\n GPM6A神经细胞膜糖蛋白M6a抗体GPM6A神经细胞膜糖蛋白M6a抗体GPM6A神经细胞膜糖蛋白M6a抗体

\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t

英文名称	GPM6A
中文名称	神经细胞膜糖蛋白M6a抗体
别\xa0\xa0\xa0\xa0名	GPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.\xa0\xa0
规格价格	100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价
说\xa0明\xa0书	100ul\xa0\xa0200ul
研究领域	细胞生物\xa0\xa0神经生物学\xa0\xa0
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,\xa0Mouse,\xa0Rat,\xa0Dog,\xa0Rabbit,\xa0
产品应用	WB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0Flow-Cyt=1μg/Test\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0 \t\t\tnot yet tested in other applications. \t\t\toptimal dilutions/concentrations should be determined by the end user.
分\xa0子\xa0量	31kDa
细胞定位	细胞膜\xa0
性\xa0\xa0\xa0\xa0状	Lyophilized or Liquid
浓\xa0\xa0\xa0\xa0度	1mg/ml
免\xa0疫\xa0原	KLH conjugated synthetic peptide derived from human GPM6A:151-250/278\xa0<Extracellular>
亚\xa0\xa0\xa0\xa0型	IgG
纯化方法	affinity purified by Protein A
储\xa0存\xa0液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: \t\t\tGPM6A (Glycoprotein M6A) is a Protein Coding gene. GO annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B. \t\t\t \t\t\tFunction: \t\t\tInvolved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type ****** receptor. \t\t\t \t\t\tSubunit: \t\t\tInteracts with OPRM1\xa0 \t\t\t \t\t\tSubcellular Location: \t\t\tCell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons. \t\t\t \t\t\tSimilarity: \t\t\tBelongs to the myelin proteolipid protein family. \t\t\t \t\t\tSWISS: \t\t\tP51674 \t\t\t \t\t\tGene ID: \t\t\t2823 \t\t\t \t\t\tDatabase links:\t\t\t Entrez Gene: 2823\xa0Human \t\t\t Entrez Gene: 234267\xa0Mouse \t\t\t Omim: 601275\xa0Human \t\t\t SwissProt: P51674\xa0Human \t\t\t SwissProt: P35802\xa0Mouse \t\t\t Unigene: 75819\xa0Human \t\t\t Unigene: 241700\xa0Mouse \t\t\t \t\t\t \t\t\tImportant Note: \t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0 \t\t\t\xa0
产品图片	\t\t\tSample:\xa0 \t\t\tCerebrum (Mouse) Lysate at 40 ug \t\t\tPrimary: Anti-GPM6A (bs-10757R) at 1/1000 dilution \t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution \t\t\tPredicted band size: 31 kD \t\t\tObserved band size: 31 kD \t\t\t \t\t\t \t\t\tBlank control: RSC96(blue), the cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice. \t\t\tIsotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 0.2μg in 100 μL1X PBS containing 0.5% BSA(green).

