本公司提供科研MAGE-1黑色素瘤相关抗原抗体MAGE-1黑色素瘤相关抗原抗体，抗体质量可靠，订购MAGE-1黑色素瘤相关抗原抗体MAGE-1黑色素瘤相关抗原抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：黑色素瘤相关抗原抗体黑色素瘤相关抗原抗体
英文名称：Anti-MAGE-1Anti-MAGE-1
货号：bs-0817R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The MAGE 1 gene is a member of the melanoma antigen encoding gene family. These genes encode for HLA-restricted tumor associated rejection antigens recognized by cytotoxic T lymphocytes. Some of these target antigens may be potentially useful for cancer specific immunotherapy. The expression of MAGE genes has been reported not only in melanoma but also in various other malignant tumors such as hepatocellular carcinoma and germ cell tumors.Subcellular Location : CytoplasmicMage-1表达于正常的黑素细胞和大多数原发及转移的黑色素瘤中，故称：黑色素瘤相关抗原。MAGE-1是重要的肿瘤特异性抗原-MAGE家族成员,近年被认为是一种辨别黑色素病变的有效抗原。主要用于恶性肿瘤方面的研究。MAGE-1基因属于黑色素瘤抗原编码基因家族，其编码产物表达于各种组织类型的肿瘤中。包括黑色素瘤、神经胶质脑肿瘤、成神经细胞瘤、肾细胞癌等，但正常组织表达量较少货没有。产品图片Tissue/cell: rat lung tissue（Melanoma）; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-MAGE-1 Polyclonal Antibody, Unconjugated(bs-0817R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining