\n Galectin 3半乳糖凝集素3抗体Galectin 3半乳糖凝集素3抗体Galectin 3半乳糖凝集素3抗体

\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t

英文名称	Galectin 3
中文名称	半乳糖凝集素3抗体
别\xa0\xa0\xa0\xa0名	Galectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387;Galectin- 3; LEG3_HUMAN.\xa0\xa0
规格价格	100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价
说\xa0明\xa0书	100ul\xa0\xa0200ul
研究领域	肿瘤\xa0\xa0细胞生物\xa0\xa0免疫学\xa0\xa0细胞凋亡\xa0\xa0细胞粘附分子\xa0\xa0
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,\xa0Rat,\xa0
产品应用	WB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0 \t\t\tnot yet tested in other applications. \t\t\toptimal dilutions/concentrations should be determined by the end user.
分\xa0子\xa0量	29kDa
细胞定位	细胞核\xa0细胞浆\xa0分泌型蛋白\xa0
性\xa0\xa0\xa0\xa0状	Lyophilized or Liquid
浓\xa0\xa0\xa0\xa0度	1mg/ml
免\xa0疫\xa0原	KLH conjugated synthetic peptide derived from human Galectin 3:121-200/250\xa0
亚\xa0\xa0\xa0\xa0型	IgG
纯化方法	affinity purified by Protein A
储\xa0存\xa0液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: \t\t\tThis gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]. \t\t\t \t\t\tFunction: \t\t\tGalactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. \t\t\t \t\t\tSubunit: \t\t\tProbably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA. \t\t\t \t\t\tSubcellular Location: \t\t\tCytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface. \t\t\t \t\t\tTissue Specificity: \t\t\tA major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. \t\t\t \t\t\tSimilarity: \t\t\tContains 1 galectin domain. \t\t\t \t\t\tSWISS: \t\t\tP17931 \t\t\t \t\t\tGene ID: \t\t\t3958 \t\t\t \t\t\tDatabase links:\t\t\t Entrez Gene: 3958\xa0Human \t\t\t Entrez Gene: 16854\xa0Mouse \t\t\t Entrez Gene: 83781\xa0Rat \t\t\t Omim: 153619\xa0Human \t\t\t SwissProt: P17931\xa0Human \t\t\t SwissProt: P16110\xa0Mouse \t\t\t SwissProt: P08699\xa0Rat \t\t\t Unigene: 531081\xa0Human \t\t\t Unigene: 248615\xa0Mouse \t\t\t Unigene: 764\xa0Rat \t\t\t \t\t\t \t\t\tImportant Note: \t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0 \t\t\t \t\t\tGalectin-3是Galectin（半乳凝素）家族的一员，能识别糖蛋白和糖脂的特异性低聚糖结构，参与多种生理和病理过程，包括细胞生长和凋亡、细胞黏附、新生血管形成和肿瘤浸润与转移等。Galectin-3在肿瘤的发生、发展及转移中起重要作用。 \t\t\tGalectin-3在某些肿瘤组织中高表达，其在不同类型肿瘤，如结直肠癌、胃癌、胰腺癌、甲状腺癌及肺癌等患者中的高表达水平，与低生存、肿瘤复发、预后差及对化疗药物敏感性降低相关对于某些肿瘤，Galectin-3有可能成为一个有价值的诊断标志和治疗靶点。
产品图片	\t\t\tSample:MCF-7(human) Cell Lysate at 40 ug \t\t\tPrimary: Anti-Galectin 3 (bs-20699R) at 1/300 dilution \t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution \t\t\tPredicted band size: 29 kD \t\t\tObserved band size: 27 kD \t\t\t \t\t\t \t\t\tSample:\xa0 \t\t\tHela(Human) Cell Lysate at 30 ug \t\t\tHela KO Galectin3 (Human) Cell Lysate at 30 ug \t\t\tPrimary: Anti- Galectin3 (bs-20699R) at 1/1000 dilution \t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution \t\t\tPredicted band size: 29 kD \t\t\tObserved band size: 29 kD \t\t\t \t\t\t \t\t\tSample:\xa0 \t\t\tHela Cell (Human) Lysate at 40 ug \t\t\tMCF-7 Cell (Human) Lysate at 40 ug \t\t\tPrimary: Anti- Galectin 3 (bs-20699R) at 1/300 dilution \t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution \t\t\tPredicted band size: 29 kD \t\t\tObserved band size: 29 kD \t\t\t \t\t\t \t\t\tSample: MCF-7(Human) Cell Lysate at 30 ug \t\t\tPrimary: Anti-Galectin 3 (bs-20699R-HRP) at 1/1000 dilution \t\t\tPredicted band size: 29 kD \t\t\tObserved band size: 29 kD

