重组恒河猴S100钙结合蛋白B/Rhesus Macaque S100b
Recombinant Rhesus Macaque S100 Calcium Binding Protein B

CATALOGUE NUMBER

PRO-1236

SYNONYMS

Protein S100-B, S100 calcium-binding protein B, S-100 protein subunit beta, S-100 protein beta chain, S100B, NEF, S100, S100beta.

INTRODUCTION

S100b is a member of the S100 family of proteins which are a family of EF-hand calcium binding proteins that exist mostly as dimers of the 20 currently identified individual S100 monomers. The S100B homodimer is expressed in cells of the central nervous system, glial cells and in certain peripheral cells e.g. Schwann cells, melanocytes, adipocytes and chondrocytes. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21; however, S100b is located at 21q22.3. The determination of S100B in serum levels may be used to monitor the extent of brain injury and malignant melanoma. S100b proteins may have a role in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of the S100b gene are implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

DESCRIPTION

S100B Rhesus Macaque Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 91 amino acids and having a molecular mass of 10.7kDa.
The S100B Rhesus Macaque is purified by proprietary chromatographic techniques.

SOURCE

Escherichia Coli.

PHYSICAL APPEARANCE

Sterile Filtered White lyophilized (freeze-dried) powder.

FORMULATION

Lyophilized from a 0.2um filtered concentrated solution in PBS, pH 7.4.

SOLUBILITY

It is recommended to reconstitute the lyophilized S100B in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

STABILITY

Lyophilized S100B Rhesus Macaque although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution S100B Rhesus Macaque should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

PURITY

Greater than 97.0% as determined by SDS-PAGE and HPLC analyses.

AMINO ACID SEQUENCE

SELEKAMVAL IDVFHQYSGR EGDKHKLKKS ELKELINNEL SHFLEEIKEQ EVVDKVMETL DSDGDGECDF QEFMAFVAMV TTACHEFFEH E

USAGE

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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pro-237	重组小鼠S100钙结合蛋白A1	Mouse S100A1	Recombinant Mouse S100 Calcium Binding Protein A1
pro-146	重组人S100钙结合蛋白A2	Human S100A2	Recombinant Human S100 Calcium Binding Protein A2
pro-755	重组人S100钙结合蛋白A3	Human S100A3	Recombinant Human S100 Calcium Binding Protein A3
PRO-1166	重组小鼠S100钙结合蛋白A3	Mouse S100A3	Recombinant Mouse S100 Calcium Binding Protein A3
pro-698	重组人S100钙结合蛋白A4	Human S100A4	Recombinant Human S100 Calcium Binding Protein A4
pro-229	重组小鼠S100钙结合蛋白A4	Mouse S100A4	Recombinant Mouse S100 Calcium Binding Protein A4
pro-147	重组人S100钙结合蛋白A5	Human S100A5	Recombinant Human S100 Calcium Binding Protein A5
PRO-1084	重组小鼠S100钙结合蛋白A5	Mouse S100A5	Recombinant Mouse S100 Calcium Binding Protein A5
pro-148	重组人S100钙结合蛋白A6	Human S100A6	Recombinant Human S100 Calcium Binding Protein A6
pro-409	小鼠S100钙结合蛋白A6	Mouse S100A6	Mouse S100 Calcium Binding Protein A6
pro-240	重组小鼠S100钙结合蛋白A6	Mouse S100A6	Recombinant Mouse S100 Calcium Binding Protein A6
pro-149	重组人S100钙结合蛋白A7	Human S100A7	Recombinant Human S100 Calcium Binding Protein A7
pro-756	重组人S100钙结合蛋白A7A	Human S100A7A	Recombinant Human S100 Calcium Binding Protein A7A
pro-800	重组人S100钙结合蛋白A8	Human S100A8	Recombinant Human S100 Calcium Binding Protein A8
pro-150	重组人S100钙结合蛋白A8	Human S100A8, His	Recombinant Human S100 Calcium Binding Protein A8, His Tag
PRO-2329	重组人S100钙结合蛋白A8	Human S100A8, His-Myc	Recombinant Human S100 Calcium Binding Protein A8, His-Myc Tag
pro-233	重组小鼠S100钙结合蛋白A8	Mouse S100A8	Recombinant Mouse S100 Calcium Binding Protein A8
pro-814	重组人S100钙结合蛋白A9	Human S100A9	Recombinant Human S100 Calcium Binding Protein A9
pro-878	重组小鼠S100钙结合蛋白A9	Mouse S100A9	Recombinant Mouse S100 Calcium Binding Protein A9
pro-384	重组人S100钙结合蛋白A10	Human S100A10	Recombinant Human S100 Calcium Binding Protein A10
PRO-2252	重组小鼠S100钙结合蛋白A10	Mouse S100A10	Recombinant Mouse S100 Calcium Binding Protein A10
pro-385	重组人S100钙结合蛋白A11	Human S100A11	Recombinant Human S100 Calcium Binding Protein A11
pro-152	重组人S100钙结合蛋白A12	Human S100A12	Recombinant Human S100 Calcium Binding Protein A12
pro-153	重组人S100钙结合蛋白A13	Human S100A13	Recombinant Human S100 Calcium Binding Protein A13
pro-154	重组人S100钙结合蛋白A14	Human S100A14	Recombinant Human S100 Calcium Binding Protein A14
PRO-1145	重组小鼠S100钙结合蛋白A15	Mouse S100A15	Recombinant Mouse S100 Calcium Binding Protein A15
pro-155	重组人S100钙结合蛋白A16	Human S100A16	Recombinant Human S100 Calcium Binding Protein A16
PRO-2312	重组人S100钙结合蛋白B	Human S100b	Recombinant Human S100 Calcium Binding Protein B
pro-306	重组人S100钙结合蛋白B	Human S100b, His	Recombinant Human S100 Calcium Binding Protein B, His
PRO-2370	重组小鼠S100钙结合蛋白B	Mouse S100b	Recombinant Mouse S100 Calcium Binding Protein B
pro-853	重组小鼠S100钙结合蛋白B	Mouse S100b, His	Recombinant Mouse S100 Calcium Binding Protein B, His Tag
PRO-1236	重组恒河猴S100钙结合蛋白B	Rhesus Macaque S100b	Recombinant Rhesus Macaque S100 Calcium Binding Protein B
pro-156	重组人S100钙结合蛋白G	Human S100G	Recombinant Human S100 Calcium Binding Protein G
pro-399	重组大鼠S100钙结合蛋白G	Rat S100G	Recombinant Rat S100 Calcium Binding Protein G
pro-425	重组人S100钙结合蛋白P	Human S100P	Recombinant Human S100 Calcium Binding Protein P
pro-830	重组人S100钙结合蛋白P	Human S100P His	Recombinant Human S100 Calcium Binding Protein P, His Tag
pro-840	重组人S100钙结合蛋白Z	Human S100Z	Recombinant Human S100 Calcium Binding Protein Z