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\xa0ERRB2/Estrogen Related Receptor beta Antibody
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\xa0ERRB2/Estrogen Related Receptor beta Antibody\xa0ERRB2/Estrogen Related Receptor beta Antibody\xa0ERRB2/Estrogen Related Receptor beta Antibody
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Cat#：PL0300475
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Cat#：Cat#：PL0300475
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Isotype:Rabbit Polyclonal IgG
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Isotype:Isotype:Rabbit Polyclonal IgG
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Immunogen：Peptide derived from Hu Estrogen Related Receptor beta. \xa0
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Immunogen：Immunogen：Peptide derived from Hu Estrogen Related Receptor beta. \xa0
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Purification:\xa0Immunogen affinity purified
Storage Buffer:\xa0PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Purification:\xa0Purification:\xa0Immunogen affinity purified
Storage Buffer:\xa0Storage Buffer:\xa0PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：Background：
Estrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion.
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Alternate Names：
Err 2; ERR b; ERR B2; ERR beta 2; ERR beta; Err2; ERRB 2; ERRb; ERRB2; ERRbeta 2; ERRbeta; ESR L2; ESRL 2; ESRL2; ESRRB; Estrogen receptor like 2; Estrogen receptor related 2; Estrrb; Nr3b2; Nuclear receptor ERRB2; Orphan nuclear receptor; Steroid hormone receptor ERR 2; Steroid hormone receptor ERR2; ERR2_Hu.\xa0
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Estrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion.
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Alternate Names：
Err 2; ERR b; ERR B2; ERR beta 2; ERR beta; Err2; ERRB 2; ERRb; ERRB2; ERRbeta 2; ERRbeta; ESR L2; ESRL 2; ESRL2; ESRRB; Estrogen receptor like 2; Estrogen receptor related 2; Estrrb; Nr3b2; Nuclear receptor ERRB2; Orphan nuclear receptor; Steroid hormone receptor ERR 2; Steroid hormone receptor ERR2; ERR2_Hu.\xa0
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Alternate Names：
Alternate Names：Alternate Names：
Err 2; ERR b; ERR B2; ERR beta 2; ERR beta; Err2; ERRB 2; ERRb; ERRB2; ERRbeta 2; ERRbeta; ESR L2; ESRL 2; ESRL2; ESRRB; Estrogen receptor like 2; Estrogen receptor related 2; Estrrb; Nr3b2; Nuclear receptor ERRB2; Orphan nuclear receptor; Steroid hormone receptor ERR 2; Steroid hormone receptor ERR2; ERR2_Hu.\xa0
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Err 2; ERR b; ERR B2; ERR beta 2; ERR beta; Err2; ERRB 2; ERRb; ERRB2; ERRbeta 2; ERRbeta; ESR L2; ESRL 2; ESRL2; ESRRB; Estrogen receptor like 2; Estrogen receptor related 2; Estrrb; Nr3b2; Nuclear receptor ERRB2; Orphan nuclear receptor; Steroid hormone receptor ERR 2; Steroid hormone receptor ERR2; ERR2_Hu.\xa0
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Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Guinea Pig,
Specificity Reaction：Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Guinea Pig,
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Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100\xa0IHC: 1:100-500 IF: 1:100-500
Application Notes:Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100\xa0IHC: 1:100-500 IF: 1:100-500
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Storage ：
Storage ：Storage ：
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted.
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted.
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This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.This product for research use only, not for use in humans, therapeutic or diagnostic procedures.This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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PLlabs公司PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 \xa0CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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