| 英文名称 | IL12 |
| 中文名称 | 白介素12抗体 |
| 别 名 | IL12; IL-12; CLMF p35; CLMF1; CTL maturation factor (TcMF); Cytotoxic lymphocyte maturation factor 1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL 12 subunit p35; IL12A; Interleukin 12 alpha chain; Interleukin 12 p35; Interleukin 12A; Natural killer cell stimulatory factor 1; CLMF; CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12A; IL12 subunit p35; IL12A; IL12A_HUMAN; Interleukin 12 p35; Interleukin 12A; Interleukin-12 subunit alpha; NFSK; NK cell stimulatory factor chain 1; NKSF1. NK cell stimulatory factor chain 1; NKSF1; p35; IL12A_MOUSE. |
| 英文名称 | IL12 |
| 中文名称 | 白介素12抗体 |
| 别 名 | IL12; IL-12; CLMF p35; CLMF1; CTL maturation factor (TcMF); Cytotoxic lymphocyte maturation factor 1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL 12 subunit p35; IL12A; Interleukin 12 alpha chain; Interleukin 12 p35; Interleukin 12A; Natural killer cell stimulatory factor 1; CLMF; CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12A; IL12 subunit p35; IL12A; IL12A_HUMAN; Interleukin 12 p35; Interleukin 12A; Interleukin-12 subunit alpha; NFSK; NK cell stimulatory factor chain 1; NKSF1. NK cell stimulatory factor chain 1; NKSF1; p35; IL12A_MOUSE. |
| 英文名称 | IL12 |
英文名称 | 英文名称
IL12 | IL12
| 中文名称 | 白介素12抗体 |
中文名称 | 中文名称
白介素12抗体 | 白介素12抗体
| 别 名 | IL12; IL-12; CLMF p35; CLMF1; CTL maturation factor (TcMF); Cytotoxic lymphocyte maturation factor 1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL 12 subunit p35; IL12A; Interleukin 12 alpha chain; Interleukin 12 p35; Interleukin 12A; Natural killer cell stimulatory factor 1; CLMF; CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12A; IL12 subunit p35; IL12A; IL12A_HUMAN; Interleukin 12 p35; Interleukin 12A; Interleukin-12 subunit alpha; NFSK; NK cell stimulatory factor chain 1; NKSF1. NK cell stimulatory factor chain 1; NKSF1; p35; IL12A_MOUSE. |
别 名 | 别 名
IL12; IL-12; CLMF p35; CLMF1; CTL maturation factor (TcMF); Cytotoxic lymphocyte maturation factor 1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL 12 subunit p35; IL12A; Interleukin 12 alpha chain; Interleukin 12 p35; Interleukin 12A; Natural killer cell stimulatory factor 1; CLMF; CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12A; IL12 subunit p35; IL12A; IL12A_HUMAN; Interleukin 12 p35; Interleukin 12A; Interleukin-12 subunit alpha; NFSK; NK cell stimulatory factor chain 1; NKSF1. NK cell stimulatory factor chain 1; NKSF1; p35; IL12A_MOUSE. | IL12; IL-12; CLMF p35; CLMF1; CTL maturation factor (TcMF); Cytotoxic lymphocyte maturation factor 1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL 12 subunit p35; IL12A; Interleukin 12 alpha chain; Interleukin 12 p35; Interleukin 12A; Natural killer cell stimulatory factor 1; CLMF; CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12A; IL12 subunit p35; IL12A; IL12A_HUMAN; Interleukin 12 p35; Interleukin 12A; Interleukin-12 subunit alpha; NFSK; NK cell stimulatory factor chain 1; NKSF1. NK cell stimulatory factor chain 1; NKSF1; p35; IL12A_MOUSE.
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 细胞定位 | 细胞膜 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse IL-12:51-150/215 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Function:
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Subunit:
Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-6 superfamily.
SWISS:
P43431
Gene ID:
16159
Database links:Entrez Gene: 3592 Human Entrez Gene: 16159 Mouse Entrez Gene: 84405 Rat Omim: 161560 Human SwissProt: P29459 Human SwissProt: P43431 Mouse SwissProt: Q9R103 Rat Unigene: 673 Human Unigene: 103783 Mouse Unigene: 207199 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IL-12是新近发现的细胞因子，具有多种生物学活性，尤其是在抗肿瘤免疫和抗病毒免疫中有重要的作用。 |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 细胞定位 | 细胞膜 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse IL-12:51-150/215 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Function:
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Subunit:
Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-6 superfamily.