\t\t\t\t\t\t英文名称\t\t\tGalectin 3\t\t\t\t\t\t\t中文名称\t\t\t半乳糖凝集素3抗体\t\t\t\t\t\t\t别\xa0\xa0\xa0\xa0名\t\t\tGalectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387;Galectin- 3; LEG3_HUMAN.\xa0\xa0\t\t\t\t\t\t\t规格价格\t\t\t100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价\t\t\t\t\t\t\t说\xa0明\xa0书\t\t\t100ul\xa0\xa0200ul\t\t\t\t\t\t\t研究领域\t\t\t肿瘤\xa0\xa0细胞生物\xa0\xa0免疫学\xa0\xa0细胞凋亡\xa0\xa0细胞粘附分子\xa0\xa0\t\t\t\t\t\t\t抗体来源\t\t\tRabbit\t\t\t\t\t\t\t克隆类型\t\t\tPolyclonal\t\t\t\t\t\t\t交叉反应\t\t\tHuman,\xa0Rat,\xa0\t\t\t\t\t\t\t产品应用\t\t\tWB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t\t\t分\xa0子\xa0量\t\t\t29kDa\t\t\t\t\t\t\t细胞定位\t\t\t细胞核\xa0细胞浆\xa0分泌型蛋白\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0\xa0状\t\t\tLyophilized or Liquid\t\t\t\t\t\t\t浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml\t\t\t\t\t\t\t免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from human Galectin 3:121-200/250\xa0\t\t\t\t\t\t\t亚\xa0\xa0\xa0\xa0型\t\t\tIgG\t\t\t\t\t\t\t纯化方法\t\t\taffinity purified by Protein A\t\t\t\t\t\t\t储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t\t\t保存条件\t\t\tStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\t\t\t\t\t\t\tPubMed\t\t\tPubMed\t\t\t\t\t\t\t产品介绍\t\t\tbackground:
\t\t\tThis gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
\t\t\t
\t\t\tFunction:
\t\t\tGalactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
\t\t\t
\t\t\tSubunit:
\t\t\tProbably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.
\t\t\t
\t\t\tSubcellular Location:
\t\t\tCytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
\t\t\t
\t\t\tTissue Specificity:
\t\t\tA major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
\t\t\t
\t\t\tSimilarity:
\t\t\tContains 1 galectin domain.
\t\t\t
\t\t\tSWISS:
\t\t\tP17931
\t\t\t
\t\t\tGene ID:
\t\t\t3958
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 3958\xa0Human

