英文名称	P2Y8
中文名称	G蛋白偶联嘌呤受体p2y8抗体
别 名	P2RY8; P2RY8_HUMAN; P2Y purinoceptor 8; P2Y8; Purinergic receptor P2Y G protein coupled 8.
研究领域	神经生物学 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	41kDa
细胞定位	细胞膜
性 状	Liquid
浓 度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human P2Y8:131-230/359 <Extracellular>
亚 型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G-protein coupled receptors translate extracellular signals into intracellular signals (G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. P2RY8 (purinergic receptor P2Y, G-protein coupled, 8), also known as P2Y8, is a 359 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein-coupled receptor family. Expressed at low levels in lung, heart and kidney, P2RY8 may function as a receptor for purines that are coupled to G proteins and may also play a role in mental retardation. Function: Probable receptor for purines coupled to G-proteins. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q86VZ1 Gene ID: 286530 Database links: Entrez Gene: 286530 Human Omim: 300525 Human SwissProt: Q86VZ1 Human Unigene: 111377 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

英文名称P2Y8中文名称G蛋白偶联嘌呤受体p2y8抗体别 名P2RY8; P2RY8_HUMAN; P2Y purinoceptor 8; P2Y8; Purinergic receptor P2Y G protein coupled 8.研究领域神经生物学 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号抗体来源Rabbit克隆类型Polyclonal交叉反应Human,产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.分 子 量41kDa细胞定位细胞膜性 状Liquid浓 度1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human P2Y8:131-230/359 <Extracellular>亚 型IgG纯化方法affinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMedPubMed产品介绍G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G-protein coupled receptors translate extracellular signals into intracellular signals (G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. P2RY8 (purinergic receptor P2Y, G-protein coupled, 8), also known as P2Y8, is a 359 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein-coupled receptor family. Expressed at low levels in lung, heart and kidney, P2RY8 may function as a receptor for purines that are coupled to G proteins and may also play a role in mental retardation.

Function:
Probable receptor for purines coupled to G-proteins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q86VZ1

Gene ID:
286530

Database links:

Entrez Gene: 286530 Human

Omim: 300525 Human

SwissProt: Q86VZ1 Human

Unigene: 111377 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.英文名称P2Y8英文名称英文名称P2Y8P2Y8中文名称G蛋白偶联嘌呤受体p2y8抗体中文名称中文名称G蛋白偶联嘌呤受体p2y8抗体G蛋白偶联嘌呤受体p2y8抗体别 名P2RY8; P2RY8_HUMAN; P2Y purinoceptor 8; P2Y8; Purinergic receptor P2Y G protein coupled 8.别 名别 名P2RY8; P2RY8_HUMAN; P2Y purinoceptor 8; P2Y8; Purinergic receptor P2Y G protein coupled 8.P2RY8; P2RY8_HUMAN; P2Y purinoceptor 8; P2Y8; Purinergic receptor P2Y G protein coupled 8.研究领域神经生物学 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号研究领域研究领域神经生物学 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号神经生物学 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号抗体来源Rabbit抗体来源抗体来源RabbitRabbit克隆类型Polyclonal克隆类型克隆类型PolyclonalPolyclonal交叉反应Human,交叉反应交叉反应Human,Human,产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.产品应用产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.分 子 量41kDa分 子 量分 子 量41kDa41kDa细胞定位细胞膜细胞定位细胞定位细胞膜细胞膜性 状Liquid性 状性 状LiquidLiquid浓 度1mg/ml浓 度浓 度1mg/ml1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human P2Y8:131-230/359 <Extracellular>免 疫 原免 疫 原KLH conjugated synthetic peptide derived from human P2Y8:131-230/359 <Extracellular>KLH conjugated synthetic peptide derived from human P2Y8:131-230/359 亚 型IgG亚 型亚 型IgGIgG纯化方法affinity purified by Protein A纯化方法纯化方法affinity purified by Protein Aaffinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.储 存 液储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.保存条件保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMedPubMedPubMedPubMedPubMedPubMedPubMed产品介绍G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G-protein coupled receptors translate extracellular signals into intracellular signals (G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. P2RY8 (purinergic receptor P2Y, G-protein coupled, 8), also known as P2Y8, is a 359 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein-coupled receptor family. Expressed at low levels in lung, heart and kidney, P2RY8 may function as a receptor for purines that are coupled to G proteins and may also play a role in mental retardation.

Function:
Probable receptor for purines coupled to G-proteins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q86VZ1

Gene ID:
286530

Database links:

Entrez Gene: 286530 Human

Omim: 300525 Human

SwissProt: Q86VZ1 Human

Unigene: 111377 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.产品介绍产品介绍G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G-protein coupled receptors translate extracellular signals into intracellular signals (G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. P2RY8 (purinergic receptor P2Y, G-protein coupled, 8), also known as P2Y8, is a 359 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein-coupled receptor family. Expressed at low levels in lung, heart and kidney, P2RY8 may function as a receptor for purines that are coupled to G proteins and may also play a role in mental retardation.

Function:
Probable receptor for purines coupled to G-proteins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q86VZ1

Gene ID:
286530

Database links:

Entrez Gene: 286530 Human

Omim: 300525 Human

SwissProt: Q86VZ1 Human

Unigene: 111377 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G-protein coupled receptors translate extracellular signals into intracellular signals (G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. P2RY8 (purinergic receptor P2Y, G-protein coupled, 8), also known as P2Y8, is a 359 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein-coupled receptor family. Expressed at low levels in lung, heart and kidney, P2RY8 may function as a receptor for purines that are coupled to G proteins and may also play a role in mental retardation.

Function:
Probable receptor for purines coupled to G-proteins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q86VZ1

Gene ID:
286530

Database links:

Entrez Gene: 286530 Human

Entrez Gene: 286530Entrez Gene: 286530 Human

Omim: 300525 Human

Omim: 300525Omim: 300525 Human

SwissProt: Q86VZ1 Human

SwissProt: Q86VZ1SwissProt: Q86VZ1 Human

Unigene: 111377 Human

Unigene: 111377Unigene: 111377 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.