\n Anti-SUMO2/SUMO3/SUMO4 antibodyAnti-SUMO2/SUMO3/SUMO4 antibody

Cat. No. \xa0\xa0 \xa0JC160378 \xa0 \xa0 \xa0 \xa0
Package\xa0\xa0 \xa025 μl/100 μl/200 μl
Storage\xa0\xa0 \xa0-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa0Anti-SUMO2/SUMO3/SUMO4 rabbit polyclonal antibody
Applications \xa0 \xa0\xa0\xa0 \xa0ELISA, WB, IHC\xa0
Immunogen \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa0Synthetic peptide of human SUMO2/SUMO3/SUMO4
Reactivity \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa0Human, Mouse
Content \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa00.4 mg/ml
Host species \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa0Rabbit
Ig class \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0\xa0 \xa0Immunogen-specific rabbit IgG
Purification \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa0Antigen affinity purification

Anti-SUMO2/SUMO3/SUMO4 antibodyAnti-SUMO2/SUMO3/SUMO4 antibody
Target information
Symbol \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa0SUMO2/SUMO3/SUMO4
Full name \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\xa0 \xa0SMT3 suppressor of mif two 3 homolog 2/3/4 (S. cerevisiae)
Synonyms\xa0\xa0 \xa0SMT3A, Smt3B, SMT3H1, SUMO-3; HSMT3, SMT3B, SUMO3, Smt3A, SMT3H2; IDDM5, SMT3H4, SUMO-4, dJ281H8.4
Swissprot\xa0\xa0 \xa0P61956/P55854/Q6EEV6

Target Background
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Anti-SUMO2/SUMO3/SUMO4 antibodyAnti-SUMO2/SUMO3/SUMO4 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human colon cancer
Recommended dilution: 100-300\xa0\xa0 \xa0Predicted cell location: Cytoplasm, Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 100-300