\n

\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t

英文名称	Decorin
中文名称	核心蛋白聚糖抗体
别\xa0\xa0\xa0\xa0名	Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG-S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B; PGS2_HUMAN\xa0\xa0
研究领域	转录调节因子\xa0\xa0
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse,\xa0Rat,\xa0 (predicted: Human,\xa0)
产品应用	WB=1:500-2000\xa0IHC-P=1:100-500\xa0（石蜡切片需做抗原修复） \t\t\tnot yet tested in other applications. \t\t\toptimal dilutions/concentrations should be determined by the end user.
分\xa0子\xa0量	36kDa
细胞定位	细胞外基质\xa0分泌型蛋白\xa0
性\xa0\xa0\xa0\xa0状	Liquid
浓\xa0\xa0\xa0\xa0度	1mg/ml
免\xa0疫\xa0原	KLH conjugated synthetic peptide derived from mouse Decorin:131-230/354\xa0
亚\xa0\xa0\xa0\xa0型	IgG
纯化方法	affinity purified by Protein A
储\xa0存\xa0液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B. \t\t\t \t\t\tFunction: \t\t\tMay affect the rate of fibrils formation. \t\t\t \t\t\tSubunit: \t\t\tBinds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity). Subcellular Location : Secreted, extracellular space, extracellular matrix. \t\t\t \t\t\tPost-translational modifications: \t\t\tThe attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin. \t\t\t \t\t\tDISEASE: \t\t\tDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance. \t\t\t \t\t\tSimilarity: \t\t\tBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. \t\t\tContains 12 LRR (leucine-rich) repeats. \t\t\t \t\t\tSWISS: \t\t\tP28654 \t\t\t \t\t\tGene ID: \t\t\t13179 \t\t\t \t\t\tDatabase links:\t\t\t Entrez Gene: 1634\xa0Human \t\t\t Entrez Gene: 13179\xa0Mouse \t\t\t Entrez Gene: 29139\xa0Rat \t\t\t Omim: 125255\xa0Human \t\t\t SwissProt: P07585\xa0Human \t\t\t SwissProt: P28654\xa0Mouse \t\t\t SwissProt: Q01129\xa0Rat \t\t\t Unigene: 728830\xa0Human \t\t\t Unigene: 56769\xa0Mouse \t\t\t Unigene: 106103\xa0Rat \t\t\t \t\t\t \t\t\tImportant Note: \t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. \t\t\t \t\t\t核心蛋白聚糖(decorin)属高分子蛋白多糖类，为蛋白聚糖(PG)的一种,是转化生长因子β(TGFβ)的拮抗剂。Decorin在调节细胞粘附、迁移、增殖、胶原纤维形成活性调节及对TGF-β的负反馈调节中起到一定的作用。