\t\t\t

Entrez Gene: 16854\xa0Mouse

\t\t\t

Entrez Gene: 83781\xa0Rat

\t\t\t

Omim: 153619\xa0Human

\t\t\t

SwissProt: P17931\xa0Human

\t\t\t

SwissProt: P16110\xa0Mouse

\t\t\t

SwissProt: P08699\xa0Rat

\t\t\t

Unigene: 531081\xa0Human

\t\t\t

Unigene: 248615\xa0Mouse

\t\t\t

Unigene: 764\xa0Rat

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t
\t\t\tGalectin-3是Galectin（半乳凝素）家族的一员，能识别糖蛋白和糖脂的特异性低聚糖结构，参与多种生理和病理过程，包括细胞生长和凋亡、细胞黏附、新生血管形成和肿瘤浸润与转移等。Galectin-3在肿瘤的发生、发展及转移中起重要作用。
\t\t\tGalectin-3在某些肿瘤组织中高表达，其在不同类型肿瘤，如结直肠癌、胃癌、胰腺癌、甲状腺癌及肺癌等患者中的高表达水平，与低生存、肿瘤复发、预后差及对化疗药物敏感性降低相关对于某些肿瘤，Galectin-3有可能成为一个有价值的诊断标志和治疗靶点。\t\t\t\t\t\t\t产品图片\t\t\t
\t\t\tSample:MCF-7(human) Cell Lysate at 40 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 27 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela(Human) Cell Lysate at 30 ug
\t\t\tHela KO Galectin3 (Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti- Galectin3 (bs-20699R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela Cell (Human) Lysate at 40 ug
\t\t\tMCF-7 Cell (Human) Lysate at 40 ug
\t\t\tPrimary: Anti- Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample: MCF-7(Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R-HRP) at 1/1000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD\t\t\t\t\t\t\t\t英文名称\t\t\tGalectin 3\t\t\t\t\t英文名称英文名称\t\t\tGalectin 3Galectin 3\t\t\t\t\t\t\t中文名称\t\t\t半乳糖凝集素3抗体\t\t\t\t\t中文名称中文名称\t\t\t半乳糖凝集素3抗体半乳糖凝集素3抗体\t\t\t\t\t\t\t别\xa0\xa0\xa0\xa0名\t\t\tGalectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387;Galectin- 3; LEG3_HUMAN.\xa0\xa0\t\t\t\t\t别\xa0\xa0\xa0\xa0名别\xa0\xa0\xa0\xa0名\t\t\tGalectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387;Galectin- 3; LEG3_HUMAN.\xa0\xa0Galectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387;Galectin- 3; LEG3_HUMAN.\xa0\xa0\t\t\t\t\t\t\t规格价格\t\t\t100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价\t\t\t\t\t规格价格规格价格\t\t\t100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价100ul/1380元\xa0购买\xa0\xa0\xa0\xa0200ul/2200元\xa0购买\xa0\xa0\xa0\xa0大包装/询价\t\t\t\t\t\t\t说\xa0明\xa0书\t\t\t100ul\xa0\xa0200ul\t\t\t\t\t说\xa0明\xa0书说\xa0明\xa0书\t\t\t100ul\xa0\xa0200ul100ul\xa0\xa0200ul\t\t\t\t\t\t\t研究领域\t\t\t肿瘤\xa0\xa0细胞生物\xa0\xa0免疫学\xa0\xa0细胞凋亡\xa0\xa0细胞粘附分子\xa0\xa0\t\t\t\t\t研究领域研究领域\t\t\t肿瘤\xa0\xa0细胞生物\xa0\xa0免疫学\xa0\xa0细胞凋亡\xa0\xa0细胞粘附分子\xa0\xa0肿瘤\xa0\xa0细胞生物\xa0\xa0免疫学\xa0\xa0细胞凋亡\xa0\xa0细胞粘附分子\xa0\xa0\t\t\t\t\t\t\t抗体来源\t\t\tRabbit\t\t\t\t\t抗体来源抗体来源\t\t\tRabbitRabbit\t\t\t\t\t\t\t克隆类型\t\t\tPolyclonal\t\t\t\t\t克隆类型克隆类型\t\t\tPolyclonalPolyclonal\t\t\t\t\t\t\t交叉反应\t\t\tHuman,\xa0Rat,\xa0\t\t\t\t\t交叉反应交叉反应\t\t\tHuman,\xa0Rat,\xa0Human,\xa0Rat,\xa0\t\t\t\t\t\t\t产品应用\t\t\tWB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t产品应用产品应用\t\t\tWB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.WB=1:500-2000\xa0ELISA=1:500-1000\xa0IHC-P=1:400-800\xa0IHC-F=1:400-800\xa0ICC=1:100-500\xa0IF=1:100-500\xa0（石蜡切片需做抗原修复）\xa0
\t\t\tnot yet tested in other applications.
\t\t\toptimal dilutions/concentrations should be determined by the end user.\t\t\t\t\t\t\t分\xa0子\xa0量\t\t\t29kDa\t\t\t\t\t分\xa0子\xa0量分\xa0子\xa0量\t\t\t29kDa29kDa\t\t\t\t\t\t\t细胞定位\t\t\t细胞核\xa0细胞浆\xa0分泌型蛋白\xa0\t\t\t\t\t细胞定位细胞定位\t\t\t细胞核\xa0细胞浆\xa0分泌型蛋白\xa0细胞核\xa0细胞浆\xa0分泌型蛋白\xa0\t\t\t\t\t\t\t性\xa0\xa0\xa0\xa0状\t\t\tLyophilized or Liquid\t\t\t\t\t性\xa0\xa0\xa0\xa0状性\xa0\xa0\xa0\xa0状\t\t\tLyophilized or LiquidLyophilized or Liquid\t\t\t\t\t\t\t浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml\t\t\t\t\t浓\xa0\xa0\xa0\xa0度浓\xa0\xa0\xa0\xa0度\t\t\t1mg/ml1mg/ml\t\t\t\t\t\t\t免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from human Galectin 3:121-200/250\xa0\t\t\t\t\t免\xa0疫\xa0原免\xa0疫\xa0原\t\t\tKLH conjugated synthetic peptide derived from human Galectin 3:121-200/250\xa0KLH conjugated synthetic peptide derived from human Galectin 3:121-200/250\xa0\t\t\t\t\t\t\t亚\xa0\xa0\xa0\xa0型\t\t\tIgG\t\t\t\t\t亚\xa0\xa0\xa0\xa0型亚\xa0\xa0\xa0\xa0型\t\t\tIgGIgG\t\t\t\t\t\t\t纯化方法\t\t\taffinity purified by Protein A\t\t\t\t\t纯化方法纯化方法\t\t\taffinity purified by Protein Aaffinity purified by Protein A\t\t\t\t\t\t\t储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t储\xa0存\xa0液储\xa0存\xa0液\t\t\t0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\t\t\t\t\t\t\t保存条件\t\t\tStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\t\t\t\t\t保存条件保存条件\t\t\tStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.\t\t\t\t\t\t\tPubMed\t\t\tPubMed\t\t\t\t\tPubMedPubMed\t\t\tPubMedPubMed\t\t\t\t\t\t\t产品介绍\t\t\tbackground:
\t\t\tThis gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
\t\t\t
\t\t\tFunction:
\t\t\tGalactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
\t\t\t
\t\t\tSubunit:
\t\t\tProbably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.
\t\t\t
\t\t\tSubcellular Location:
\t\t\tCytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
\t\t\t
\t\t\tTissue Specificity:
\t\t\tA major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
\t\t\t
\t\t\tSimilarity:
\t\t\tContains 1 galectin domain.
\t\t\t
\t\t\tSWISS:
\t\t\tP17931
\t\t\t
\t\t\tGene ID:
\t\t\t3958
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 3958\xa0Human

