关键词：NRCAM抗体;神经细胞粘附分子抗体;神经细胞粘附分子;Neuronal cell adhesion molecule; Neuronal surface protein Bravo; NgCAM-related cell adhesion molecule; Ng-CAM-related;ABP59534

中文名称：神经细胞粘附分子多克隆抗体/NRCAM Polyclonal Antibody

英文名称：NRCAM Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP59534.pdf

产品描述：兔抗-神经细胞粘附分子 多克隆抗体

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of NRCAM have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

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