本公司提供科研RASSF6RAS家族关联结构域蛋白6抗体RASSF6RAS家族关联结构域蛋白6抗体，抗体质量可靠，订购RASSF6RAS家族关联结构域蛋白6抗体RASSF6RAS家族关联结构域蛋白6抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：RAS家族关联结构域蛋白6抗体RAS家族关联结构域蛋白6抗体
英文名称：Anti-RASSF6Anti-RASSF6
货号：bs-5955R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 41kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：RASSF6 contains 1 Ras-associating domain and 1 SARAH domain. It may act as a Ras effector protein. There are four isoforms. Function : Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity).Subunit : Interacts with MOAP1 (By similarity). Interaction with activated KRAS is still a matter of debate: interaction has been shown in the mouse (PubMed:17404571), but not in human (PubMed:17367779). Lack of interaction with MRAS, NRAS nor RRAS2 has also been reported (PubMed:17367779).Tissue Specificity : Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart.Similarity : Contains 1 Ras-associating domain.Contains 1 SARAH domain.