\t\t\t\t\t\t英文名称\t\t\tGPM6A\t\t\t\t\t\t\t中文名称\t\t\t神经细胞膜糖蛋白M6a抗体\t\t\t\t\t\t\t别\xa0\xa0\xa0\xa0名\t\t\tGPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.\xa0\xa0\t\t\t\t\t\t\t规格价格\t\t\t100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价\t\t\t\t\t\t\t说\xa0明\xa0书\t\t\t100ul\xa0\xa0200ul\t\t\t\t\t\t\t研究领域\t\t\t细胞生物\xa0\xa0神经生物学\xa0\xa0\t\t\t\t\t\t\t抗体来源\t\t\tRabbit\t\t\t\t\t\t\t克隆类型\t\t\tPolyclonal\t\t\t\t\t\t\t交叉反应\t\t\tHuman,\xa0Mouse,\xa0Rat,\xa0Dog,\xa0Rabbit,\xa0\t\t\t\t\t\t\t产品应用\t\t\tWB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0Flow-Cyt=1μg/Test\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t\t\t分\xa0子\xa0量\t\t\t31kDa\t\t\t\t\t\t\t细胞定位\t\t\t细胞膜\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0\xa0状\t\t\tLyophilized or Liquid\t\t\t\t\t\t\t浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml\t\t\t\t\t\t\t免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from human GPM6A:151-250/278\xa0<Extracellular>\t\t\t\t\t\t\t亚\xa0\xa0\xa0\xa0型\t\t\tIgG\t\t\t\t\t\t\t纯化方法\t\t\taffinity purified by Protein A\t\t\t\t\t\t\t储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t\t\t保存条件\t\t\tStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\t\t\t\t\t\t\tPubMed\t\t\tPubMed\t\t\t\t\t\t\t产品介绍\t\t\tbackground:
\t\t\tGPM6A (Glycoprotein M6A) is a Protein Coding gene. GO annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B.
\t\t\t
\t\t\tFunction:
\t\t\tInvolved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type ****** receptor.
\t\t\t
\t\t\tSubunit:
\t\t\tInteracts with OPRM1\xa0
\t\t\t
\t\t\tSubcellular Location:
\t\t\tCell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons.
\t\t\t
\t\t\tSimilarity:
\t\t\tBelongs to the myelin proteolipid protein family.
\t\t\t
\t\t\tSWISS:
\t\t\tP51674
\t\t\t
\t\t\tGene ID:
\t\t\t2823
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 2823\xa0Human

