LXR beta肝脏X受体β抗体LXR beta肝脏X受体β抗体LXR beta肝脏X受体β抗体
| 英文名称 | LXR beta |
| 中文名称 | 肝脏X受体β抗体 |
| 别 名 | Liver X nuclear receptor beta; Liver X receptor beta; Liver X receptor beta; LX receptor beta; LXR b; LXR beta; LXRB; NER 1; NER; NER I; NER1; NERI; NR1H 2; NR1H; NR1H2; NR1H2 protein; NR1H2_HUMAN; Nuclear orphan receptor LXR beta; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; OR-1; Oxysterols receptor LXR beta; Oxysterols receptor LXR-beta; RIP 15; RIP15; steroid hormone nuclear receptor NER; Ubiquitously expressed nuclear receptor; Ubiquitously-expressed nuclear receptor; UENR; UNR. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 细胞膜受体 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LXR beta:361-460/460 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background:
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Function:
Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Subunit:
Forms a heterodimer with RXR.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the nuclear hormone receptor family.
NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
SWISS:
P55055
Gene ID:
7376
Database links:Entrez Gene: 7376 Human Entrez Gene: 58851 Rat Omim: 600380 Human SwissProt: P55055 Human SwissProt: Q62755 Rat Unigene: 432976 Human Unigene: 786 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
| 产品图片 | 
Sample: small intestine (Mouse) Lysate at 40 ug
Primary: Anti-LXR beta(bs-18450R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD |
| 英文名称 | LXR beta |
| 中文名称 | 肝脏X受体β抗体 |
| 别 名 | Liver X nuclear receptor beta; Liver X receptor beta; Liver X receptor beta; LX receptor beta; LXR b; LXR beta; LXRB; NER 1; NER; NER I; NER1; NERI; NR1H 2; NR1H; NR1H2; NR1H2 protein; NR1H2_HUMAN; Nuclear orphan receptor LXR beta; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; OR-1; Oxysterols receptor LXR beta; Oxysterols receptor LXR-beta; RIP 15; RIP15; steroid hormone nuclear receptor NER; Ubiquitously expressed nuclear receptor; Ubiquitously-expressed nuclear receptor; UENR; UNR. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 细胞膜受体 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LXR beta:361-460/460 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background:
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Function:
Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Subunit:
Forms a heterodimer with RXR.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the nuclear hormone receptor family.
NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
SWISS:
P55055
Gene ID:
7376
Database links:Entrez Gene: 7376 Human Entrez Gene: 58851 Rat Omim: 600380 Human SwissProt: P55055 Human SwissProt: Q62755 Rat Unigene: 432976 Human Unigene: 786 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
| 产品图片 |
Sample: small intestine (Mouse) Lysate at 40 ug
Primary: Anti-LXR beta(bs-18450R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD |
| 英文名称 | LXR beta |
英文名称 | 英文名称
LXR beta | LXR beta
| 中文名称 | 肝脏X受体β抗体 |
中文名称 | 中文名称
肝脏X受体β抗体 | 肝脏X受体β抗体
| 别 名 | Liver X nuclear receptor beta; Liver X receptor beta; Liver X receptor beta; LX receptor beta; LXR b; LXR beta; LXRB; NER 1; NER; NER I; NER1; NERI; NR1H 2; NR1H; NR1H2; NR1H2 protein; NR1H2_HUMAN; Nuclear orphan receptor LXR beta; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; OR-1; Oxysterols receptor LXR beta; Oxysterols receptor LXR-beta; RIP 15; RIP15; steroid hormone nuclear receptor NER; Ubiquitously expressed nuclear receptor; Ubiquitously-expressed nuclear receptor; UENR; UNR. |
别 名 | 别 名
Liver X nuclear receptor beta; Liver X receptor beta; Liver X receptor beta; LX receptor beta; LXR b; LXR beta; LXRB; NER 1; NER; NER I; NER1; NERI; NR1H 2; NR1H; NR1H2; NR1H2 protein; NR1H2_HUMAN; Nuclear orphan receptor LXR beta; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; OR-1; Oxysterols receptor LXR beta; Oxysterols receptor LXR-beta; RIP 15; RIP15; steroid hormone nuclear receptor NER; Ubiquitously expressed nuclear receptor; Ubiquitously-expressed nuclear receptor; UENR; UNR. | Liver X nuclear receptor beta; Liver X receptor beta; Liver X receptor beta; LX receptor beta; LXR b; LXR beta; LXRB; NER 1; NER; NER I; NER1; NERI; NR1H 2; NR1H; NR1H2; NR1H2 protein; NR1H2_HUMAN; Nuclear orphan receptor LXR beta; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; OR-1; Oxysterols receptor LXR beta; Oxysterols receptor LXR-beta; RIP 15; RIP15; steroid hormone nuclear receptor NER; Ubiquitously expressed nuclear receptor; Ubiquitously-expressed nuclear receptor; UENR; UNR.
