关键词：ILT-3抗体;白细胞免疫球蛋白样受体亚家族B成员4抗体;白细胞免疫球蛋白样受体亚家族B成员4;LILRB4; ILT3; LIR5; Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85 antigen-like family member K; Immunoglobulin-like transcript 3; ILT-3; Leukocyte immunoglobulin-like receptor 5; LIR-5; Monocyte inhibitory receptor HM18;;ABP53583

中文名称：白细胞免疫球蛋白样受体亚家族B成员4多克隆抗体/ILT-3 Polyclonal Antibody

英文名称：ILT-3 Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP53583.pdf

产品描述：兔抗-白细胞免疫球蛋白样受体亚家族B成员4 多克隆抗体

LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B4 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

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