SWISS:
P43431
Gene ID:
16159
Database links:Entrez Gene: 3592 Human Entrez Gene: 16159 Mouse Entrez Gene: 84405 Rat Omim: 161560 Human SwissProt: P29459 Human SwissProt: P43431 Mouse SwissProt: Q9R103 Rat Unigene: 673 Human Unigene: 103783 Mouse Unigene: 207199 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IL-12是新近发现的细胞因子，具有多种生物学活性，尤其是在抗肿瘤免疫和抗病毒免疫中有重要的作用。 |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
研究领域 | 研究领域
肿瘤 细胞生物 免疫学 | 肿瘤 细胞生物 免疫学
| 抗体来源 | Rabbit |
抗体来源 | 抗体来源
Rabbit | Rabbit
| 克隆类型 | Polyclonal |
克隆类型 | 克隆类型
Polyclonal | Polyclonal
| 交叉反应 | Mouse, Rat, |
交叉反应 | 交叉反应
Mouse, Rat, | Mouse, Rat,
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
产品应用 | 产品应用
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
| 分 子 量 | 22kDa |
分 子 量 | 分 子 量
22kDa | 22kDa
| 细胞定位 | 细胞膜 分泌型蛋白 |
细胞定位 | 细胞定位
细胞膜 分泌型蛋白 | 细胞膜 分泌型蛋白
| 性 状 | Liquid |
性 状 | 性 状
Liquid | Liquid
| 浓 度 | 1mg/ml |
浓 度 | 浓 度
1mg/ml | 1mg/ml
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse IL-12:51-150/215 |
免 疫 原 | 免 疫 原
KLH conjugated synthetic peptide derived from mouse IL-12:51-150/215 | KLH conjugated synthetic peptide derived from mouse IL-12:51-150/215
| 亚 型 | IgG |
亚 型 | 亚 型
IgG | IgG
| 纯化方法 | affinity purified by Protein A |
纯化方法 | 纯化方法
affinity purified by Protein A | affinity purified by Protein A
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
储 存 液 | 储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
保存条件 | 保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
| PubMed | PubMed |
PubMed | PubMed
PubMed | PubMedPubMed
| 产品介绍 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Function:
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Subunit:
Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-6 superfamily.
SWISS:
P43431
Gene ID:
16159
Database links:Entrez Gene: 3592 Human Entrez Gene: 16159 Mouse Entrez Gene: 84405 Rat Omim: 161560 Human SwissProt: P29459 Human SwissProt: P43431 Mouse SwissProt: Q9R103 Rat Unigene: 673 Human Unigene: 103783 Mouse Unigene: 207199 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IL-12是新近发现的细胞因子，具有多种生物学活性，尤其是在抗肿瘤免疫和抗病毒免疫中有重要的作用。 |
产品介绍 | 产品介绍
IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Function:
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Subunit:
Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-6 superfamily.
SWISS:
P43431
Gene ID:
16159
Database links:Entrez Gene: 3592 Human Entrez Gene: 16159 Mouse Entrez Gene: 84405 Rat Omim: 161560 Human SwissProt: P29459 Human SwissProt: P43431 Mouse SwissProt: Q9R103 Rat Unigene: 673 Human Unigene: 103783 Mouse Unigene: 207199 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IL-12是新近发现的细胞因子，具有多种生物学活性，尤其是在抗肿瘤免疫和抗病毒免疫中有重要的作用。 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Function:
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Subunit:
Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-6 superfamily.
SWISS:
P43431
Gene ID:
16159
Database links:
Entrez Gene: 3592 Human
Entrez Gene: 3592Entrez Gene: 3592 Human
Entrez Gene: 16159 Mouse
Entrez Gene: 16159Entrez Gene: 16159 Mouse
Entrez Gene: 84405 Rat
Entrez Gene: 84405Entrez Gene: 84405 Rat
Omim: 161560 Human
Omim: 161560Omim: 161560 Human
SwissProt: P29459 Human
SwissProt: P29459SwissProt: P29459 Human
SwissProt: P43431 Mouse
SwissProt: P43431SwissProt: P43431 Mouse
SwissProt: Q9R103 Rat
SwissProt: Q9R103SwissProt: Q9R103 Rat
Unigene: 673 Human
Unigene: 673Unigene: 673 Human
Unigene: 103783 Mouse
Unigene: 103783Unigene: 103783 Mouse
Unigene: 207199 Rat
Unigene: 207199Unigene: 207199 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IL-12是新近发现的细胞因子，具有多种生物学活性，尤其是在抗肿瘤免疫和抗病毒免疫中有重要的作用。
