AMH Muellerian缪勒管激素抑制因子抗体

¥780-2200
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进口/国产
2022-08-18 20:50

上海联迈生物工程有限公司

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产品属性
产品说明
AMH Muellerian缪勒管激素抑制因子抗体
英文名称AMH
中文名称Muellerian缪勒管激素抑制因子抗体
别 名MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance.
规格价格50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书50ul 100ul 200ul
研究领域肿瘤 细胞生物 发育生物学 信号转导 干细胞 生长因子和激素 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用WB=1:500-2000 ELISA=1:500-1000 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量57kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AMH:501-560/560
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008].

Function:
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. 

Subunit:
Homodimer; disulfide-linked. 

Subcellular Location:
Secreted. 

DISEASE:
Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry. 

Similarity:
Belongs to the TGF-beta family. 

SWISS:
P03971

Gene ID:
268

Database links:

Entrez Gene: 268 Human

Entrez Gene: 11705 Mouse

Entrez Gene: 25378 Rat

Omim: 600957 Human

SwissProt: P03971 Human

SwissProt: P27106 Mouse

SwissProt: P49000 Rat

Unigene: 112432 Human

Unigene: 19121 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品图片
Sample: 
293T(Human) Cell Lysate at 40 ug
Primary: Anti-AMH (bs-4687R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kD
Observed band size: 57 kD