\t\t\t\t\t\t英文名称\t\t\tDecorin\t\t\t\t\t\t\t中文名称\t\t\t核心蛋白聚糖抗体\t\t\t\t\t\t\t别\xa0\xa0\xa0\xa0名\t\t\tBone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG-S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B; PGS2_HUMAN\xa0\xa0\t\t\t\t\t\t\t研究领域\t\t\t转录调节因子\xa0\xa0\t\t\t\t\t\t\t抗体来源\t\t\tRabbit\t\t\t\t\t\t\t克隆类型\t\t\tPolyclonal\t\t\t\t\t\t\t交叉反应\t\t\tMouse,\xa0Rat,\xa0 (predicted: Human,\xa0)\t\t\t\t\t\t\t产品应用\t\t\tWB=1:500-2000\xa0IHC-P=1:100-500\xa0（石蜡切片需做抗原修复）
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t\t\t分\xa0子\xa0量\t\t\t36kDa\t\t\t\t\t\t\t细胞定位\t\t\t细胞外基质\xa0分泌型蛋白\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0\xa0状\t\t\tLiquid\t\t\t\t\t\t\t浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml\t\t\t\t\t\t\t免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from mouse Decorin:131-230/354\xa0\t\t\t\t\t\t\t亚\xa0\xa0\xa0\xa0型\t\t\tIgG\t\t\t\t\t\t\t纯化方法\t\t\taffinity purified by Protein A\t\t\t\t\t\t\t储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t\t\t保存条件\t\t\tShipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.\t\t\t\t\t\t\tPubMed\t\t\tPubMed\t\t\t\t\t\t\t产品介绍\t\t\tDecorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B.
\t\t\t
\t\t\tFunction:
\t\t\tMay affect the rate of fibrils formation.
\t\t\t
\t\t\tSubunit:
\t\t\tBinds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity). Subcellular Location : Secreted, extracellular space, extracellular matrix.
\t\t\t
\t\t\tPost-translational modifications:
\t\t\tThe attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
\t\t\t
\t\t\tDISEASE:
\t\t\tDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
\t\t\t
\t\t\tSimilarity:
\t\t\tBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
\t\t\tContains 12 LRR (leucine-rich) repeats.
\t\t\t
\t\t\tSWISS:
\t\t\tP28654
\t\t\t
\t\t\tGene ID:
\t\t\t13179
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 1634\xa0Human