\t\t\t

Entrez Gene: 16854\xa0Mouse

\t\t\t

Entrez Gene: 83781\xa0Rat

\t\t\t

Omim: 153619\xa0Human

\t\t\t

SwissProt: P17931\xa0Human

\t\t\t

SwissProt: P16110\xa0Mouse

\t\t\t

SwissProt: P08699\xa0Rat

\t\t\t

Unigene: 531081\xa0Human

\t\t\t

Unigene: 248615\xa0Mouse

\t\t\t

Unigene: 764\xa0Rat

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t
\t\t\tGalectin-3是Galectin（半乳凝素）家族的一员，能识别糖蛋白和糖脂的特异性低聚糖结构，参与多种生理和病理过程，包括细胞生长和凋亡、细胞黏附、新生血管形成和肿瘤浸润与转移等。Galectin-3在肿瘤的发生、发展及转移中起重要作用。
\t\t\tGalectin-3在某些肿瘤组织中高表达，其在不同类型肿瘤，如结直肠癌、胃癌、胰腺癌、甲状腺癌及肺癌等患者中的高表达水平，与低生存、肿瘤复发、预后差及对化疗药物敏感性降低相关对于某些肿瘤，Galectin-3有可能成为一个有价值的诊断标志和治疗靶点。\t\t\t\t\t产品介绍产品介绍\t\t\tbackground:
\t\t\tThis gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
\t\t\t
\t\t\tFunction:
\t\t\tGalactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
\t\t\t
\t\t\tSubunit:
\t\t\tProbably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.
\t\t\t
\t\t\tSubcellular Location:
\t\t\tCytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
\t\t\t
\t\t\tTissue Specificity:
\t\t\tA major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
\t\t\t
\t\t\tSimilarity:
\t\t\tContains 1 galectin domain.
\t\t\t
\t\t\tSWISS:
\t\t\tP17931
\t\t\t
\t\t\tGene ID:
\t\t\t3958
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 3958\xa0Human