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
规格价格 | 规格价格
100ul/1380元 购买 200ul/2200元 购买 大包装/询价 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价
| 说 明 书 | 100ul 200ul |
说 明 书 | 说 明 书
100ul 200ul | 100ul 200ul
| 研究领域 | 肿瘤 细胞生物 细胞膜受体 表观遗传学 |
研究领域 | 研究领域
肿瘤 细胞生物 细胞膜受体 表观遗传学 | 肿瘤 细胞生物 细胞膜受体 表观遗传学
| 抗体来源 | Rabbit |
抗体来源 | 抗体来源
Rabbit | Rabbit
| 克隆类型 | Polyclonal |
克隆类型 | 克隆类型
Polyclonal | Polyclonal
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
交叉反应 | 交叉反应
Human, Mouse, Rat, Dog, Pig, Cow, Sheep, | Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
产品应用 | 产品应用
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
| 分 子 量 | 51kDa |
分 子 量 | 分 子 量
51kDa | 51kDa
| 细胞定位 | 细胞核 |
细胞定位 | 细胞定位
细胞核 | 细胞核
| 性 状 | Lyophilized or Liquid |
性 状 | 性 状
Lyophilized or Liquid | Lyophilized or Liquid
| 浓 度 | 1mg/ml |
浓 度 | 浓 度
1mg/ml | 1mg/ml
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LXR beta:361-460/460 |
免 疫 原 | 免 疫 原
KLH conjugated synthetic peptide derived from human LXR beta:361-460/460 | KLH conjugated synthetic peptide derived from human LXR beta:361-460/460
| 亚 型 | IgG |
亚 型 | 亚 型
IgG | IgG
| 纯化方法 | affinity purified by Protein A |
纯化方法 | 纯化方法
affinity purified by Protein A | affinity purified by Protein A
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
储 存 液 | 储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
保存条件 | 保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
| PubMed | PubMed |
PubMed | PubMed
PubMed | PubMed
| 产品介绍 | background:
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Function:
Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Subunit:
Forms a heterodimer with RXR.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the nuclear hormone receptor family.
NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
SWISS:
P55055
Gene ID:
7376
Database links:Entrez Gene: 7376 Human Entrez Gene: 58851 Rat Omim: 600380 Human SwissProt: P55055 Human SwissProt: Q62755 Rat Unigene: 432976 Human Unigene: 786 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
产品介绍 | 产品介绍
background:
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Function:
Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Subunit:
Forms a heterodimer with RXR.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the nuclear hormone receptor family.
NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
SWISS:
P55055
Gene ID:
7376
Database links:Entrez Gene: 7376 Human Entrez Gene: 58851 Rat Omim: 600380 Human SwissProt: P55055 Human SwissProt: Q62755 Rat Unigene: 432976 Human Unigene: 786 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
| background:
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Function:
Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Subunit:
Forms a heterodimer with RXR.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the nuclear hormone receptor family.
NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
SWISS:
P55055
Gene ID:
7376
Database links:
Entrez Gene: 7376 Human
Entrez Gene: 7376 Human
Entrez Gene: 58851 Rat
Entrez Gene: 58851 Rat
Omim: 600380 Human
Omim: 600380 Human
SwissProt: P55055 Human
SwissProt: P55055 Human
SwissProt: Q62755 Rat
SwissProt: Q62755 Rat
Unigene: 432976 Human
Unigene: 432976 Human
Unigene: 786 Rat
Unigene: 786 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
| 产品图片 |
Sample: small intestine (Mouse) Lysate at 40 ug
Primary: Anti-LXR beta(bs-18450R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD |
产品图片 | 产品图片
Sample: small intestine (Mouse) Lysate at 40 ug
Primary: Anti-LXR beta(bs-18450R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD | Sample: small intestine (Mouse) Lysate at 40 ug
Primary: Anti-LXR beta(bs-18450R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 51 kD