\t\t\t

Entrez Gene: 13179\xa0Mouse

\t\t\t

Entrez Gene: 29139\xa0Rat

\t\t\t

Omim: 125255\xa0Human

\t\t\t

SwissProt: P07585\xa0Human

\t\t\t

SwissProt: P28654\xa0Mouse

\t\t\t

SwissProt: Q01129\xa0Rat

\t\t\t

Unigene: 728830\xa0Human

\t\t\t

Unigene: 56769\xa0Mouse

\t\t\t

Unigene: 106103\xa0Rat

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
\t\t\t
\t\t\t核心蛋白聚糖(decorin)属高分子蛋白多糖类，为蛋白聚糖(PG)的一种,是转化生长因子β(TGFβ)的拮抗剂。Decorin在调节细胞粘附、迁移、增殖、胶原纤维形成活性调节及对TGF-β的负反馈调节中起到一定的作用。\t\t\t\t\t\t\t\t英文名称\t\t\tDecorin\t\t\t\t\t英文名称英文名称\t\t\tDecorinDecorin\t\t\t\t\t\t\t中文名称\t\t\t核心蛋白聚糖抗体\t\t\t\t\t中文名称中文名称\t\t\t核心蛋白聚糖抗体核心蛋白聚糖抗体\t\t\t\t\t\t\t别\xa0\xa0\xa0\xa0名\t\t\tBone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG-S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B; PGS2_HUMAN\xa0\xa0\t\t\t\t\t别\xa0\xa0\xa0\xa0名别\xa0\xa0\xa0\xa0名\t\t\tBone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG-S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B; PGS2_HUMAN\xa0\xa0Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG-S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B; PGS2_HUMAN\xa0\xa0\t\t\t\t\t\t\t研究领域\t\t\t转录调节因子\xa0\xa0\t\t\t\t\t研究领域研究领域\t\t\t转录调节因子\xa0\xa0转录调节因子\xa0\xa0\t\t\t\t\t\t\t抗体来源\t\t\tRabbit\t\t\t\t\t抗体来源抗体来源\t\t\tRabbitRabbit\t\t\t\t\t\t\t克隆类型\t\t\tPolyclonal\t\t\t\t\t克隆类型克隆类型\t\t\tPolyclonalPolyclonal\t\t\t\t\t\t\t交叉反应\t\t\tMouse,\xa0Rat,\xa0 (predicted: Human,\xa0)\t\t\t\t\t交叉反应交叉反应\t\t\tMouse,\xa0Rat,\xa0 (predicted: Human,\xa0)Mouse,\xa0Rat,\xa0 (predicted: Human,\xa0)\t\t\t\t\t\t\t产品应用\t\t\tWB=1:500-2000\xa0IHC-P=1:100-500\xa0（石蜡切片需做抗原修复）
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t产品应用产品应用\t\t\tWB=1:500-2000\xa0IHC-P=1:100-500\xa0（石蜡切片需做抗原修复）
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.WB=1:500-2000\xa0IHC-P=1:100-500\xa0（石蜡切片需做抗原修复）
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t\t\t分\xa0子\xa0量\t\t\t36kDa\t\t\t\t\t分\xa0子\xa0量分\xa0子\xa0量\t\t\t36kDa36kDa\t\t\t\t\t\t\t细胞定位\t\t\t细胞外基质\xa0分泌型蛋白\xa0\t\t\t\t\t细胞定位细胞定位\t\t\t细胞外基质\xa0分泌型蛋白\xa0细胞外基质\xa0分泌型蛋白\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0\xa0状\t\t\tLiquid\t\t\t\t\t性\xa0\xa0\xa0\xa0状性\xa0\xa0\xa0\xa0状\t\t\tLiquidLiquid\t\t\t\t\t\t\t浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml\t\t\t\t\t浓\xa0\xa0\xa0\xa0度浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml1mg/ml\t\t\t\t\t\t\t免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from mouse Decorin:131-230/354\xa0\t\t\t\t\t免\xa0疫\xa0原免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from mouse Decorin:131-230/354\xa0KLH conjugated synthetic peptide derived from mouse Decorin:131-230/354\xa0\t\t\t\t\t\t\t亚\xa0\xa0\xa0\xa0型\t\t\tIgG\t\t\t\t\t亚\xa0\xa0\xa0\xa0型亚\xa0\xa0\xa0\xa0型\t\t\tIgGIgG\t\t\t\t\t\t\t纯化方法\t\t\taffinity purified by Protein A\t\t\t\t\t纯化方法纯化方法\t\t\taffinity purified by Protein Aaffinity purified by Protein A\t\t\t\t\t\t\t储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t储\xa0存\xa0液储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t\t\t保存条件\t\t\tShipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.\t\t\t\t\t保存条件保存条件\t\t\tShipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.\t\t\t\t\t\t\tPubMed\t\t\tPubMed\t\t\t\t\tPubMedPubMed\t\t\tPubMedPubMedPubMed\t\t\t\t\t\t\t产品介绍\t\t\tDecorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B.
\t\t\t
\t\t\tFunction:
\t\t\tMay affect the rate of fibrils formation.
\t\t\t
\t\t\tSubunit:
\t\t\tBinds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity). Subcellular Location : Secreted, extracellular space, extracellular matrix.
\t\t\t
\t\t\tPost-translational modifications:
\t\t\tThe attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
\t\t\t
\t\t\tDISEASE:
\t\t\tDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
\t\t\t
\t\t\tSimilarity:
\t\t\tBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
\t\t\tContains 12 LRR (leucine-rich) repeats.
\t\t\t
\t\t\tSWISS:
\t\t\tP28654
\t\t\t
\t\t\tGene ID:
\t\t\t13179
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 1634\xa0Human

