商品分类：多克隆抗体

靶点/蛋白：ABD10963 detects cyclin E, a nuclear protein which is the regulatory subunit of cyclin dependent kinase 2 (Cdk2), and controls S phase entry in cells. Cyclin E follows a cyclic pattern of expression during the cell cycle, with highest expression at the G1-S boundary. Although cyclin E has an important physiological role in normal cell division, recent reports suggest this function is redundant, and its key functions occur as cells exit quiescence, and in endoreduplication. Cyclin E is tightly regulated during normal cell cycles, but is often deregulated in carcinomas, lymphoma, and leukaemia.

来源：Rabbit

参考文献：1. Hwang, H.C. and Clurman, B.E. (2005) Cyclin E in normal and neoplastic cell cycles. Oncogene. 24: 2776-2786.2. Zhang H. (2007) Life without kinase: cyclin E promotes DNA replication licensing and beyond. Mol. Cell. 25: 175-176.

特异性：Human

别名：G1/S-specific cyclin-E1, CCNE1, CCNE

简单描述：Rabbit Polyclonal Anti-Cyclin E Antibody (Serum). Validated for use in WB, E, IP.

生物商城：http://www.annoron.comhttp://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层