\t\t\t

Entrez Gene: 16854\xa0Mouse

\t\t\t

Entrez Gene: 83781\xa0Rat

\t\t\t

Omim: 153619\xa0Human

\t\t\t

SwissProt: P17931\xa0Human

\t\t\t

SwissProt: P16110\xa0Mouse

\t\t\t

SwissProt: P08699\xa0Rat

\t\t\t

Unigene: 531081\xa0Human

\t\t\t

Unigene: 248615\xa0Mouse

\t\t\t

Unigene: 764\xa0Rat

\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t
\t\t\tGalectin-3是Galectin（半乳凝素）家族的一员，能识别糖蛋白和糖脂的特异性低聚糖结构，参与多种生理和病理过程，包括细胞生长和凋亡、细胞黏附、新生血管形成和肿瘤浸润与转移等。Galectin-3在肿瘤的发生、发展及转移中起重要作用。
\t\t\tGalectin-3在某些肿瘤组织中高表达，其在不同类型肿瘤，如结直肠癌、胃癌、胰腺癌、甲状腺癌及肺癌等患者中的高表达水平，与低生存、肿瘤复发、预后差及对化疗药物敏感性降低相关对于某些肿瘤，Galectin-3有可能成为一个有价值的诊断标志和治疗靶点。background:
\t\t\tThis gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
\t\t\t
\t\t\tFunction:
\t\t\tGalactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
\t\t\t
\t\t\tSubunit:
\t\t\tProbably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.
\t\t\t
\t\t\tSubcellular Location:
\t\t\tCytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
\t\t\t
\t\t\tTissue Specificity:
\t\t\tA major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
\t\t\t
\t\t\tSimilarity:
\t\t\tContains 1 galectin domain.
\t\t\t
\t\t\tSWISS:
\t\t\tP17931
\t\t\t
\t\t\tGene ID:
\t\t\t3958
\t\t\t
\t\t\tDatabase links:\t\t\t

Entrez Gene: 3958\xa0Human

Entrez Gene: 3958\xa0Human\t\t\t

Entrez Gene: 16854\xa0Mouse

Entrez Gene: 16854\xa0Mouse\t\t\t

Entrez Gene: 83781\xa0Rat

Entrez Gene: 83781\xa0Rat\t\t\t

Omim: 153619\xa0Human

Omim: 153619\xa0Human\t\t\t

SwissProt: P17931\xa0Human

SwissProt: P17931\xa0Human\t\t\t

SwissProt: P16110\xa0Mouse

SwissProt: P16110\xa0Mouse\t\t\t

SwissProt: P08699\xa0Rat

SwissProt: P08699\xa0Rat\t\t\t

Unigene: 531081\xa0Human

Unigene: 531081\xa0Human\t\t\t

Unigene: 248615\xa0Mouse

Unigene: 248615\xa0Mouse\t\t\t

Unigene: 764\xa0Rat

Unigene: 764\xa0Rat\t\t\t
\t\t\t
\t\t\tImportant Note:
\t\t\tThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\xa0
\t\t\t
\t\t\tGalectin-3是Galectin（半乳凝素）家族的一员，能识别糖蛋白和糖脂的特异性低聚糖结构，参与多种生理和病理过程，包括细胞生长和凋亡、细胞黏附、新生血管形成和肿瘤浸润与转移等。Galectin-3在肿瘤的发生、发展及转移中起重要作用。
\t\t\tGalectin-3在某些肿瘤组织中高表达，其在不同类型肿瘤，如结直肠癌、胃癌、胰腺癌、甲状腺癌及肺癌等患者中的高表达水平，与低生存、肿瘤复发、预后差及对化疗药物敏感性降低相关对于某些肿瘤，Galectin-3有可能成为一个有价值的诊断标志和治疗靶点。\t\t\t\t\t\t\t产品图片\t\t\t
\t\t\tSample:MCF-7(human) Cell Lysate at 40 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 27 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela(Human) Cell Lysate at 30 ug
\t\t\tHela KO Galectin3 (Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti- Galectin3 (bs-20699R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela Cell (Human) Lysate at 40 ug
\t\t\tMCF-7 Cell (Human) Lysate at 40 ug
\t\t\tPrimary: Anti- Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample: MCF-7(Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R-HRP) at 1/1000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD\t\t\t\t\t产品图片产品图片\t\t\t
\t\t\tSample:MCF-7(human) Cell Lysate at 40 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 27 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela(Human) Cell Lysate at 30 ug
\t\t\tHela KO Galectin3 (Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti- Galectin3 (bs-20699R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela Cell (Human) Lysate at 40 ug
\t\t\tMCF-7 Cell (Human) Lysate at 40 ug
\t\t\tPrimary: Anti- Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample: MCF-7(Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R-HRP) at 1/1000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\tSample:MCF-7(human) Cell Lysate at 40 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 27 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela(Human) Cell Lysate at 30 ug
\t\t\tHela KO Galectin3 (Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti- Galectin3 (bs-20699R) at 1/1000 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample:\xa0
\t\t\tHela Cell (Human) Lysate at 40 ug
\t\t\tMCF-7 Cell (Human) Lysate at 40 ug
\t\t\tPrimary: Anti- Galectin 3 (bs-20699R) at 1/300 dilution
\t\t\tSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD
\t\t\t
\t\t\t
\t\t\tSample: MCF-7(Human) Cell Lysate at 30 ug
\t\t\tPrimary: Anti-Galectin 3 (bs-20699R-HRP) at 1/1000 dilution
\t\t\tPredicted band size: 29 kD
\t\t\tObserved band size: 29 kD