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ID：T3066
ID：T3066PURITY：0.9975
PURITY：0.9975Formula：C17H18N6
Formula：C17H18N6MolWt：360.36
MolWt：360.36Appearance：白色粉末
Appearance：白色粉末Solubility：G4DMSO 61 mg/mL;Water <1 mg/mL
Solubility：G4DMSO 61 mg/mL;Water <1 mg/mLBioactivity：Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.
Bioactivity：Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.Status：FDA
Status：FDAPathways：JAK/STAT Signaling
Pathways：JAK/STAT SignalingTarget：JAK inhibitor
Target：JAK inhibitorReceptor：JAK1, JAK2
Receptor：JAK1, JAK2