\t\t\t

Entrez Gene: 234267\xa0Mouse

\t\t\t

Omim: 601275\xa0Human

\t\t\t

SwissProt: P51674\xa0Human

\t\t\t

SwissProt: P35802\xa0Mouse

\t\t\t

Unigene: 75819\xa0Human

\t\t\t

Unigene: 241700\xa0Mouse

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t\xa0\t\t\t\t\t\t\t产品图片\t\t\t
\t\t\tSample:\xa0
\t\t\tCerebrum (Mouse) Lysate at 40 ug
\t\t\tPrimary: Anti-GPM6A (bs-10757R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 31 kD
\t\t\tObserved band size: 31 kD
\t\t\t
\t\t\t
\t\t\tBlank control: RSC96(blue), the cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice.
\t\t\tIsotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 0.2μg in 100 μL1X PBS containing 0.5% BSA(green).\t\t\t\t\t\t\t\t英文名称\t\t\tGPM6A\t\t\t\t\t英文名称英文名称\t\t\tGPM6AGPM6A\t\t\t\t\t\t\t中文名称\t\t\t神经细胞膜糖蛋白M6a抗体\t\t\t\t\t中文名称中文名称\t\t\t神经细胞膜糖蛋白M6a抗体神经细胞膜糖蛋白M6a抗体\t\t\t\t\t\t\t别\xa0\xa0\xa0\xa0名\t\t\tGPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.\xa0\xa0\t\t\t\t\t别\xa0\xa0\xa0\xa0名别\xa0\xa0\xa0\xa0名\t\t\tGPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.\xa0\xa0GPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.\xa0\xa0\t\t\t\t\t\t\t规格价格\t\t\t100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价\t\t\t\t\t规格价格规格价格\t\t\t100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价\t\t\t\t\t\t\t说\xa0明\xa0书\t\t\t100ul\xa0\xa0200ul\t\t\t\t\t说\xa0明\xa0书说\xa0明\xa0书\t\t\t100ul\xa0\xa0200ul100ul\xa0\xa0200ul\t\t\t\t\t\t\t研究领域\t\t\t细胞生物\xa0\xa0神经生物学\xa0\xa0\t\t\t\t\t研究领域研究领域\t\t\t细胞生物\xa0\xa0神经生物学\xa0\xa0细胞生物\xa0\xa0神经生物学\xa0\xa0\t\t\t\t\t\t\t抗体来源\t\t\tRabbit\t\t\t\t\t抗体来源抗体来源\t\t\tRabbitRabbit\t\t\t\t\t\t\t克隆类型\t\t\tPolyclonal\t\t\t\t\t克隆类型克隆类型\t\t\tPolyclonalPolyclonal\t\t\t\t\t\t\t交叉反应\t\t\tHuman,\xa0Mouse,\xa0Rat,\xa0Dog,\xa0Rabbit,\xa0\t\t\t\t\t交叉反应交叉反应\t\t\tHuman,\xa0Mouse,\xa0Rat,\xa0Dog,\xa0Rabbit,\xa0Human,\xa0Mouse,\xa0Rat,\xa0Dog,\xa0Rabbit,\xa0\t\t\t\t\t\t\t产品应用\t\t\tWB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0Flow-Cyt=1μg/Test\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t产品应用产品应用\t\t\tWB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0Flow-Cyt=1μg/Test\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.WB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0Flow-Cyt=1μg/Test\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t\t\t分\xa0子\xa0量\t\t\t31kDa\t\t\t\t\t分\xa0子\xa0量分\xa0子\xa0量\t\t\t31kDa31kDa\t\t\t\t\t\t\t细胞定位\t\t\t细胞膜\xa0\t\t\t\t\t细胞定位细胞定位\t\t\t细胞膜\xa0细胞膜\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0\xa0状\t\t\tLyophilized or Liquid\t\t\t\t\t性\xa0\xa0\xa0\xa0状性\xa0\xa0\xa0\xa0状\t\t\tLyophilized or LiquidLyophilized or Liquid\t\t\t\t\t\t\t浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml\t\t\t\t\t浓\xa0\xa0\xa0\xa0度浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml1mg/ml\t\t\t\t\t\t\t免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from human GPM6A:151-250/278\xa0<Extracellular>\t\t\t\t\t免\xa0疫\xa0原免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from human GPM6A:151-250/278\xa0<Extracellular>KLH conjugated synthetic peptide derived from human GPM6A:151-250/278\xa0\t\t\t\t\t\t\t亚\xa0\xa0\xa0\xa0型\t\t\tIgG\t\t\t\t\t亚\xa0\xa0\xa0\xa0型亚\xa0\xa0\xa0\xa0型\t\t\tIgGIgG\t\t\t\t\t\t\t纯化方法\t\t\taffinity purified by Protein A\t\t\t\t\t纯化方法纯化方法\t\t\taffinity purified by Protein Aaffinity purified by Protein A\t\t\t\t\t\t\t储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t储\xa0存\xa0液储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t\t\t保存条件\t\t\tStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\t\t\t\t\t保存条件保存条件\t\t\tStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\t\t\t\t\t\t\tPubMed\t\t\tPubMed\t\t\t\t\tPubMedPubMed\t\t\tPubMedPubMed\t\t\t\t\t\t\t产品介绍\t\t\tbackground:
\t\t\tGPM6A (Glycoprotein M6A) is a Protein Coding gene. GO annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B.
\t\t\t
\t\t\tFunction:
\t\t\tInvolved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type ****** receptor.
\t\t\t
\t\t\tSubunit:
\t\t\tInteracts with OPRM1\xa0
\t\t\t
\t\t\tSubcellular Location:
\t\t\tCell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons.
\t\t\t
\t\t\tSimilarity:
\t\t\tBelongs to the myelin proteolipid protein family.
\t\t\t
\t\t\tSWISS:
\t\t\tP51674
\t\t\t
\t\t\tGene ID:
\t\t\t2823
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 2823\xa0Human