\t\t\t

Entrez Gene: 13179\xa0Mouse

\t\t\t

Entrez Gene: 29139\xa0Rat

\t\t\t

Omim: 125255\xa0Human

\t\t\t

SwissProt: P07585\xa0Human

\t\t\t

SwissProt: P28654\xa0Mouse

\t\t\t

SwissProt: Q01129\xa0Rat

\t\t\t

Unigene: 728830\xa0Human

\t\t\t

Unigene: 56769\xa0Mouse

\t\t\t

Unigene: 106103\xa0Rat

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
\t\t\t
\t\t\t核心蛋白聚糖(decorin)属高分子蛋白多糖类，为蛋白聚糖(PG)的一种,是转化生长因子β(TGFβ)的拮抗剂。Decorin在调节细胞粘附、迁移、增殖、胶原纤维形成活性调节及对TGF-β的负反馈调节中起到一定的作用。\t\t\t\t\t产品介绍产品介绍\t\t\tDecorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B.
\t\t\t
\t\t\tFunction:
\t\t\tMay affect the rate of fibrils formation.
\t\t\t
\t\t\tSubunit:
\t\t\tBinds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity). Subcellular Location : Secreted, extracellular space, extracellular matrix.
\t\t\t
\t\t\tPost-translational modifications:
\t\t\tThe attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
\t\t\t
\t\t\tDISEASE:
\t\t\tDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
\t\t\t
\t\t\tSimilarity:
\t\t\tBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
\t\t\tContains 12 LRR (leucine-rich) repeats.
\t\t\t
\t\t\tSWISS:
\t\t\tP28654
\t\t\t
\t\t\tGene ID:
\t\t\t13179
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 1634\xa0Human

\t\t\t

Entrez Gene: 13179\xa0Mouse

\t\t\t

Entrez Gene: 29139\xa0Rat

\t\t\t

Omim: 125255\xa0Human

\t\t\t

SwissProt: P07585\xa0Human

\t\t\t

SwissProt: P28654\xa0Mouse

\t\t\t

SwissProt: Q01129\xa0Rat

\t\t\t

Unigene: 728830\xa0Human

\t\t\t

Unigene: 56769\xa0Mouse

\t\t\t

Unigene: 106103\xa0Rat

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
\t\t\t
\t\t\t核心蛋白聚糖(decorin)属高分子蛋白多糖类，为蛋白聚糖(PG)的一种,是转化生长因子β(TGFβ)的拮抗剂。Decorin在调节细胞粘附、迁移、增殖、胶原纤维形成活性调节及对TGF-β的负反馈调节中起到一定的作用。Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B.
\t\t\t
\t\t\tFunction:
\t\t\tMay affect the rate of fibrils formation.
\t\t\t
\t\t\tSubunit:
\t\t\tBinds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity). Subcellular Location : Secreted, extracellular space, extracellular matrix.
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\t\t\tPost-translational modifications:
\t\t\tThe attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
\t\t\t
\t\t\tDISEASE:
\t\t\tDefects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
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\t\t\tSimilarity:
\t\t\tBelongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
\t\t\tContains 12 LRR (leucine-rich) repeats.
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\t\t\tSWISS:
\t\t\tP28654
\t\t\t
\t\t\tGene ID:
\t\t\t13179
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 1634\xa0Human

Entrez Gene: 1634Entrez Gene: 1634\xa0Human\t\t\t

Entrez Gene: 13179\xa0Mouse

Entrez Gene: 13179Entrez Gene: 13179\xa0Mouse\t\t\t

Entrez Gene: 29139\xa0Rat

Entrez Gene: 29139Entrez Gene: 29139\xa0Rat\t\t\t

Omim: 125255\xa0Human

Omim: 125255Omim: 125255\xa0Human\t\t\t

SwissProt: P07585\xa0Human

SwissProt: P07585SwissProt: P07585\xa0Human\t\t\t

SwissProt: P28654\xa0Mouse

SwissProt: P28654SwissProt: P28654\xa0Mouse\t\t\t

SwissProt: Q01129\xa0Rat

SwissProt: Q01129SwissProt: Q01129\xa0Rat\t\t\t

Unigene: 728830\xa0Human

Unigene: 728830Unigene: 728830\xa0Human\t\t\t

Unigene: 56769\xa0Mouse

Unigene: 56769Unigene: 56769\xa0Mouse\t\t\t

Unigene: 106103\xa0Rat

Unigene: 106103Unigene: 106103\xa0Rat\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
\t\t\t
\t\t\t核心蛋白聚糖(decorin)属高分子蛋白多糖类，为蛋白聚糖(PG)的一种,是转化生长因子β(TGFβ)的拮抗剂。Decorin在调节细胞粘附、迁移、增殖、胶原纤维形成活性调节及对TGF-β的负反馈调节中起到一定的作用。\t\t\t

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