\n 产品名称:GPS2 rabbit Polyclonal Antibody
产品货号:ATA30294
产品规格:100ug
免疫原:The antiserum was produced against synthesized peptide derived from human GPS2. AA range:11-60
宿主种属:Rabbit
反应种属:Human,Mouse,Rat
产品状态:Liquid
克隆性:Polyclonal
应用实验:WB: 1/500 - 1/2000. ELISA: 1/40000
纯化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
产品背景:G protein pathway suppressor 2(GPS2) Homo sapiens This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008],
存放条件:Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4 °C for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.
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