\t\t\t

Entrez Gene: 234267\xa0Mouse

\t\t\t

Omim: 601275\xa0Human

\t\t\t

SwissProt: P51674\xa0Human

\t\t\t

SwissProt: P35802\xa0Mouse

\t\t\t

Unigene: 75819\xa0Human

\t\t\t

Unigene: 241700\xa0Mouse

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t\xa0\t\t\t\t\t产品介绍产品介绍\t\t\tbackground:
\t\t\tGPM6A (Glycoprotein M6A) is a Protein Coding gene. GO annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B.
\t\t\t
\t\t\tFunction:
\t\t\tInvolved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type ****** receptor.
\t\t\t
\t\t\tSubunit:
\t\t\tInteracts with OPRM1\xa0
\t\t\t
\t\t\tSubcellular Location:
\t\t\tCell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons.
\t\t\t
\t\t\tSimilarity:
\t\t\tBelongs to the myelin proteolipid protein family.
\t\t\t
\t\t\tSWISS:
\t\t\tP51674
\t\t\t
\t\t\tGene ID:
\t\t\t2823
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 2823\xa0Human

\t\t\t

Entrez Gene: 234267\xa0Mouse

\t\t\t

Omim: 601275\xa0Human

\t\t\t

SwissProt: P51674\xa0Human

\t\t\t

SwissProt: P35802\xa0Mouse

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Unigene: 75819\xa0Human

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Unigene: 241700\xa0Mouse

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\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t\xa0background:
\t\t\tGPM6A (Glycoprotein M6A) is a Protein Coding gene. GO annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B.
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\t\t\tFunction:
\t\t\tInvolved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type ****** receptor.
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\t\t\tSubunit:
\t\t\tInteracts with OPRM1\xa0
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\t\t\tSubcellular Location:
\t\t\tCell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons.
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\t\t\tSimilarity:
\t\t\tBelongs to the myelin proteolipid protein family.
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\t\t\tSWISS:
\t\t\tP51674
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\t\t\tGene ID:
\t\t\t2823
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\t\t\tDatabase links:\t\t\t

Entrez Gene: 2823\xa0Human

Entrez Gene: 2823\xa0Human\t\t\t

Entrez Gene: 234267\xa0Mouse

Entrez Gene: 234267\xa0Mouse\t\t\t

Omim: 601275\xa0Human

Omim: 601275\xa0Human\t\t\t

SwissProt: P51674\xa0Human

SwissProt: P51674\xa0Human\t\t\t

SwissProt: P35802\xa0Mouse

SwissProt: P35802\xa0Mouse\t\t\t

Unigene: 75819\xa0Human

Unigene: 75819\xa0Human\t\t\t

Unigene: 241700\xa0Mouse

Unigene: 241700\xa0Mouse\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t\xa0\t\t\t\t\t\t\t产品图片\t\t\t
\t\t\tSample:\xa0
\t\t\tCerebrum (Mouse) Lysate at 40 ug
\t\t\tPrimary: Anti-GPM6A (bs-10757R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 31 kD
\t\t\tObserved band size: 31 kD
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\t\t\tBlank control: RSC96(blue), the cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice.
\t\t\tIsotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 0.2μg in 100 μL1X PBS containing 0.5% BSA(green).\t\t\t\t\t产品图片产品图片\t\t\t
\t\t\tSample:\xa0
\t\t\tCerebrum (Mouse) Lysate at 40 ug
\t\t\tPrimary: Anti-GPM6A (bs-10757R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 31 kD
\t\t\tObserved band size: 31 kD
\t\t\t
\t\t\t
\t\t\tBlank control: RSC96(blue), the cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice.
\t\t\tIsotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 0.2μg in 100 μL1X PBS containing 0.5% BSA(green).
\t\t\tSample:\xa0
\t\t\tCerebrum (Mouse) Lysate at 40 ug
\t\t\tPrimary: Anti-GPM6A (bs-10757R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 31 kD
\t\t\tObserved band size: 31 kD
\t\t\t
\t\t\t
\t\t\tBlank control: RSC96(blue), the cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice.
\t\t\tIsotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 0.2μg in 100 μL1X PBS containing 0.5% BSA(green).