phospho-Histone H1(Thr146) Antibody
Cat#：PL0303365
Isotype:Rabbit Polyclonal IgG
Immunogen：PhosphoPeptide derived from human Histone H1.4 around the phosphorylation site of T146.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
Alternate Names：
Histone H1 (phospho T146); p-Histone H1 (phospho T146); phospho-Histone H1.4 (Thr146);HIST1H1E; H1F4; Histone H1.4; Histone H1b; H14_HUMAN; Histone H1s-4; H1 histone family member 4; H1E; Hist1h1e; Histone 1 H1e; Histone cluster 1 H1e; Histone H1; MGC116819.
Specificity Reaction：Hu, Mo, Rat, Pig, Cow, Hor,
Application Notes:WB: 1:100-500 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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