本公司提供科研UBE2J2泛素蛋白连接酶J2抗体UBE2J2泛素蛋白连接酶J2抗体，抗体质量可靠，订购UBE2J2泛素蛋白连接酶J2抗体UBE2J2泛素蛋白连接酶J2抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：泛素蛋白连接酶J2抗体泛素蛋白连接酶J2抗体
英文名称：Anti-UBE2J2Anti-UBE2J2
货号：bs-8381R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 29kDa
纯化方法：affinity purified by Protein A
交叉反应：Hu, mo, rat, horse, chicken, cow, dog
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.