货号 PAab03833
货号 PAab03833蛋白别名 CD340 antibody, ERBB2 antibody, HER 2 antibody, HER 2/neu antibody, HER2 antibody, MLN 19 antibody, MLN19 antibody, NEU antibody, NGL antibody, p185 antibody, p185erbB2 antibody, Proto oncogene c ErbB 2 antibody, Proto oncogene Neu antibody, TKR1
蛋白别名 CD340 antibody, ERBB2 antibody, HER 2 antibody, HER 2/neu antibody, HER2 antibody, MLN 19 antibody, MLN19 antibody, NEU antibody, NGL antibody, p185 antibody, p185erbB2 antibody, Proto oncogene c ErbB 2 antibody, Proto oncogene Neu antibody, TKR1蛋白别名 CD340 antibody, ERBB2 antibody, HER 2 antibody, HER 2/neu antibody, HER2 antibody, MLN 19 antibody, MLN19 antibody, NEU antibody, NGL antibody, p185 antibody, p185erbB2 antibody, Proto oncogene c ErbB 2 antibody, Proto oncogene Neu antibody, TKR1蛋白介绍
蛋白介绍蛋白介绍HER2, also known as ErbB2 and Neu, is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase- mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of HER2 have been reported in numerous cancers, including breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast cancer and other carcinomas. This antibody raised against a synthesized peptide corresponding to 1237-1255aa of human HER2 recognizes the 185-kDa full-length glycosylated form and other lower molecular-mass forms of HER2, including the truncated form.
HER2, also known as ErbB2 and Neu, is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase- mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of HER2 have been reported in numerous cancers, including breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast cancer and other carcinomas. This antibody raised against a synthesized peptide corresponding to 1237-1255aa of human HER2 recognizes the 185-kDa full-length glycosylated form and other lower molecular-mass forms of HER2, including the truncated form.HER2, also known as ErbB2 and Neu, is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase- mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of HER2 have been reported in numerous cancers, including breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast cancer and other carcinomas. This antibody raised against a synthesized peptide corresponding to 1237-1255aa of human HER2 recognizes the 185-kDa full-length glycosylated form and other lower molecular-mass forms of HER2, including the truncated form.产品描述
产品描述产品描述建议稀释比例
建议稀释比例建议稀释比例WB : 1:1000-1:10000IP : 1:200-1:2000IHC : 1:50-1:200
WB : 1:1000-1:10000IP : 1:200-1:2000IHC : 1:50-1:200WB : 1:1000-1:10000IP : 1:200-1:2000IHC : 1:50-1:200IHC
IHCIHCImmunohistochemistry of paraffin-embedded human breast cancer using PAab03833(ERBB2 antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human breast cancer using PAab03833(ERBB2 antibody) at dilution of 1:50Immunohistochemistry of paraffin-embedded human breast cancer using PAab03833(ERBB2 antibody) at dilution of 1:50Western blot
Western blotWestern blotHeLa cells were subjected to SDS PAGE followed by western blot with PAab03833(ERBB2 antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!)
HeLa cells were subjected to SDS PAGE followed by western blot with PAab03833(ERBB2 antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!)HeLa cells were subjected to SDS PAGE followed by western blot with PAab03833(ERBB2 antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断本抗体仅供体外科研用途，不可用于临床诊断!!)武汉维克赛思科技有限公司
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