16.16.16.\t\tLili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:5836–5847.
\tLili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:5836–5847.
Lili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:5836–5847.Lili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:5836–5847.Lili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:Lili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:Lili Cheng, Jianfei Guo, Liguang Sun, et al., Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2010, 285:583658365836––––5847.5847.5847.\t\tDarnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):57–64.
\tDarnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):57–64.
Darnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):57–64.Darnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):57–64.Darnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):Darnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):Darnell DK, Zhang LS, Hannenhalli S, et al., Developmental expression of chicken FOXN1 and putative target genes during feather development. The International Journal of Developmental Biology 2014, 58(1):575757––––64.64.64.\t\t?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:1206–1215.
\t?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:1206–1215.
?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:1206–1215.?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:1206–1215.?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:?uklys S, Handel A, Zhanybekova S, et al., Foxn1 regulates key target genes essential for T cell development in postnatal thymicepithelial cells. Nature Immunology 2016, 17:120612061206––––1215.1215.1215.\t\xa0\xa0