MAVS (mitochondrial antiviral-signaling protein), also known as IPS1, KIAA1271, VISA or CARDIF, is a 540 amino acid protein that contains one CARD domain and several transmembrane domains, and localizes to the outer mitochondrial membrane. Expressed throughout the body with highest ex-pression in liver, heart, placenta, skeletal muscle and peripheral blood leuk-ocytes, MAVS functions downstream of proteins, such as RIG-I, that detect double-stranded (ds) viral replication and is required for proper immune re-sponse against ds viral infection. MAVS is thought to activate pathways that lead to the induction of antiviral cytokines and may protect the cells from viral-induced apoptosis. MAVS function can be inactivated via cleavage by a protease complex that degrades the CARD and transmembrane domains, thereby preventing MAVS from interacting with other proteins. Three isoforms of MAVS are expressed due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

MAVS (C-1) HRP: sc-365333 HRP. Direct western blot analysis of MAVS expression in Neuro-2A (A), TK-1 (B) and BYDP (C) whole cell lysates.

MAVS (C-1): sc-365333. Western blot analysis of MAVS expression in non-transfected: sc-117752 (A) and mouse MAVS transfected: sc-127129 (B) 293T whole cell lysates.

北京百奥创新科技有限公司：
一、辐射五大服务方向：
国内试剂耗材经销代理；国外试剂订购（直订或境外代理）；基因组测序（二代、二代+三代）；基因分型（SNP检测）：低/中/高通量项目；生物样本运输；
二、多家授权代理品牌，涉及30多种，经营代理500多个品牌：
Santa Cruz、G-Biosciences、Intact Genomic、Sigma、Epigentek、ThermoFisher、DNA Genotek、USA Scientific......
所有生物试剂耗材都可以进口，特别是冷门品牌，价格优，货期短，可加急。大部分客户我们提供货到付款服务，百奥创新自成立依靠过硬的服务和良好的信誉与各大企事业单位、科研单位建立长期合作。
专业订购国内外试剂耗材，常备现货，一手货源，欢迎合作
了解更多详情，请点击http://bestopbio.com/或拨打电话：4008883135